Lipid Anti-Lipid Antibody Responses Correlate with Disease Activity in Systemic Lupus Erythematosus [PDF]
10.1371/journal.pone.0055639PLoS ...
Abdul Aziz, N. +15 more
core +3 more sources
Endogenous cholesterol synthesis is associated with VLDL-2 apoB-100 production in healthy humans
Subjects with high plasma cholesterol levels exhibit a high production of VLDL apolipoprotein B-100 (apoB-100), suggesting that cholesterol is a mediator for VLDL production.
Berthil H.C.M.T. Prinsen +8 more
doaj +1 more source
Background: Several factors could lead to lipid disturbances observed in cystic fibrosis (CF). This study aimed to assess sterol homeostasis in CF and define potential exogenous and endogenous determinants of lipid dysregulation.
Sławomira Drzymała-Czyż +9 more
doaj +1 more source
The association between low birth weight and high levels of cholesterol is not due to increased cholesterol synthesis or absorption: analysis in twins [PDF]
Low birth weight may be associated with high levels of cholesterol in later life through genetic factors that affect both birth weight and cholesterol metabolism.
Boomsma, D.I. +5 more
core +4 more sources
Biosynthesis of squalene and sterols by rat aorta
The synthesis of nonsaponifiable compounds from radioactive mevalonate by segments of adult rat aorta was studied in vitro. The labeled products consisted largely of substances with the chromatographic and chemical behavior of squalene, lanosterol ...
MARIE M. DALY
doaj +1 more source
Phylogenomic analysis of integral diiron membrane histidine motif-containing enzymes in ciliates provides insights into their function and evolutionary relationships [PDF]
The Integral Membrane Histidine Motif-containing Enzymes (IMHME) are a class of binuclear non-heme iron proteins widely distributed among prokaryotes and eukaryotes.
Cid, Nicolás Gonzalo +5 more
core +1 more source
Cholesterol metabolism in primary biliary cirrhosis during simvastatin and UDCA administration
Little is known about the effects of cholesterol-lowering agents in hypercholesterolemic patients with primary biliary cirrhosis (PBC). The aim of this study was to compare the changes induced by simvastatin and ursodeoxycholic acid (UDCA) on cholesterol
M. Del Puppo +6 more
doaj +1 more source
Lathosterolosis: an inborn error of human and murine cholesterol synthesis due to lathosterol 5-desaturase deficiency [PDF]
Lathosterol 5-desaturase catalyzes the conversion of lathosterol to 7-dehydrocholesterol in the next to last step of cholesterol synthesis. Inborn errors of cholesterol synthesis underlie a group of human malformation syndromes including Smith-Lemli-Opitz syndrome, desmosterolosis, CHILD syndrome, CDPX2 and lathosterolosis. We disrupted the lathosterol
Patrycja A, Krakowiak +11 more
openaire +5 more sources
Reduced cholesterol synthesis has been reported in patients with primary biliary cirrhosis but no data are available on changes in cholesterol catabolism induced by the disease.
M. Del Puppo +4 more
doaj +1 more source
Protection of the Ovine Fetal Gut against Ureaplasma-Induced Chorioamnionitis: A Potential Role for Plant Sterols [PDF]
Chorioamnionitis, clinically most frequently associated with Ureaplasma, is linked to intestinal inflammation and subsequent gut injury. No treatment is available to prevent chorioamnionitis-driven adverse intestinal outcomes. Evidence is increasing that
Alan H. Jobe +18 more
core +4 more sources

