Results 131 to 140 of about 11,326 (215)

Issue Information

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 5, May 2026.
wiley   +1 more source

m5C RNA methylation in cancer: from biological mechanism to clinical perspectives

European Journal of Medical Research
Cancer remains a significant global health threat, characterized by high morbidity and mortality rates. Despite advancements, numerous challenges persist in cancer treatment, underscoring the urgent need for novel therapeutic strategies. As a burgeoning area of cancer research, increasing evidence highlights the critical role of 5-methylcytosine (m5C ...
Fang Yuan, Yuxuan Xia, Zhen Huang, Huihui Gao, Yuqi Bian, Xiangqin Zhou   +5 more
openaire   +3 more sources

NSUN2/YBX1 promotes the progression of breast cancer by enhancing HGH1 mRNA stability through m5C methylation

Breast Cancer Research
Background RNA m5C methylation has been extensively implicated in the occurrence and development of tumors. As the main methyltransferase, NSUN2 plays a crucial regulatory role across diverse tumor types. However, the precise impact of NSUN2-mediated m5C
Xuran Zhang, Ke An, Xin Ge, Yuanyuan Sun, Jingyao Wei, Weihong Ren, Han Wang, Yueqin Wang, Yue Du, Lulu He, Ouwen Li, Shaoxuan Zhou, Yong Shi, Tong Ren, Yun-gui Yang, Quancheng Kan, Xin Tian   +16 more
doaj   +1 more source

Transcriptome-wide RNA 5-methylcytosine profiles of human iPSCs and iPSC-derived cardiomyocytes

Scientific Data
Cardiac regenerative therapy has recently progressed by reprogramming somatic cells into induced pluripotent stem cells (iPSCs) and advanced by large-scale differentiation-derived cardiomyocytes (hiPSC-CMs).
Szu-Ying Chen, Yi-Hsien Fang, Chen-Yu Huang, Jou-Hsien Wu, Yan-Shen Shan, Yen-Wen Liu, Po-Hsien Huang   +6 more
doaj   +1 more source

NSUN4-mediated m5C RNA methylation protects retinal cells against excitotoxic injury via the SHH signaling pathway. [PDF]

PLoS One
Li Y, Li D, Geng C, Wei R, Duan Y.
europepmc   +1 more source

Emerging roles of RNA N5-methylcytosine modification in reproductive physiology and gynecological diseases. [PDF]

Epigenetics
Lv F, Jin Y, Yu S, Yang X, Xia S, Ye X, Zhao Q, Hu Y, Zheng A, Wu Y, Tong J.   +10 more
europepmc   +1 more source

m5C: Novel Diagnostic and Drug Repurposing Targets for Nonalcoholic Steatohepatitis. [PDF]

Int J Genomics
Chen S, Duan R, Qiu J, Lei Z, Chen W, Li X.   +5 more
europepmc   +1 more source

Enhancing plant antiviral responses and productivity through the elimination of m⁵C methyltransferase. [PDF]

Sci Adv
Jiang Y, Liu P, Zhang M, Yong B, Yin J, Chen L, Shi C, Li P, Guo Y, Hu H, Feng L, Chen L, Zhang T, Liu J, Zhong K, Zhou X, Chen F, Chen J, Yang J.   +18 more
europepmc   +1 more source

Expanding the diversity of DNA base modifications with N 6-methyldeoxyadenosine [PDF]

, 2016
Kate D. Meyer, Samie R. Jaffrey
core   +1 more source

Deep learning model and omics screening highlight angiotensinogen as a 5-methylcytosine (m⁵C) regulated mediator of tumor-microenvironment communication in liver cancer. [PDF]

Front Immunol
Pang H, Wang L, Li Y, Zhou Y.
europepmc   +1 more source