Results 51 to 60 of about 176,830 (333)

Contrasting roles of axonal (pyramidal cell) and dendritic (interneuron) electrical coupling in the generation of neuronal network oscillations [PDF]

, 2003
Electrical coupling between pyramidal cell axons, and between interneuron dendrites, have both been described in the hippocampus. What are the functional roles of the two types of coupling?
Bibbig, A., Buhl, E.H., Hormuzdi, S.G., LeBeau, F.E.N., Monyer, H., Pais, I., Traub, R.D., Whittington, M.A.   +7 more
core   +2 more sources

Interneurons Scratch an Itch [PDF]

Neuron, 2014
Itch is immensely frustrating. Most studies focus on the cause of itch. In this issue of Neuron, Kardon et al. (2014) find that itch can be modulated by inhibitory neurons that produce dynorphin, an endogenous agonist of κ-opioid receptors.
Pereira, Paula Juliana Seadi, Lerner, Ethan A.   +1 more
openaire   +2 more sources

Selected issues of GABA metabolism and its potential role in neuropsychiatric disorders.

Journal of Medical Science, 2017
This mini review is limited to chosen problems about GABA metabolism mainly in aspect of associated disorders. GABA primarily identified as inhibitory neurotransmitter plays also excitatory function.
Andrzej Kostyrko
doaj   +1 more source

Dissociation of somatostatin and parvalbumin interneurons circuit dysfunctions underlying hippocampal theta and gamma oscillations impaired by amyloid β oligomers in vivo

Brain Structure and Function, 2020
Accumulation of amyloid β oligomers (AβO) in Alzheimer’s disease (AD) impairs hippocampal theta and gamma oscillations. These oscillations are important in memory functions and depend on distinct subtypes of hippocampal interneurons such as somatostatin ...
H. Chung, Kyerl Park, H. Jang, M. Kohl, J. Kwag   +4 more
semanticscholar   +1 more source

Dopamine-modulated dynamic cell assemblies generated by the GABAergic striatal microcircuit [PDF]

, 2009
The striatum, the principal input structure of the basal ganglia, is crucial to both motor control and learning. It receives convergent input from all over the neocortex, hippocampal formation, amygdala and thalamus, and is the primary recipient of ...
Alexander, Bar-Gad, Bauswein, Beiser, Belluardo, Berke, Berke, Bevan, Blackwell, Bolam, Bracci, Bracci, Brown, Burke, Buzsaki, Carrillo-Reid, Centonze, Cho, Czubayko, Dawson, Djurfeldt, Ferro, Frank, Fukai, Galan, Galarreta, Galvan, Gerfen, Glynn, Gonon, Gorelova, Groenewegen, Gurney, Humphries, Humphries, Humphries, Hurd, Ingham, Izhikevich, Izhikevich, Jaeger, Jahr, Kawaguchi, Kawaguchi, Kevin Gurney, Kirik, Kita, Koos, Koos, Kubota, Kwok, Lago-Fernandez, Mallet, Mark D. Humphries, Markram, McGeorge, Miller, Moyer, Newman, Newman, Nisenbaum, Nishikawa, Oorschot, O’Donnell, Pennartz, Plenz, Redgrave, Ric Wood, Richtand, Sandstrom, Schultz, Schwarting, Smith, Sullivan, Surmeier, Tang, Tateno, Taverna, Tepper, Traub, Tseng, Tunstall, Turner, Venton, Wang, Watts, Whishaw, Wickens, Wickens, Wilson, Yin, Zheng, Zhou   +92 more
core   +1 more source

Dysfunction of cortical GABAergic neurons leads to sensory hyper-reactivity in a Shank3 mouse model of ASD. [PDF]

, 2020
Hyper-reactivity to sensory input is a common and debilitating symptom in individuals with autism spectrum disorders (ASD), but the neural basis underlying sensory abnormality is not completely understood.
Chen, Naiyan, Chen, Qian, Deister, Christopher A, Dimidschstein, Jordane, Feng, Guoping, Feng, Shijing, Fishell, Gord, Gao, Xian, Goard, Michael J, Guo, Baolin, Liao, Weiping, Liu, Runpeng, Lu, Zhonghua, Lynn-Jones, Taylor, Moore, Christopher I, Shi, Yiwu, Wells, Michael F   +16 more
core   +1 more source

Sex differences in the distribution and density of regulatory interneurons in the striatum

Frontiers in Cellular Neuroscience
IntroductionDysfunction of the cortico-basal circuitry – including its primary input nucleus, the striatum – contributes to neuropsychiatric disorders, such as autism and Tourette Syndrome (TS).
Meghan Van Zandt, Deirdre Flanagan, Christopher Pittenger, Christopher Pittenger, Christopher Pittenger, Christopher Pittenger, Christopher Pittenger   +6 more
doaj   +1 more source

Genetically altered AMPA-type glutamate receptor kinetics in interneurons disrupt long-range synchrony of gamma oscillation [PDF]

, 2001
Gamma oscillations synchronized between distant neuronal populations may be critical for binding together brain regions devoted to common processing tasks.
A. Bibbig, A. Caputi, Ali, Angulo, Aroniadou, Asada, Bonnerot, Buhl, Catania, Catania, Csicsvari, E. C. Fuchs, Erlander, Ermentrout, Esclapez, Geiger, Geiger, Gu, Guly  s, H. Doheny, H. Faulkner, H. Monyer, He, Hestrin, Jonas, Karbowski, Kondo, Lambolez, Leranth, M. A. Whittington, Mahanty, Martina, Miles, Mosbacher, Mountford, Murakoshi, N. Kopell, Nagy, Petralia, R. D. Traub, Racca, Rozov, Singer, Sommer, Szab  , Traub, Traub, Traub, T  th, Vissavajjhala, Whittington, Whittington   +51 more
core   +3 more sources

Synaptic plasticity facilitates oscillations in a V1 cortical column model with multiple interneuron types

Frontiers in Computational Neuroscience
Neural rhythms are ubiquitous in cortical recordings, but it is unclear whether they emerge due to the basic structure of cortical microcircuits or depend on function.
Giulia Moreni, Licheng Zou, Cyriel M. A. Pennartz, Cyriel M. A. Pennartz, Jorge F. Mejias, Jorge F. Mejias   +5 more
doaj   +1 more source

GABAAR-mediated tonic inhibition differentially modulates intrinsic excitability of VIP- and SST- expressing interneurons in layers 2/3 of the somatosensory cortex

Frontiers in Cellular Neuroscience, 2023
Extrasynaptic GABAA receptors (GABAARs) mediating tonic inhibition are thought to play an important role in the regulation of neuronal excitability. However, little is known about a cell type-specific tonic inhibition in molecularly distinctive types of ...
Karolina Bogaj, Roksana Kaplon, Joanna Urban-Ciecko   +2 more
doaj   +1 more source