Results 111 to 120 of about 996,321 (170)

Investigation of IRE1/XBP1s pathway and its potential as a therapeutic target in breast cancer

, 2016
X-Box binding protein 1 (XBP1) is an integral component of the unfolded protein response (UPR), a pro-survival mechanism, triggered by the onset of endoplasmic reticulum stress.
Cleary, Patricia
core  

JNK and p53 cause human and mouse β cell death during excessive unfolded protein response. [PDF]

J Clin Invest
Sharma RB, Darko C, Wang Y, Castro TA, Lama TD, Gablaski B, Rappa A, Redmond D, Kim JK, Lee AS, Alonso LC.   +10 more
europepmc   +1 more source

Targeting the unfolded protein response in cancer: mechanisms, small-molecule inhibitors, and translational challenges. [PDF]

Front Immunol
Lin M, Li Z.
europepmc   +1 more source

Unfolded Protein Response in Glioblastoma: Mechanisms of Proteostasis, Tumor Adaptation, and Therapeutic Relevance. [PDF]

Neurochem Res
Caglar HO.
europepmc   +1 more source

Investigating Translocation Mechanisms of TDP-43 Into the Endoplasmic Reticulum Using Budding Yeast Models. [PDF]

Traffic
Saito M, Tsuzuki H, Hosomi A.
europepmc   +1 more source

Hac1-independent functions of Ire1 drive morphogenesis in Candida albicans through distinct transcriptional programs. [PDF]

J Cell Sci
Stack-Couture S, Nunes Marsiglio Librais G, Lung B, Genereaux J, Halder V, Dumeaux V, Shapiro RS, Lajoie P.   +7 more
europepmc   +1 more source

IRE1-XBP1driven induction of TMED9 stabilizes ATF6 during ER stress to promote cell survival. [PDF]

Cell Mol Biol Lett
Lenchisky C, Muhammad Majadly A, Bronshtein Berger I, Biton D, Daoud Sarsour A, Arbeli N, Cohen T, Amos N, Kinstlinger S, Cohen O, Horwitz E, Dvela-Levitt M.   +11 more
europepmc   +1 more source

Endoplasmic Reticulum Stress as a Stage-Dependent Regulatory Hub in Rheumatoid Arthritis. [PDF]

J Inflamm Res
Hu N, Song Y, Yu T, Li H, Wang X, Lv Q.
europepmc   +1 more source

<i>Lactobacillus johnsonii</i> N5 Supernatant Protects RPMI-2650 Cells from HDM-Induced Injury in Association with Suppression of the NR4A1-IRE1-XBP1-Mediated Unfolded Protein Response. [PDF]

Metabolites
Ma W, Chen Y, Feng Y, Yuan L, Liu H, Sun Y, Xu Z, Cai D, Sun H.   +8 more
europepmc   +1 more source

Endoplasmic reticulum stress in disease pathogenesis: its implications for therapy. [PDF]

Signal Transduct Target Ther
Wei S, Zhang N, Zhang H, Chen Z, Li S, Wu W, Liu Z, Xia Z, Luo P, Cheng Q.   +9 more
europepmc   +1 more source