Results 71 to 80 of about 22,259 (219)

Inhibition of carbachol-induced inositol phosphate accumulation in the embryonic retina promoted by kainate and veratridine

Brazilian Journal of Medical and Biological Research, 1998
In the present study, we report that low concentrations of the glutamate ionotropic agonist kainate decreased the turnover of [3H]-phosphoinositides ([3H]-InsPs) induced by muscarinic receptors in the chick embryonic retina.
G. Sanches, A.L.M. Ventura
doaj   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source

Energy metabolism, adenosine, and glutamate signaling reprogramming by decanoic acid in Glut1 disorder syndrome

Epilepsia Open, Volume 11, Issue 3, Page 1036-1045, June 2026.
Abstract Glut1 deficiency syndrome (Glut1DS) leads to neurological and cognitive symptoms and is primarily treated using carbohydrate‐restricted ketogenic diets. However, a recent clinical trial of a less restrictive, non‐ketogenic, medium chain triglyceride (MCT) diet with a high decanoic acid content suggests efficacy in Glut1DS treatment.
Erwann Pain, Yatra Kapatel, Pankaj K. Singh, Katie Lloyd Jones, Jamuna Selvakumaran, Alberto Malerba, Walter Lucchesi, Tricia Rutherford, Christina A. Gurnett, Matthew C. Walker, Robin S. B. Williams   +10 more
wiley   +1 more source

Kainate Promotes Alterations in Neuronal RNA Splicing Machinery

, 2016
Kainate, a glutamate analogue, activates kainate and AMPA receptors inducing strong synaptic activation. Systemic kainate application to rodents results in seizures, neurodegeneration, and neuronal remodeling in the brain.
Claus Zabel (51014), Joachim Klose (51015), Michael Rohe (51011), Grit Nebrich (264456), Daniela Hartl (51010), Oliver Klein (108602), Lei Mao (51012)   +6 more
core   +1 more source

LTD expression is independent of glutamate receptor subtype

Frontiers in Synaptic Neuroscience, 2014
Long-term depression (LTD) is a form of synaptic plasticity that plays a major role in the activity-dependent reshaping of synaptic transmission.
Adam J Granger, Roger A Nicoll
doaj   +1 more source

Venom and toxins from Argiope lobata: electrophysiological studies

Біологічні студії, 2020
The purpose of this study was to present experimental data on the action of venom and toxins from Argiope lobata spiders on the glutamate channel-receptor complex.
O. M. Klyuchko
doaj   +1 more source

Brain–Computer Interfaces: The Dawn of a New Era in Disease Treatment

Exploration, Volume 6, Issue 3, June 2026.
This study investigates the potential of brain–computer interface (BCI) technology in treating neuropsychiatric disorders, such as movement and communication barriers. Our review examines the history, signal paradigms, and diverse applications of BCI while also discussing ongoing research into novel materials and emerging technologies that offer ...
Yuqi Feng, Wangzheqi Zhang, Jun Chen, Huang Wu, Lei Wu, Yanhao Qiu, Xiaoming Deng, Chenglong Zhu, Yisheng Chen, Zhijie Zhao, Changli Wang, Xiaomin Zhang   +11 more
wiley   +1 more source

A Transmembrane Accessory Subunit that Modulates Kainate-Type Glutamate Receptors

, 2009
SummaryGlutamate receptors play major roles in excitatory transmission in the vertebrate brain. Among ionotropic glutamate receptors (AMPA, kainate, NMDA), AMPA receptors mediate fast synaptic transmission and require TARP auxiliary subunits.
Burlingame, Alma L., Howe, James R., Sumioka, Akio, Tomita, Susumu, Jonathan C. Trinidad, Zhang, Wei, Trinidad, Jonathan C., Morimoto-Tomita, Megumi, Wei Zhang, Susumu Tomita, Kwang S. Kim, James R. Howe, Megumi Morimoto-Tomita, Chad P. Grabner, Straub, Christoph, St-Gelais, Fannie, Grabner, Chad P., Akio Sumioka, Christoph Straub, Alma L. Burlingame, Kim, Kwang S., Fannie St-Gelais   +21 more
core   +1 more source

Increased expression of aromatase after focal cerebral ischemia: Relevance to neuroprotection and functional recovery

Neuroprotection, Volume 4, Issue 2, Page 143-156, June 2026.
Abstract Aim Aromatase is the key enzyme in the biosynthesis of 17β‐estradiol, the most potent estrogen, which has pleiotropic neuroprotective properties. Aromatase levels increase in the brain after stroke, and its gene variants increase susceptibility to stroke. This study aims to determine whether aromatase overexpression improves stroke outcome and
Lindsay Gallagher, Anna F. Dominiczak, Luis M. Garcia‐Segura, Nobuhiro Harada, J. B. Hutchison, James M. Mullin, Delyth Graham, Peter O'Shaughnessy, Hilary Victoria O. Carswell   +8 more
wiley   +1 more source

Involvement of kainate glutamate receptors in the modulation of neuronal transmission in brain areas involved in migraine pathophysiology

, 2009
Migraine pathophysiology is thought to involve activation of the trigeminal fibres which innervate dural structures. The nociceptive inflow from the meninges is relayed to the trigeminocervical complex (TCC), before ascending to higher brain areas ...
Andreou, A.
core