Results 91 to 100 of about 24,501 (174)
The macroautophagy machinery in endo- and exocytosis
, 2017 Macroautophagy and the autophagy-related gene (Atg) machinery execute during their canonical function cytoplasmic constituent degradation in lysosomes. This canonical function contributes to pathogen restriction and intracellular antigen presentation on ...
Münz, Christian
core +1 more source
Morbus Crohn--a disease of failing macroautophagy in the immune system? [PDF]
, 2009 Mutations in genes involved in macroautophagy have been found to be associated with Morbus Crohn, also called Crohn's disease (CD), an inflammatory bowel disease.
Meixlsperger, S, Münz, C
core +1 more source
Beclin 1-Mediated Autophagy Is Potentiated by an Interaction with the Neuronal Adaptor FE65
BiologyAutophagy is a vital cellular pathway in eukaryotic cells, including neurons, where it plays significant roles in neurodevelopment and maintenance. A crucial step in autophagy is the formation of the class III phosphatidylinositol 3-kinase complex 1 ...
Wai Wa Ray Chan +4 more
doaj +1 more source
, 2012 Programmed cell death can occur through two separate pathways caused by treatment of Saccharomyces cerevisiae with acetic acid (AA-PCD), which differ from one another essentially with respect to their sensitivity to N-acetylcysteine (NAC) and to the role
Antonacci L +5 more
core +1 more source
, 2011 Macroautophagy is a cellular process that sequesters cytoplasmic content into autophagosomes for subsequent degradation. Precise regulation of macroautophagy ensures cell survival, with either excessive or insufficient level of macroautophagy leading to ...
Wong, Siu Lun
core
Macroautophagy, alpha-synuclein and dopamine neurotransmission: implications for Parkinsonâs disease
, 2017 Parkinsonâs disease (PD) is an incurable neurological disease characterised by impairment of motor function, death of substantia nigra pars compacta (SNc) dopamine (DA) neurons and accumulation of the protein α-synuclein. Macroautophagy, a major process
Benjamin Henry Mcleod Hunn
core
Morbus Crohn—a disease of failing macroautophagy in the immune system? [PDF]
, 2017 Mutations in genes involved in macroautophagy have been found to be associated with Morbus Crohn, also called Crohn's disease (CD), an inflammatory bowel disease.
Meixlsperger, Sonja, Münz, Christian
core
Sphingolipids in macroautophagy
, 2008 Sphingolipids are constituents of biological membranes. Ceramide and sphingosine 1-phosphate (S1P) also act as second messengers and are part of a rheostat system, in which ceramide promotes cell death and growth arrest, and S1P induces proliferation and
T. Levade +7 more
core +2 more sources
Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta,and Bcl-2.
, 2007 : Macroautophagy is an evolutionary conserved lysosomal pathway involved in the turnover of cellular macromolecules and organelles. In spite of its essential role in tissue homeostasis, the molecular mechanisms regulating mammalian macroautophagy are ...
CAMPANELLA, Michelangelo +20 more
core +1 more source
Immunohistochemical analysis of macroautophagy : recommendations and limitations
, 2013 : Transmission electron microscopy (TEM) is an indispensable standard method to monitor macroautophagy in tissue samples. Because TEM is time consuming and not suitable for daily routine, many groups try to identify macroautophagy in tissue by ...
Martinet, Wim +4 more
core