Results 141 to 150 of about 8,120 (205)
Histone methyltransferase SUV39H1 regulates the Golgi complex via the nuclear envelope-spanning LINC complex. [PDF]
PLoS One, 2023 Nishino M +6 more
europepmc +1 more source
Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology
Advanced Science, Volume 13, Issue 33, 15 June 2026.Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu +4 more
wiley +1 more source
The LINC-less granulocyte nucleus
, 2009 The major blood granulocyte (neutrophil) is rapidly recruited to sites of bacterial and fungal infections. It is a highly malleable cell, allowing it to squeeze out of blood vessels and migrate through tight tissue spaces.
Olins, A.L. +8 more
core
Advanced Science, Volume 13, Issue 33, 15 June 2026.This study elucidates the mechanisms of subcellular multidimensional collapse in exhausted T cells. By specifically targeting the nucleus, mitochondria, and endoplasmic reticulum, strategic interventions can effectively remodel the compromised organelle network. This integrated approach drives comprehensive T cell resuscitation, ultimately establishing
Mingxing Wang +9 more
wiley +1 more source
Characterising SUN1 Mitotic Phosphorylation and its Effects on LINC Complex Interactions
, 2013 Mammalian inner nuclear membrane (INM) proteins, SUN1 and SUN2, interact with nesprins located on the outer nuclear membrane to form the linker of nucleoskeleton to cytoskeleton (LINC) complex.
Jennifer Tulsi Patel (7668773)
core +1 more source
The meiotic LINC complex component KASH5 is an activating adaptor for cytoplasmic dynein. [PDF]
J Cell Biol, 2023 Garner KEL +10 more
europepmc +1 more source
iNew Medicine, Volume 2, Issue 2, June 2026.ABSTRACT High‐grade serous ovarian cancer (HGSOC) is the most common and lethal histological subtype of ovarian cancer. This study aimed to identify peritoneal metastasis‐associated biomarkers of HGSOC to provide directions for subsequent treatment. Transcriptome data were extracted from the GEO database and literature. Differential expression analysis,
Jing Zhu +8 more
wiley +1 more source
TMX4-driven LINC complex disassembly and asymmetric autophagy of the nuclear envelope upon acute ER stress. [PDF]
Nat Commun, 2023 Kucińska MK +7 more
europepmc +1 more source
MicrobiologyOpen, Volume 15, Issue 3, June 2026.Alyteserin‐1c hexamer was investigated in biomimetic Gram‐positive and Gram‐negative membrane models using all‐atom molecular dynamics simulations to understand its membrane disruption behavior. The hexamer remained structurally stable in both membrane environments, with hydrophobic inter‐monomer interactions maintaining oligomer integrity while ...
Akshay Sasidharan +1 more
wiley +1 more source
Protein Science, Volume 35, Issue 6, June 2026.Abstract The tumor suppressor protein p53 plays a crucial role in cell cycle regulation. In approximately 50% of all tumors, mutations in p53 are observed. Although the top hot spot mutations impair DNA binding, other mutations affect the thermal stability of the protein, leading to its rapid denaturation in physiological conditions.
Jason Stahlecker +9 more
wiley +1 more source