Results 31 to 40 of about 21,524 (239)
Transcriptome-wide m6A methylation in natural yellow leaf of Catalpa fargesii
Frontiers in Plant Science, 2023 N6-methyladenosine (m6A) is the most abundant internal modification in eukaryotic messenger RNA, and involved in various biological processes in plants. However, the distribution features and functions of mRNA m6A methylation have been poorly explored in
Yu Zhang +9 more
doaj +1 more source
An association study of m6A methylation with major depressive disorder
BMC Psychiatry, 2023 Abstract Objective To find the relationship between N6-methyladenosine (m6A) genes and Major Depressive Disorder (MDD). Methods Differential expression of m6A associated genes between normal and MDD samples was ...
Ying Li +8 more
openaire +3 more sources
Detecting m6A methylation regions from Methylated RNA Immunoprecipitation Sequencing
Bioinformatics, 2021 AbstractMotivationThe post-transcriptional epigenetic modification on mRNA is an emerging field to study the gene regulatory mechanism and their association with diseases. Recently developed high-throughput sequencing technology named Methylated RNA Immunoprecipitation Sequencing (MeRIP-seq) enables one to profile mRNA epigenetic modification ...
Zhenxing Guo 0001 +4 more
openaire +2 more sources
Frontiers in Immunology, 2021 N6-methyladenosine (m6A) methylation is one of the most common modifications of RNA in eukaryotic cells, and is mainly regulated by m6A methyltransferases (writers), m6A demethylases (erasers), and m6A binding proteins (readers).
Liting Guo +5 more
doaj +1 more source
Emerging role of m6A methylation modification in ovarian cancer [PDF]
Cancer Cell International, 2021 Abstractm6A (N6-methyladenosine) methylation, a well-known modification in tumour epigenetics, dynamically and reversibly fine tunes the entire process of RNA metabolism. Aberrant levels of m6A and its regulators, which can predict the survival and outcomes of cancer patients, are involved in tumorigenesis, metastasis and resistance. Ovarian cancer (OC)
Lin-Lin Chang +6 more
openaire +3 more sources
Frontiers in Oncology, 2019 N6-methyladenosine (m6A) is the most common form of mRNA modification, and is dynamically regulated by the m6A RNA methylation regulators. However, little is known about m6A in gastric cancer. The aim of this work is to investigate the effects of m6A RNA
Yunshu Su, Jinqi Huang, Jichang Hu
doaj +1 more source
High-throughput m6A-seq reveals RNA m6A methylation patterns in the chloroplast and mitochondria transcriptomes of Arabidopsis thaliana. [PDF]
PLoS ONE, 2017 This study is the first to comprehensively characterize m6A patterns in the Arabidopsis chloroplast and mitochondria transcriptomes based on our open accessible data deposited in NCBI's Gene Expression Omnibus with GEO Series accession number of GSE72706.
Zegang Wang +6 more
doaj +1 more source
Genomics, Proteomics & Bioinformatics, 2023 As the most pervasive epigenetic marker present on mRNAs and long non-coding RNAs (lncRNAs), N6-methyladenosine (m6A) RNA methylation has been shown to participate in essential biological processes.
Bowen Song +8 more
doaj +1 more source
Role of m6A Methylation in the Occurrence and Development of Heart Failure
Frontiers in Cardiovascular Medicine, 2022 N6-methyladenosine (m6A) RNA methylation is one of the most common epigenetic modifications in RNA nucleotides. It is known that m6A methylation is involved in regulation, including gene expression, homeostasis, mRNA stability and other biological ...
Shaowei Fan, Yuanhui Hu
doaj +1 more source
Journal of Hematology & Oncology, 2022 The tumor microenvironment (TME), which is regulated by intrinsic oncogenic mechanisms and epigenetic modifications, has become a research hotspot in recent years.
Fusheng Zhang +8 more
doaj +1 more source