Results 111 to 120 of about 8,119 (209)

Table_2_Roles of m5C RNA Modification Patterns in Biochemical Recurrence and Tumor Microenvironment Characterization of Prostate Adenocarcinoma.docx

, 2022
BackgroundProstate cancer is the second most common cancer with a high risk of biochemical recurrence (BCR) among men. Recently, 5-methylcytosine (m5C) modification has attracted more attention as a new layer of RNA post-transcriptional regulation. Hence,
Ruiji Liu (11975807), Zhipeng Xu (198453), Yuxi Zhang (212307), Ming Chen (115604), Shuqiu Chen (4595818)   +4 more
core   +1 more source

Substrate selectivity of the human RNA m⁵C methyltransferase NSUN2. [PDF]

Nature
Canepa J, Ruiz-Arroyo VM, Schlamowitz NS, Nam Y.   +3 more
europepmc   +2 more sources

Table_1_Comprehensive Analysis of m5C Methylation Regulatory Genes and Tumor Microenvironment in Prostate Cancer.docx

, 2022
Background5-Methylcytidine (m5C) methylation is an emerging epigenetic modification in recent years, which is associated with the development and progression of various cancers.
Xin Gu (244758), Ming Zhan (27937), Jiahao Bao (12855575), Qing Yang (67856), Zhong Wang (132073), Yushan Liu (704070), Jiangyi Wang (6626843), Guopeng Yu (730431), Xinjuan Li (3599063), Bin Xu (10691), Shangqing Song (553292)   +10 more
core   +1 more source

Table_4_Comprehensive Analysis of m5C Methylation Regulatory Genes and Tumor Microenvironment in Prostate Cancer.docx

, 2022
Background5-Methylcytidine (m5C) methylation is an emerging epigenetic modification in recent years, which is associated with the development and progression of various cancers.
Xin Gu (244758), Ming Zhan (27937), Jiahao Bao (12855575), Qing Yang (67856), Zhong Wang (132073), Yushan Liu (704070), Jiangyi Wang (6626843), Guopeng Yu (730431), Xinjuan Li (3599063), Bin Xu (10691), Shangqing Song (553292)   +10 more
core   +1 more source

NSUN2-mediated RNA m5C modification drives multiple myeloma progression by enhancing the stability of HIP1 mRNA

Scientific Reports
RNA 5-methylcytosine (m5C) modification is a crucial epigenetic regulation, and aberrant m5C methylation is associated with the pathogenesis of certain cancers.
Yang Jiang, Jing Sun, Yuyan Chen, Lin Cheng, Saran Feng, Yan Wang, Congcong Sun   +6 more
doaj   +1 more source

Identification of m5C-related genes and subclusters in recurrent pregnancy loss

Journal of Assisted Reproduction and Genetics
Recurrent pregnancy loss (RPL), which occurs in 1-5% of couples and nearly half of the cases remain unexplained, is a complex condition influenced by multiple factors. Previous investigations have demonstrated the role of m5C-related genes (MRGs) in cancer prognosis and the significance of epigenetic modifications during pregnancy.
Huanmin Luo, Shuqing Li, Yuming Cao, Jinfeng Xu, Li Wang   +4 more
openaire   +2 more sources

5-Methylcytosine RNA modification and its roles in cancer and cancer chemotherapy resistance

Journal of Translational Medicine
Recent advancements in cancer therapies have improved clinical outcomes, yet therapeutic resistance remains a significant challenge because of its complex mechanisms.
Fang Li, Tingting Liu, Yajing Dong, Qianqian Gao, Rongzhu Lu, Zhiyong Deng   +5 more
doaj   +1 more source

The role of m5C, m1A and m7G modifications in tumors of urinary system

Frontiers in Cell and Developmental Biology
Malignant tumors of the urinary system, such as kidney cancer, bladder cancer, and prostate cancer, remain a significant challenge despite the various treatment options available. Identifying therapeutic targets for urological tumors is crucial due to the potential for recurrence and metastasis.
Wei Xue, Yuanyuan Zhao, Gong Zhang, Zhiyuan Li, Jixin Li, Xiang Fei   +5 more
openaire   +4 more sources

Lactylation-Boosted m5C RNA Modification Drives Choroidal Neovascularization

As a prevalent posttranscriptional RNA modification, N5-methylcytosine (m5C) plays a crucial role in a multitude of cellular responses and processes that govern RNA metabolism.
Yan Liu, Sipeng Zuo, Peiwei Chai, Linna Lu, Lin Li, Fuxiang Ye, Renbing Jia, Shengfang Ge, Jieling Tang, Sok, Xianqun Fan   +10 more
core   +1 more source

NSUN-Mediated m5C RNA Modification in Stem Cell Regulation

Cells
RNA modifications comprise a core epigenetic dimension of gene regulation; among these, N6-methyladenosine (m6A) and 5-methylcytosine (m5C) have been most intensively investigated. While the functions of m6A in stem cell biology have been well characterized, the contributions of m5C remain comparatively less well defined.
Jiin Moon, Hyohi Lee, Yeonju Jang, Seung-Kyoon Kim   +3 more
openaire   +2 more sources