Results 201 to 210 of about 836,621 (308)

YTHDF1-Mediated m6A Modification of NREP Promotes Corneal Fibrosis via TGF-β-Smad Signaling. [PDF]

Invest Ophthalmol Vis Sci
Guan Y, Jing Y, Yang S, Yan X, Li X.
europepmc   +1 more source

Epigenomic Cascades Across Organs in Metabolic Dysfunction–Associated Steatotic Liver Disease: New Therapeutic Horizons

Obesity Reviews, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is the most common chronic liver disorder worldwide, affecting approximately one‐third of the population and increasing the risk of severe hepatic and cardiovascular complications.
Shurui Yang, Zhongyu Huang, Sanchun Tan, Fengxia Liang, Li Chen   +4 more
wiley   +1 more source

Exosomal delivery of METTL3 promotes M1 macrophage polarization by inducing miR-155-5p maturation via m6A modification. [PDF]

Ann Med
Wu X, Gong H, Zhang J, Yu L, Yan X, Pan W, Liu C.   +6 more
europepmc   +1 more source

DNA methylome responses to biotic and abiotic stress in Arabidopsis thaliana: A multi‐study analysis

Plant Biology, EarlyView.
Sixteen Arabidopsis thaliana Whole‐Genome Bisulfite Sequencing datasets have been analysed to reveal common and stress‐specific DNA methylation responses. Although global methylation levels remained stable, specific DMRs varied according to the type of stress and genomics context.
R. Behl, J. J. Gallo‐Franco, R. R. Hazarika, Z. Zhang, F. Wilming, J. P. Schnitzler, C. Lindermayr, F. Johannes   +7 more
wiley   +1 more source

m6A Modification of ATOX1 Inhibits Acute Myeloid Leukemia Progression by Promoting Cuproptosis. [PDF]

Cancer Res Commun
Peng J, Fu X, Li S, Hu C, Zhao X, Peng J.   +5 more
europepmc   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Integrative genomic and functional analysis of RAB3B in lung adenocarcinoma: associations with m6A modification and ceRNA networks. [PDF]

Front Pharmacol
Liu XS, Chen X, Wang N, Cheng ZM, Xie YC, Jiang T, Pei ZJ.   +6 more
europepmc   +1 more source

Understanding Exosomes in Hair Regeneration

Periodontology 2000, EarlyView.
Abstract Background Alopecia is a prevalent condition correlated with significant psychosocial challenges, while contemporary treatments exhibit variable efficacy, require extended use, and may cause adverse effects. This review aimed to comprehensively assess exosome‐mediated interventions as a novel cell‐free regenerative approach for hair ...
Paras Ahmad, Catherine Davies, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Mettl3-Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS. [PDF]

Adv Sci (Weinh)
Zhu F, Li H, Li X, Du C, Wang T, Zhou X, Xie X, Shao Y, Huang Y, Hu Y, Guo X, Zhu B, Yu S, Zhang X, Zhao B.   +14 more
europepmc   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source