Results 161 to 170 of about 7,490 (198)

Heat Stress Triggers Nuclear Invagination and Spatial Compartmentalization of Protein Metabolism

Cell Proliferation, Volume 59, Issue 8, August 2026.
Cells adapt heat stress to shape a nuclear invagination region function as “protein metabolism hotspots”, where both protein production and degradation are enhanced. ABSTRACT Heat stress is a common challenge for cells, causing multiple types of cellular damage while triggering complex stress responses, including the highly conserved mechanism known as
Zhi‐Hao Zhang, Yuan‐Tao Qiu, Jing‐Yue Cao, Yi‐Feng Huang, Ye‐Lin Lan, Yu‐Li Zhao, Fu Wu, Chen‐Long Wang, Guo‐Run Tang, Jing‐Yun Ji, Zhang Zhang, Guan‐Zheng Luo   +11 more
wiley   +1 more source

Crystal structure of SUN1-KASH6 reveals an asymmetric LINC complex architecture compatible with nuclear membrane insertion

, 2023
Gurusaran M, Erlandsen BS, Davies OR.
europepmc   +1 more source

Ensconsin-dependent changes in microtubule organization and LINC complex-dependent changes in nucleus-nucleus interactions result in quantitatively distinct myonuclear positioning defects. [PDF]

Mol Biol Cell, 2021
Collins MA, Coon LA, Thomas R, Mandigo TR, Wynn E, Folker ES.   +5 more
europepmc   +1 more source

The meiotic LINC complex component KASH5 is an activating adaptor for cytoplasmic dynein

, 2022
Garner KEL, Salter A, Lau CK, Gurusaran M, Villemant C, Granger EP, McNee G, Woodman PG, Davies OR, Burke BE, Allan VJ.   +10 more
europepmc   +1 more source

RAC1 induces nuclear alterations through the LINC complex to enhance melanoma invasiveness. [PDF]

Mol Biol Cell, 2020
Colón-Bolea P, García-Gómez R, Shackleton S, Crespo P, Bustelo XR, Casar B.   +5 more
europepmc   +1 more source

The crystal structure of SUN1-KASH6 reveals an asymmetric LINC complex architecture compatible with nuclear membrane insertion. [PDF]

Commun Biol
Gurusaran M, Erlandsen BS, Davies OR.
europepmc   +1 more source

LINC complex protein nesprin-2 has pro-apoptotic activity via Bcl-2 family proteins. [PDF]

Cell Death Discov
Lindenboim L, Zohar H, Gundersen GG, Worman HJ, Stein R.   +4 more
europepmc   +1 more source

Apoptotic stress induces Bax-dependent, caspase-independent redistribution of LINC complex nesprins. [PDF]

Cell Death Discov, 2020
Lindenboim L, Grozki D, Amsalem-Zafran AR, Peña-Blanco A, Gundersen GG, Borner C, Hodzic D, Garcia-Sáez AJ, Worman HJ, Stein R.   +9 more
europepmc   +1 more source

Recruitment of BAF to the nuclear envelope couples the LINC complex to endoreplication.

Development, 2020
Unnikannan CP, Reuveny A, Grunberg D, Volk T.   +3 more
europepmc   +1 more source

In-cell structure of a LINC complex reveals the molecular basis for membrane remodelling and head-to-tail coupling in sperm cells

Dendooven T, Ebrahimi M, dos Santos A, Dhondt W, Knowles O, Hale T, Burt A, Mehdipour AR, Allegretti M.   +8 more
europepmc   +1 more source