Results 21 to 30 of about 145,959 (288)

Hippocampal GABAergic Inhibitory Interneurons [PDF]

open access: yesPhysiological Reviews, 2017
In the hippocampus GABAergic local circuit inhibitory interneurons represent only ~10–15% of the total neuronal population; however, their remarkable anatomical and physiological diversity allows them to regulate virtually all aspects of cellular and circuit function. Here we provide an overview of the current state of the field of interneuron research,
Pelkey, Kenneth A.   +5 more
openaire   +4 more sources

Modeling interneuron-specific (IS) interneurons in hippocampus [PDF]

open access: yesBMC Neuroscience, 2014
The hippocampus and cortex have a large diversity in inhibitory interneuron types. These local interneurons exert inhibitory control over neuronal populations in the hippocampus [1]. Although much is known about how hippocampal inhibitory interneurons exert control over pyramidal cells and synchronize local network activity, less is known about how the
Guet-McCreight, Alexandre   +3 more
openaire   +2 more sources

Interneuron development and dysfunction [PDF]

open access: yesThe FEBS Journal, 2021
Understanding excitation and inhibition balance in the brain begins with the tale of two basic types of neurons, glutamatergic projection neurons and GABAergic interneurons. The diversity of cortical interneurons is contributed by multiple origins in the ventral forebrain, various tangential migration routes, and complicated regulations of intrinsic ...
Jiaxin Yang, Xiong Yang, Ke Tang
openaire   +2 more sources

Identifying functional populations among the interneurons in laminae I-III of the spinal dorsal horn [PDF]

open access: yes, 2017
The spinal dorsal horn receives input from primary afferent axons, which terminate in a modality-specific fashion in different laminae. The incoming somatosensory information is processed through complex synaptic circuits involving excitatory and ...
Todd, Andrew J.
core   +1 more source

Central pattern generator for swimming in Melibe [PDF]

open access: yes, 2005
The nudibranch mollusc Melibe leonina swims by bending from side to side. We have identified a network of neurons that appears to constitute the central pattern generator (CPG) for this locomotor behavior, one of only a few such networks to be described ...
Thompson, Stuart, Watson, Winsor H., III
core   +3 more sources

Gene-Environment Interaction in a Conditional NMDAR-Knockout Model of Schizophrenia

open access: yesFrontiers in Behavioral Neuroscience, 2019
Interactions between genetic and environmental risk factors take center stage in the pathology of schizophrenia. We assessed if the stressor of reduced environmental enrichment applied in adulthood provokes deficits in the positive, negative or cognitive
Alexei M. Bygrave   +6 more
doaj   +1 more source

Notch Dosage: Jagged1 Haploinsufficiency Is Associated With Reduced Neuronal Division and Disruption of Periglomerular Interneurons in Mice

open access: yesFrontiers in Cell and Developmental Biology, 2020
Neural stem cells in the lateral ganglionic eminence (LGE) generate progenitors that migrate through the rostral migratory stream (RMS) to repopulate olfactory bulb (OB) interneurons, but the regulation of this process is poorly defined.
Christopher A. Blackwood   +6 more
doaj   +1 more source

Cell-type-specific synaptic modulation of mAChR on SST and PV interneurons

open access: yesFrontiers in Psychiatry, 2023
The muscarinic acetylcholine receptor (mAChR) antagonist, scopolamine, has been shown to have a rapid antidepressant effect. And it is believed that GABAergic interneurons play a crucial role in this action.
Huanxin Chen   +14 more
doaj   +1 more source

Membrane resonance enables stable and robust gamma oscillations [PDF]

open access: yes, 2012
Neuronal mechanisms underlying beta/gamma oscillations (20-80 Hz) are not completely understood. Here, we show that in vivo beta/gamma oscillations in the cat visual cortex sometimes exhibit remarkably stable frequency even when inputs fluctuate ...
Moca, Vasile V.   +3 more
core   +1 more source

Cortical interneurons in autism

open access: yesNature Neuroscience, 2021
The mechanistic underpinnings of autism remain a subject of debate and controversy. Why do individuals with autism share an overlapping set of atypical behaviors and symptoms, despite having different genetic and environmental risk factors? A major challenge in developing new therapies for autism has been the inability to identify convergent neural ...
Anis Contractor   +2 more
openaire   +4 more sources

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