Results 91 to 100 of about 8,119 (209)

Bridging maternal effects and epitranscriptomics: A novel perspective in developmental biology

Developmental Dynamics, Volume 255, Issue 7, Page 628-645, July 2026.
Abstract Maternal effects, encompassing both genetic (maternally expressed gene products) and non‐genetic (maternal state) influences, are powerful determinants of offspring phenotype, yet their RNA‐level mechanisms remain incompletely resolved. In parallel, epitranscriptomics, an emerging field centered on chemical modifications to RNA, has revealed ...
Ehsan Pashay Ahi
wiley   +1 more source

Projecting future damage costs of non‐native species using combined dynamical and cost–density equations

Ecological Applications, Volume 36, Issue 5, July 2026.
Abstract Biological invasions threaten biodiversity, economic stability, and public health, exacerbated by intensive global trade and transport. The economic costs of these invasions have exceeded US$2 trillion globally and continue to increase. Although past invasion costs have been described across various contexts, there are few robust projections ...
Danish A. Ahmed, Corey J. A. Bradshaw, Noor Tahat, Emma J. Hudgins, Pierre Courtois, Philip E. Hulme, Yuya Watari, Ali Serhan Tarkan, Ismael Soto, Phillip J. Haubrock, Paride Balzani, Ross N. Cuthbert   +11 more
wiley   +1 more source

Impacts of glacier retreat, greening, and a changing sediment supply on debris flows in contrasting monsoon‐dominated Himalayan climates

Earth Surface Processes and Landforms, Volume 51, Issue 7, July 2026.
We modified the SedCas model to assess how glacier retreat, vegetation growth, and sediment availability and erosion timing affect debris flow activity in Langtang and Mustang, Nepal. Results reveal that landscape change reduces sediment supply and runoff response, making debris flows smaller and less seasonally concentrated under future conditions ...
Varvara O. Bazilova, Jacob Hirschberg, Leon Duurkoop, Tjalling de Haas, Walter Immerzeel   +4 more
wiley   +1 more source

Table_2_Comprehensive Analysis of m5C Methylation Regulatory Genes and Tumor Microenvironment in Prostate Cancer.docx

, 2022
Background5-Methylcytidine (m5C) methylation is an emerging epigenetic modification in recent years, which is associated with the development and progression of various cancers.
Xin Gu (244758), Ming Zhan (27937), Jiahao Bao (12855575), Qing Yang (67856), Zhong Wang (132073), Yushan Liu (704070), Jiangyi Wang (6626843), Guopeng Yu (730431), Xinjuan Li (3599063), Bin Xu (10691), Shangqing Song (553292)   +10 more
core   +1 more source

Identification and verification of an ALYREF-involved 5-methylcytosine based signature for stratification of prostate cancer patients and prediction of clinical outcome and response to therapies

Discover Oncology, 2023
Objectives Due to the heterogeneity of PCa, the clinical indicators used for PCa can't satisfy risk prognostication and personalized treatment.
Xiao Tan, Zhouda Cai, Guo Chen, Chao Cai, Jiahong Chen, Yingke Liang, Yangjia Zhuo, Jianming Liu, Liangliang Huang, Bin Ouyang, Yanni Wei, Zhenyu Jia, Junhong Deng, Weide Zhong, Jianming Lu   +14 more
doaj   +1 more source

Salt Stress Adaptations in Soybean Involve Alterations in Pre‐mRNA Processing

Plant, Cell &Environment, Volume 49, Issue 7, Page 4000-4014, July 2026.
ABSTRACT Salt stress can seriously affect plant survival. To adapt to salt stress, plants can alter gene expressions and/or pre‐mRNA processing patterns, or both. Previous studies could not comprehensively profile stress‐responsive pre‐mRNA processing patterns due to limitations in traditional sequencing technologies.
Shoudong Zhang, Zhixia Xiao, Ailin Liu, Dongpeng Ren, Shengjie Chen, Hanxue Zhang, Li Zhang, Zhili Wang, Jun Yang, Hon‐Ming Lam   +9 more
wiley   +1 more source

RNA m5C methylation in cancer: mechanisms and biological impact

Oncogenesis
RNA modification, a prominent epigenetic mechanism, has been implicated in regulating RNA function, stability, processing, and interactions, including pseudouridylation, acetylation, and methylation. Recent evidence highlights that 5-methylcytosine (m5C) influences key cellular processes such as proliferation, differentiation, apoptosis, and stress ...
Zhenyu Guan, Wendong Li, Yuting He, Wenzhi Guo   +3 more
openaire   +2 more sources

Protocol for single-base quantification of RNA m5C by pyrosequencing

STAR Protocols
5-methylcytosine (m5C) is a common RNA modification found in both coding and non-coding RNAs. Here, we present a protocol for RNA-m5C-pyroseq for quantitative, single-nucleotide resolution analysis of RNA methylation. We describe steps for designing primers for the target region of RNA, performing bisulfite conversion of RNA, and using pyrosequencing ...
Cayir, Akin, Böttcher, Yvonne
openaire   +2 more sources

Image_5_Roles of m5C RNA Modification Patterns in Biochemical Recurrence and Tumor Microenvironment Characterization of Prostate Adenocarcinoma.tif

, 2022
BackgroundProstate cancer is the second most common cancer with a high risk of biochemical recurrence (BCR) among men. Recently, 5-methylcytosine (m5C) modification has attracted more attention as a new layer of RNA post-transcriptional regulation. Hence,
Ruiji Liu (11975807), Zhipeng Xu (198453), Yuxi Zhang (212307), Ming Chen (115604), Shuqiu Chen (4595818)   +4 more
core   +1 more source

Table_8_Roles of m5C RNA Modification Patterns in Biochemical Recurrence and Tumor Microenvironment Characterization of Prostate Adenocarcinoma.xlsx

, 2022
BackgroundProstate cancer is the second most common cancer with a high risk of biochemical recurrence (BCR) among men. Recently, 5-methylcytosine (m5C) modification has attracted more attention as a new layer of RNA post-transcriptional regulation. Hence,
Ruiji Liu (11975807), Zhipeng Xu (198453), Yuxi Zhang (212307), Ming Chen (115604), Shuqiu Chen (4595818)   +4 more
core   +1 more source