Results 151 to 160 of about 7,490 (198)

Disrupting the LINC complex by AAV mediated gene transduction prevents progression of Lamin induced cardiomyopathy. [PDF]

Nat Commun, 2021
Chai RJ, Werner H, Li PY, Lee YL, Nyein KT, Solovei I, Luu TDA, Sharma B, Navasankari R, Maric M, Sim LYE, Loh YJ, Aliwarga E, Cheong JWL, Chojnowski A, Autio MI, Haiyang Y, Boon Tan KK, Keng CT, Ng SL, Chew WL, Ferenczi M, Burke B, Foo RSY, Stewart CL.   +24 more
europepmc   +1 more source

Virtual Screening of Bacteriocins From Lactic Acid Bacteria Against Monkeypox DNA Polymerase: Sakacin P and Mundticin KS Emerge as Promising Candidates

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
This study employs an in silico virtual screening workflow to evaluate lactic acid bacteria (LAB)‐derived bacteriocins as potential inhibitors of the monkeypox virus DNA polymerase (MPDP). Protein‐peptide docking simulations using the HADDOCK platform revealed that Sakacin P and Mundticin KS possess the highest binding affinities for the MPDP target ...
Melisa Z. Karaman, Karan Goel, Fernando Berton Zanchi, Aykut Ozdarendeli, Somdutt Mujwar, Ahmet E. Yetiman, Ozkan Fidan   +6 more
wiley   +1 more source

The LINC Complex Regulates Tendon Elastic Modulus, Collagen Crimp, and Lateral Expansion During Early Postnatal Development. [PDF]

J Orthop Res
Pancheri NM, Daw JT, Ditton D, Schiele NR, Birks S, Uzer G, Jones CL, Penney BT, Theodossiou SK.   +8 more
europepmc   +1 more source

Lymphatic Endothelial Cells in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Lymphatic endothelial cells (LECs) are dynamic regulators of tissue homeostasis and disease remodeling. In the healthy state, LECs coordinate interstitial fluid drainage, intestinal lipid transport, and immune trafficking and tolerance. Across disease settings, however, these same programs become maladaptively reprogrammed, contributing to barrier ...
Du Tang, Wang Lin, Hengyang Liu, Jixin Zhong, Shiliang Li, Xiaoquan Rao   +5 more
wiley   +1 more source

Competitive Interfacial Partitioning in Cetyltrimethylammonium Bromide Self‐Assembly: A Coarse‐Grained Study Across Deep Eutectic Solvents

ChemistryOpen, Volume 15, Issue 8, August 2026.
Martini coarse‐grained simulations probe solvent–surfactant interactions of cetyltrimethylammonium bromide in choline chloride‐based deep eutectic solvents containing glycerol or urea. Competitive partitioning of the hydrogen‐bond donors around the surfactant headgroups accompanies striking composition‐dependent changes in micellar self‐assembly ...
Petteri A. Vainikka, Karen J. Edler
wiley   +1 more source

Thiol–Michael Addition to a Quinolin‐2‐One–Isoxazole Dye in Cationic CTABr Micellar Media: Insights From Experiments and Theory

ChemistryOpen, Volume 15, Issue 8, August 2026.
We report the reactivity of DQI toward bisulfite in CTABr micelles. CTABr enhances DQI fluorescence and promotes the reaction by increasing the solubility and local concentration. Spectroscopy, NMR, and DFT support the formation of a DQI•SO3H Michael adduct and identify preferred reactive sites. Herein we report an experimental and theoretical study of
Guillermo E. Quintero, Kevin Droguett, Costantino Zazza, Margarita E. Aliaga   +3 more
wiley   +1 more source

Testican‐1‐MMP axis in tumour extracellular matrix (ECM) remodelling: interaction dynamics analysis and an in silico perspective

The Journal of Pathology, Volume 269, Issue 4-5, Page 433-445, August 2026.
Abstract The extracellular matrix (ECM) plays a pivotal role in facilitating tumour development, invasiveness, metastasis, and immunoevasive processes through dynamic ECM remodelling processes. Testican‐1 (SPOCK1), an excretory matricellular proteoglycan, is suggested to exert a role in the facilitation of ECM remodelling processes through interacting ...
Sepideh Youssefi, Kiarash Saleki, Prerna Kadam, Amirreza Mazloomi, Abhik Mukherjee, Lodewijk V Dekker, Abdolrahman S Nateri   +6 more
wiley   +1 more source

Molecular and energetic basis of histidine switch dynamics in respiratory complex I

Protein Science, Volume 35, Issue 8, August 2026.
Abstract The respiratory complex I in mitochondria and bacteria drives the two‐electron reduction of quinone to pump protons across the membrane. The molecular basis of this catalytic reaction remains enigmatic despite significant progress in structural characterization of the complex.
Erik Endres, Mahdi Torabi, Mai Jousmäki, Kim Vy Huynh, Cristina Pecorilla, Oleksii Zdorevskyi, Volker Zickermann, Vivek Sharma   +7 more
wiley   +1 more source

First‐Time Demonstration of a Two‐Step Mechanism for Azo Dye Removal by Bacillus proteolyticus Using Molecular Docking and FT‐IR

Water Environment Research, Volume 98, Issue 8, August 2026.
Bacillus proteolyticus OA7, isolated from textile wastewater, efficiently removed Acid Red 88 (69.74%) and Acid Blue 193 (41.01%) through substrate‐dependent mechanisms. Acid Red 88 removal involved both biosorption and biodegradation, whereas Acid Blue 193 was mainly biosorbed. FT‐IR revealed functional group changes associated with EPS, proteins, and
Safiye Elif Korcan, Nevin Çankaya, Serap Yalçın Azarkan, Kübra Çitekçi, Şah İsmail Çivi, Gülderen Uysal Akkuş   +5 more
wiley   +1 more source

Osterix-driven LINC complex disruption in vivo diminishes osteogenesis at 8 weeks but not at 15 weeks. [PDF]

J Orthop Res
Birks S, Howard S, O'Rourke C, Thompson WR, Lau A, Uzer G.   +5 more
europepmc   +1 more source