Results 61 to 70 of about 2,256 (152)
Mitochondrial ceramide-rich macrodomains functionalize Bax upon irradiation. [PDF]
PLoS ONE, 2011 BACKGROUND:Evidence indicates that Bax functions as a "lipidic" pore to regulate mitochondrial outer membrane permeabilization (MOMP), the apoptosis commitment step, through unknown membrane elements.
Hyunmi Lee +14 more
doaj +1 more source
ITM2B Truncation Promotes Migrasome Formation to Accelerate Renal Cell Carcinoma Growth
Advanced Science, Volume 13, Issue 4, 19 January 2026.This study identifies truncated ITM2B as a regulator of migrasome formation in renal cell carcinoma (RCC) cells. The ITM2B truncation not only facilitates migrasome formation by recruiting TSPAN4, but also sorts active caspase‐7 into migrasomes. The internalization of active caspase‐7‐enriched migrasomes by macrophages stimulates IL‐6 secretion to ...
Qi‐tao Chen +10 more
wiley +1 more source
Viral macrodomains are promising antiviral targets that counteract host ADP-ribosylation-mediated antiviral responses in mammals. However, their role in dual-host viruses within the mosquito vector remains largely unknown.
Jared Nigg +7 more
core +2 more sources
Journal of the American Ceramic Society, Volume 109, Issue 1, January 2026.In BiFeO3‐based lead‐free ceramics, ferroelectric polarization is suppressed by a polishing‐induced surface damage layer through the inhibition of Bi3⁺ off‐centering and nanoscale domain formation. Upon thermal annealing, the damaged layer is relaxed, Bi3⁺ displacement is restored, and nanoscale domains are reactivated, resulting in the recovery of the
Sangwook Kim, Hyunwook Nam, Hae In Choi
wiley +1 more source
Tropical Medicine &International Health, Volume 31, Issue 1, Page 49-57, January 2026.ABSTRACT Introduction Female genital schistosomiasis is a condition with a complex diagnosis and severe consequences such as infertility. In the absence of a reliable biomarker, in endemic settings the World Health Organization recommends colposcopy as a diagnostic tool for the detection of female genital schistosomiasis lesions.
Pia Rausche +22 more
wiley +1 more source
Highly Virulent Getah Virus Subgroup GIII‐c Emerging in Pigs in China
Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.Getah virus (GETV) is an emerging mosquito‐borne zoonotic alphavirus that poses a threat to multiple animal species, particularly pigs, and carries significant public health implications. Nevertheless, the molecular evolution and pathogenicity of circulating GETV strains in China remain incompletely defined.
Zhaoying Xiang +9 more
wiley +1 more source
A brief timeline of the discovery of macrodomain functions.
, 2018 Significant advances in the macrodomain field starting from the initial identification of “X-domains” in coronaviruses by Lee et al. in 1991 [4] to the present. Findings are listed in bold followed by relevant citations.
Diane E. Griffin (306426) +2 more
core +1 more source
Small, Volume 21, Issue 39, October 2, 2025.Unscreened high‐density polarons are discovered in a metallic WO3 (001) 2DEG, stabilized by surface oxygen vacancies and c(2 × 2) reconstruction. ARPES and STM/STS reveal polaron formation and ordering, supported by first‐principles calculations. This work opens new avenues for exploring collective polaron phenomena, including bipolaron interactions ...
Gyubin Lee +9 more
wiley +1 more source
, 2022 James Fraser's presentation at the monthly [virtual] Antiviral Drug Discovery (AViDD) Open Science Forum on 19 October 2022. His talk focuses on finding new ligands to the SARS CoV 2 Macrodomain using Fragments, Neutrons, and Entropy. Public datasets
Fraser, James
core +1 more source
Calcium regulation of muscle spindle mechanosensory afferent function
Experimental Physiology, Volume 110, Issue 10, Page 1457-1472, October 1, 2025.Abstract Extracellular calcium is crucial for the normal function of muscle spindle sensory afferents. They express multiple calcium buffering proteins. Extracellular calcium is essential for recycling of synaptic‐like vesicles (SLVs) in the terminals and for the stretch‐evoked inward calcium current of the receptor potential.
Anna Simon +5 more
wiley +1 more source