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Identifying functional populations among the interneurons in laminae I-III of the spinal dorsal horn [PDF]

open access: yesMolecular Pain, 2017
The spinal dorsal horn receives input from primary afferent axons, which terminate in a modality-specific fashion in different laminae. The incoming somatosensory information is processed through complex synaptic circuits involving excitatory and ...
A. Todd
semanticscholar   +3 more sources

Translatome of dorsal striatum parvalbumin interneurons revisited: insights across diverse experimental paradigms [PDF]

open access: yesFrontiers in Cellular Neuroscience
Parvalbumin (PV) interneurons in the dorsal striatum (DS) are fast-spiking GABAergic cells critical for feedforward inhibition and synaptic integration within basal ganglia circuits.
Claire Naon   +18 more
doaj   +2 more sources

Short-Term Amygdala Low-Frequency Stimulation Does not Influence Hippocampal Interneuron Changes Observed in the Pilocarpine Model of Epilepsy

open access: yesCells, 2021
Temporal lobe epilepsy (TLE) is characterized by changes in interneuron numbers in the hippocampus. Deep brain stimulation (DBS) is an emerging tool to treat TLE seizures, although its mechanisms are not fully deciphered. We aimed to depict the effect of
István Mihály   +6 more
doaj   +1 more source

Maternal Deprivation in Rats Decreases the Expression of Interneuron Markers in the Neocortex and Hippocampus

open access: yesFrontiers in Neuroanatomy, 2021
Early life stress has profound effects on the development of the central nervous system. We exposed 9-day-old rat pups to a 24 h maternal deprivation (MD) and sacrificed them as young adults (60-day-old), with the aim to study the effects of early stress
Milan Aksic   +10 more
doaj   +1 more source

Robust perisomatic GABAergic self-innervation inhibits basket cells in the human and mouse supragranular neocortex

open access: yeseLife, 2020
Inhibitory autapses are self-innervating synaptic connections in GABAergic interneurons in the brain. Autapses in neocortical layers have not been systematically investigated, and their function in different mammalian species and specific interneuron ...
Viktor Szegedi   +6 more
doaj   +1 more source

Cell-to-Cell Interactions Mediating Functional Recovery after Stroke

open access: yesCells, 2021
Ischemic damage in brain tissue triggers a cascade of molecular and structural plastic changes, thus influencing a wide range of cell-to-cell interactions.
Claudia Alia   +6 more
doaj   +1 more source

Roles and Transcriptional Responses of Inhibitory Neurons in Learning and Memory

open access: yesFrontiers in Molecular Neuroscience, 2021
Increasing evidence supports a model whereby memories are encoded by sparse ensembles of neurons called engrams, activated during memory encoding and reactivated upon recall.
Corinna Giorgi   +2 more
doaj   +1 more source

Alzheimer’s disease brain-derived extracellular vesicles spread tau pathology in interneurons

open access: yesBrain : a journal of neurology, 2020
Ruan et al. show that brain-derived extracellular vesicles from human donors with Alzheimer’s disease propagate tau more efficiently when injected into the mouse hippocampus than oligomeric or fibrillary tau from the same donors.
Zhi Ruan   +16 more
semanticscholar   +1 more source

Progression of Fetal Brain Lesions in Tuberous Sclerosis Complex

open access: yesFrontiers in Neuroscience, 2020
Tuberous sclerosis (TSC) is a multisystem autosomal dominant genetic disorder due to loss of function of TSC1/TSC2 resulting in increased mTOR (mammalian target of rapamycin) signaling.
Antoinette Bernabe Gelot   +2 more
doaj   +1 more source

Building thalamic neuronal networks during mouse development

open access: yesFrontiers in Neural Circuits, 2023
The thalamic nuclear complex contains excitatory projection neurons and inhibitory local neurons, the two cell types driving the main circuits in sensory nuclei.
Irene Huerga-Gómez   +2 more
doaj   +1 more source

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