Results 141 to 150 of about 7,626 (175)

Study of m5C as a regulator of mRNA stability

openaire   +1 more source

Some of the next articles are maybe not open access.

Related searches:

mRNA m5C inhibits adipogenesis and promotes myogenesis by respectively facilitating YBX2 and SMO mRNA export in ALYREF-m5C manner

Cellular and Molecular Life Sciences, 2022
Although 5-methylcytosine (m5C) has been identified as a novel and abundant mRNA modification and associated with energy metabolism, its regulation function in adipose tissue and skeletal muscle is still limited. This study aimed at investigating the effect of mRNA m5C on adipogenesis and myogenesis using Jinhua pigs (J), Yorkshire pigs (Y) and their ...
Xinxia Wang, Yongxi Yao, Xing Liao
exaly   +3 more sources

Staem5: A novel computational approach for accurate prediction of m5C site [PDF]

Molecular Therapy - Nucleic Acids, 2021
5-Methylcytosine (m5C) is an important post-transcriptional modification that has been extensively found in multiple types of RNAs. Many studies have shown that m5C plays vital roles in many biological functions, such as RNA structure stability and metabolism.
Fuyi Li, Quan Zou, Cangzhi Jia
exaly   +5 more sources

Emerging Role of RNA m5C Modification in Cardiovascular Diseases

Journal of Cardiovascular Translational Research, 2022
Epitranscriptomics is the emerging field of research that comprises the study of epigenetics changes in RNAs. Progressing development in the field of epigenetics has helped to manage and comprehend human diseases. RNA methylation regulates all aspects of RNA functions, which are involved in the pathogenesis of human diseases.
Arumugam Paramasivam
exaly   +3 more sources

Trans-m5C: A transformer-based model for predicting 5-methylcytosine (m5C) sites

Methods
5-Methylcytosine (m5C) plays a pivotal role in various RNA metabolic processes, including RNA localization, stability, and translation. Current high-throughput sequencing technologies for m5C site identification are resource-intensive in terms of cost, labor, and time. As such, there is a pressing need for efficient computational approaches.
Haitao Fu
exaly   +4 more sources

Recent insights into RNA m5C methylation modification in hepatocellular carcinoma

Biochimica Et Biophysica Acta: Reviews on Cancer
RNA 5-methylcytosine (m5C) methylation involves the addition of a methyl (-CH3) group to the cytosine (C) base within an RNA molecule, forming the m5C modification. m5C plays a role in numerous essential biological processes, including the regulation of RNA stability, nuclear export, and protein translation.
Mingyu He
exaly   +3 more sources

m5C mRNAs on the move

Nature Reviews Molecular Cell Biology, 2019
Cytosine methylation (m5C) in mRNAs is important for their transport to distant tissues in plants.
openaire   +2 more sources

The emerging role of m5C modification in viral infection

Virology
5-Methylcytosine (m5C) modification is a dynamic and reversible post-transcriptional process that has garnered significant attention due to its regulatory role in viral infections and host innate immune responses. Advances in m5C detection technologies have spurred research into its influence on viral infection pathways.
Jincheng Li, Leiliang Zhang
openaire   +2 more sources

YccW is the m5C Methyltransferase Specific for 23S rRNA Nucleotide 1962

Journal of Molecular Biology, 2008
Methylation at the 5-position of cytosine [m(5)C (5-methylcytidine)] occurs at three RNA nucleotides in Escherichia coli. All these modifications are at highly conserved nucleotides in the rRNAs, and each is catalyzed by its own m(5)C methyltransferase enzyme.
Purta, Elzbieta, O'Connor, Michelle, Bujnicki, Janusz M, Douthwaite, Stephen   +3 more
openaire   +2 more sources