Results 1 to 10 of about 5,271 (206)

Asymmetric Synthesis of Functionalized 2-Isoxazolines. [PDF]

ACS Omega
The asymmetric synthesis of the isoxazoline skeleton was achieved by the oxidation of hydroxylaminoalkyl furan prepared from simple starting materials: 2-methylfuran and (S)-epichlorohydrin. The synthesis features an NBS-mediated oxidation of hydroxylaminoalkyl furan to give an α,β-unsaturated ketone intermediate which cyclized to the isoxazoline.
Hamur B, Albayrak Halac F, Yilmazer F, Fleming FF, Kulu I, Altundas R.   +5 more
europepmc   +5 more sources

The mosquitocidal activity of isoxazoline derivatives afoxolaner, lotilaner, and fluralaner are not affected by mosquito sugar or antibiotic treatment [PDF]

Scientific Reports
Long-lasting insecticidal nets and indoor residual sprays have played a major role in significantly reducing the burden of malaria. However, the management of mosquitoes resistant to current insecticides continues to be challenging.
Harouna Soré, Wamdaogo Moussa Guelbeogo, Soumanaba Zongo, Judith M. Bolscher, Nicolas Ouédraogo, Adama Gansané, Teun Bousema, Katharine A. Collins, Koen J. Dechering   +8 more
doaj   +5 more sources

Ultrasound Assisted One-Pot Synthesis of Novel 3-(Aryl)-5-((4-(phenyldiazenyl)phenoxy)methyl)isoxazolines in Water [PDF]

Molbank, 2022
In this work, we present an efficient one-pot method for the synthesis of three new azo-isoxazoline derivatives (4a–c) from aromatic aldehydes, hydroxylamine hydrochloride and 4-(allyloxy)azobenzene.
Ayoub El Mahmoudi, Khalid Karrouchi, Hamza Tachallait, Khalid Bougrin   +3 more
doaj   +2 more sources

Studies of the Synthesis of Fused Isoxazoline/Isoquinolinones and Evaluation of the Antifungal Activity of Isoxazole-like Benzamide and Isoquinolinone Hybrids [PDF]

Molecules
Isoxazole derivatives (isoxazoles, isoxazolines, and isoxazolidines) are present in the structure of several natural products and/or pharmaceutically interesting compounds.
Konstantinos A. Ouzounthanasis, Jasmina Glamočlija, Ana Ćirić, Alexandros E. Koumbis   +3 more
doaj   +2 more sources

A novel method for the determination of isoxazoline derivatives in plasma by ultra-high performance liquid chromatography–tandem mass spectrometry: validation and applicability to screening tests [PDF]

Journal of Veterinary Research
Isoxazoline derivatives such as fluralaner, sarolaner, lotilaner, and afoxolaner are a new class of insecticide and acaricide compounds. These compounds are characterised by rapid action and high efficacy over a period of up to several weeks.
Markowska-Buńka Paulina, Jaroszewski Jerzy J., Rasiński Bartosz, Ziółkowski Hubert   +3 more
doaj   +2 more sources

[Simultaneous identification and detection of four novel isoxazoline drugs in bovine-origin foods using ultra-high performance liquid chromatography coupled to quadrupole/linear ion trap mass spectrometry]. [PDF]

Se Pu
Yang C, Zhu WX, Liu YF, Wei W, Zhao F, Hu K, Zhao WJ.   +6 more
europepmc   +3 more sources

Synthesis of Functionalized 4,5-Dihydroisoxazoles Decorated with the Dimethylphosphinoyl Group

Журнал органічної та фармацевтичної хімії, 2023
Aim. To synthesize a hybrid molecular platform incorporating dimethylphosphinoyl and 4,5-dihydroisoxazole moieties suitable for the creation of focused combinatorial libraries of compounds. Results and discussion.
Andrii V. Fedyk, Bohdan A. Chalyk
doaj   +1 more source

Toxicity and Sublethal Effects of Fluxametamide on the Key Biological Parameters and Life History Traits of Diamondback Moth Plutella xylostella (L.)

Agronomy, 2022
Fluxametamide, a novel isoxazoline insecticide, is newly registered for the control of various lepidopteran, coleopteran and thysanopteran insect pests on lethal and sublethal levels.
Amit Gope, Gautam Chakraborty, Shanowly Mondal Ghosh, Sayan Sau, Krishnendu Mondal, Abhisek Biswas, Sukamal Sarkar, Pijush Kanti Sarkar, Debashis Roy   +8 more
doaj   +1 more source

Synthesis, DFT Study and Antibacterial Activity of some Isoxazoline Derivatives Containing 1,4-benzothiazin-3-one Nucleus Obtained Using 1,3-dipolar Cycloaddition Reaction [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2020
Novel series of isoxazoline derivatives containing 1,4-benzothiazin-3-one ring (6a-h) were synthesized via 1,3-dipolar cycloaddition reactions of arylnitrile oxides 5a-d on 4-allyl-2-(substituted)-1,4-benzothiazin-3-ones 3 and 4 led to polyheterocyclic ...
Sebbar Nada Kheira, Taha Mohamed Labd, Ellouz Mohamed, Essassi El Mokhtar, Zerzouf Abdelfettah, Karrouchi Khalid, Ouzidan Younes, Mennane Zakaria, T. Mague Joel   +8 more
doaj   +1 more source

Liver and spleen of hosts of Rhipicephalus linnaei exposed to synthetic (afoxolaner) and natural acaricides (esters from castor oil). A comparative clinical-morphological study [PDF]

Revista Brasileira de Parasitologia Veterinária, 2023
In dogs, Rhipicephalus linnaei transmits pathogens such as Ehrlichia canis, Babesia vogeli, and Hepatozoon canis. The veterinary market has synthetic acaricides to ticks control. Esters derived from castor oil are efficient.
Luís Fernando Sodelli, Odaiza da Silva, Bruna Jéssyca Nascimento Araújo, Maria Izabel Camargo-Mathias   +3 more
doaj   +1 more source