Results 81 to 90 of about 2,855 (207)
Systematic Review with Meta‐Analysis of Biofluid Markers for Huntington's Disease
Movement Disorders, Volume 40, Issue 12, Page 2578-2595, December 2025.Eight Huntington's Disease Biofluid Markers show Meta‐Analytic Significance Across HD‐ISS Stages. Meta‐analyses were conducted for two types of biomarkers: Different from demographically‐matched healthy controls and *Showing change over time. Abstract Primary therapeutic objectives for Huntington's disease (HD) necessitate continued therapy for a long ...
Jane S. Paulsen +9 more
wiley +1 more source
Journal of Lipid Research, 2010 Moderately elevated levels of plasma plant sterols have been suspected to be causally involved in atherosclerosis. The aim of this study was to investigate whether plant sterols and other markers of sterol metabolism predicted all-cause and ...
Guenther Silbernagel +6 more
doaj +1 more source
Impact of milk consumption on cardiometabolic risk in postmenopausal women with abdominal obesity [PDF]
, 2015 Background The impact of dairy intake on cardiometabolic risk factors associated with metabolic syndrome (MetS) needs further research. Objective To investigate the impact of ...
Amélie Charest +9 more
core +1 more source
European Journal of Neurology, Volume 32, Issue 11, November 2025.Three AD patients sharing the same heterozygous NPC1 mutation were orally treated with miglustat for 12 months and underwent monthly clinical and neuropsychological evaluations, brain amyloid‐PET imaging, and biochemical analyses on plasma and CSF. All three patients achieved clinical stability, showed a sustained reduction in serum oxysterol levels ...
Diego Lopergolo +10 more
wiley +1 more source
Defining the Place of Ezetimibe/Atorvastatin in the Management of Hyperlipidemia [PDF]
, 2016 Statin-ezetimibe combinations are a potentially advantageous therapeutic option for high-risk patients who need additional lowering of low-density lipoprotein cholesterol (LDL-C).
Ferreira, AM, Marques da Silva, P
core +1 more source
Advanced Science, Volume 12, Issue 38, October 13, 2025.The study found that RPL6 is frequently upregulated in HCC tissues with extrahepatic metastasis. Elevated RPL6 bound to and increased the stability of HMGCS1 mRNA, thereby enhancing intracellular cholesterol levels. Subsequently, increased cholesterol promotes cancer metastasis in HCC by stabilizing HIF‐1α protein.
Minli Yang +15 more
wiley +1 more source
Brain cholesterol in normal and pathological aging [PDF]
, 2011 Aberrations in cerebral cholesterol homeostasis can lead to severe neurological diseases. Recent findings strengthen the link between brain cholesterol metabolism and factors involved in synaptic plasticity, a process essential for learning and memory ...
Lütjohann, D. (Dieter) +2 more
core +5 more sources
Neurobiology of Disease, 2017 Cholesterol precursors and cholesterol levels are reduced in brain regions of Huntington's disease (HD) mice. Here we quantified the rate of in vivo de novo cholesterol biosynthesis in the HD brain.
Mahalakshmi Shankaran +11 more
doaj +1 more source
Randomized controlled trial of the effect of phytosterols-enriched low-fat milk on lipid profile in Chinese [PDF]
, 2017 published_or_final_versio
CHENG, KF +7 more
core +1 more source
Journal of Veterinary Internal Medicine, Volume 39, Issue 5, September/October 2025.ABSTRACT Background In previous studies, only a subset of dogs with chronic enteropathy (CE) had an increased dysbiosis index (DI) or altered fecal metabolites or both, suggesting differences in underlying intestinal pathophysiology between these subsets.
Chih‐Chun Chen +13 more
wiley +1 more source