Results 61 to 70 of about 4,884 (228)

Single-nucleotide resolution detection of Topo IV cleavage activity in the Escherichia coli genome with Topo-Seq

open access: yesFrontiers in Microbiology, 2023
Topoisomerase IV (Topo IV) is the main decatenation enzyme in Escherichia coli; it removes catenation links that are formed during DNA replication. Topo IV binding and cleavage sites were previously identified in the E.
Dmitry Sutormin   +3 more
doaj   +1 more source

The role of ADP-ribosylation in regulating DNA interstrand crosslink repair [PDF]

open access: yes, 2016
ADP-ribosylation by ADP-ribosyltransferases (ARTs) has a wellestablished role in DNA strand break repair by promoting enrichment of repair factors at damage sites through ADP-ribose interaction domains. Here, we exploit the simple eukaryote Dictyostelium
Ahel, Ivan   +10 more
core   +4 more sources

Characterization of a Distinct Plasma Membrane Macrodomain in Differentiated Adipocytes [PDF]

open access: yesJournal of Biological Chemistry, 2002
Caveolae are small invaginations of the cell surface that are abundant in mature adipocytes. A recent study (Kanzaki, M., and Pessin, J. E. (2002) J. Biol. Chem. 277, 25867-25869) described novel caveolin- and actin-containing structures associated with the adipocyte cell surface that contain specific signaling proteins.
Parton, R. G.   +4 more
openaire   +3 more sources

Computational Investigations of Traditional Chinese Medicinal Compounds against the Omicron Variant of SARS-CoV-2 to Rescue the Host Immune System

open access: yesPharmaceuticals, 2022
Macrodomain-I of the NSP3 (non-structural protein 3) is responsible for immune response hijacking in the SARS-CoV-2 infection known as COVID-19. In the omicron variant (B.1.1.529), this domain harbors a new mutation, V1069I, which may increase the ...
Ziad Tareq Naman   +4 more
doaj   +1 more source

Visualization of poly(ADP-ribose) bound to PARG reveals inherent balance between exo- and endo-glycohydrolase activities [PDF]

open access: yes, 2013
Poly-ADP-ribosylation is a post-translational modification that regulates processes involved in genome stability. Breakdown of the poly(ADP-ribose) (PAR) polymer is catalysed by poly(ADP-ribose) glycohydrolase (PARG), whose endo-glycohydrolase activity ...
Ahel, Ivan   +10 more
core   +2 more sources

Dielectric behavior and phase transition in [111]-oriented PIN–PMN–PT single crystals under dc bias [PDF]

open access: yesJournal of Advanced Dielectrics, 2014
Temperature and electric field dependences of the dielectric behavior and phase transition for [111]-oriented 0.23PIN–0.52PMN–0.25PT (PIN-PMN–0.25PT) and 0.24PIN–0.43PMN–0.33PT (PIN–PMN–0.33PT) single crystals were investigated over a temperature range ...
Yuhui Wan   +6 more
doaj   +1 more source

Gene silencing and large-scale domain structure of the E. coli genome

open access: yes, 2012
The H-NS chromosome-organizing protein in E. coli can stabilize genomic DNA loops, and form oligomeric structures connected to repression of gene expression.
Lagomarsino, Marco Cosentino   +2 more
core   +2 more sources

Bacterial Chromosome Organization and Segregation [PDF]

open access: yes, 2018
If fully stretched out, a typical bacterial chromosome would be nearly 1 mm long, approximately 1,000 times the length of a cell. Not only must cells massively compact their genetic material, but they must also organize their DNA in a manner that is ...
Badrinarayanan, Anjana   +2 more
core   +1 more source

Correction: Mitochondrial Ceramide-Rich Macrodomains Functionalize Bax upon Irradiation

open access: yesPLOS ONE, 2015
The authors would like to correct Fig 5, as errors were introduced in the preparation of this figure for publication. In Fig 5D[b], the image for the Light fraction Bak Western blot and the numbering of the fractions are incorrect. The authors have provided a corrected version of Fig 5 here. Fig 5 Ceramide induces formation of a mitochondrial
Lee, Hyunmi   +14 more
openaire   +4 more sources

Structure of macrodomain walls in polytwinned magnets

open access: yesJournal of Applied Physics, 2002
We propose a microscopic approach to the studies of magnetic configurations in hard magnets which may be conveniently used for nanoscale systems; the microstructure of the magnet is easily and naturally included in the calculations. This approach is applied to find the structure of macrodomain walls in polytwinned magnets of the CoPt family ...
Belashchenko, Kirill D.   +1 more
openaire   +2 more sources

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