Results 11 to 20 of about 1,227,852 (247)

Cellular Mechanotransduction: From Tension to Function [PDF]

Frontiers in Physiology, 2018
Living cells are constantly exposed to mechanical stimuli arising from the surrounding extracellular matrix (ECM) or from neighboring cells. The intracellular molecular processes through which such physical cues are transformed into a biological response
Fabiana Martino, Fabiana Martino, Fabiana Martino, Ana R. Perestrelo, Vladimír Vinarský, Vladimír Vinarský, Stefania Pagliari, Giancarlo Forte, Giancarlo Forte, Giancarlo Forte   +9 more
doaj   +4 more sources

Cell Mechanotransduction With Piconewton Forces Applied by Optical Tweezers [PDF]

Frontiers in Cellular Neuroscience, 2018
Mechanical stresses are always present in the cellular environment and mechanotransduction occurs in all cells. Although many experimental approaches have been developed to investigate mechanotransduction, the physical properties of the mechanical ...
Fabio Falleroni, Vincent Torre, Vincent Torre, Vincent Torre, Dan Cojoc   +4 more
doaj   +2 more sources

Tailoring Cellular Function: The Contribution of the Nucleus in Mechanotransduction [PDF]

Frontiers in Bioengineering and Biotechnology, 2021
Cells sense a variety of different mechanochemical stimuli and promptly react to such signals by reshaping their morphology and adapting their structural organization and tensional state.
Fabrizio A. Pennacchio, Paulina Nastały, Paulina Nastały, Alessandro Poli, Paolo Maiuri   +4 more
doaj   +2 more sources

The Role of Connections Between Cellular and Tissue Mechanical Elements and the Importance of Applied Energy in Mechanotransduction in Cancerous Tissue

Biomolecules
In the presence of cellular mutations and impaired mechanisms of energy transmission to the attached cells and tissues, excess energy is available to upregulate some of the mechanotransduction pathways that maintain cell and tissue structure and function.
Frederick H. Silver
doaj   +2 more sources

Molecular and cellular analysis of topography-induced mechanotransduction [PDF]

, 2010
Edited Abstract: Mechanotransduction is the process by which cells convert mechanical stimuli into an adaptive gene- and protein-level response, via signalling cascades or direct physical effects of the cytoskeleton on the nucleus, and appropriate ...
McNamara, Laura Elizabeth
core   +7 more sources

FAK-mediated mechanotransduction in skeletal regeneration [PDF]

, 2007
The majority of cells are equipped to detect and decipher physical stimuli, and then react to these stimuli in a cell type-specific manner. Ultimately, these cellular behaviors are synchronized to produce a tissue response, but how this is achieved ...
Kim Jae-Beom, Jill A Helms, Jennifer A Currey, Leucht Philipp, Helms, Jill A., Kim, Jae-Beom, Jae-Beom Kim, Leucht, Philipp, Currey Jennifer A., Brunski John, Helms Jill A., Currey, Jennifer A., Philipp Leucht, Brunski, John, John Brunski   +14 more
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Mechanotransduction in fibroblasts [PDF]

, 2011
Response to mechanical stress is important for tissue homeostasis, tissue architecture and muscle regeneration. All cells of an organism are subject to at least one of three types of mechanical stress: compression, shear stress or tension.
Brosig, Michaela
core   +1 more source

αV-Integrins Are Required for Mechanotransduction in MDCK Epithelial Cells [PDF]

, 2013
The properties of epithelial cells within tissues are regulated by their immediate microenvironment, which consists of neighboring cells and the extracellular matrix (ECM).
Muller, Daniel J, Myllymäki, Satu M., Jens Friedrichs, Aki Manninen (221960), Matlin, Karl S., Daniel J. Muller (2509858), Manninen, Aki, Myllymäki Satu M., Manninen Aki, Jose V Moyano, Strohmeyer, Nico; id_orcid, Teräväinen, Terhi P, Muller Daniel J., Terhi P. Teräväinen (447383), Jens Friedrichs (447385), Muller, Daniel J., Satu M Myllymäki, Engler, Adam J., Friedrichs Jens, Chuanyue Wu (196653), Satu M. Myllymäki (447384), Strohmeyer, Nico, Nico Strohmeyer (447386), Karl S. Matlin (447388), Moyano, Jose V, Teräväinen, Terhi P., Terhi P Teräväinen, Karl S Matlin, Chuanyue Wu, Wu, Chuanyue, Moyano, Jose V., Strohmeyer Nico, Myllymäki, Satu M, Aki Manninen, Daniel J Muller, Jose V. Moyano (447387), Matlin Karl S., Wu Chuanyue, Moyano Jose V., Nico Strohmeyer, Matlin, Karl S, Friedrichs, Jens, Teräväinen Terhi P.   +42 more
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Modulation of cell-matrix adhesions to affect mechanotransduction [PDF]

, 2010
In cultured fibroblasts three types of cell-matrix adhesion with specific cellular localization and protein composition can be distinguished: focal complexes, focal adhesions and fibrillar adhesions.
Lutz, Roman
core   +1 more source

Biophysical Tools to Study Cellular Mechanotransduction

Bioengineering, 2017
The cell membrane is the interface that volumetrically isolates cellular components from the cell’s environment. Proteins embedded within and on the membrane have varied biological functions: reception of external biochemical signals, as membrane ...
Ismaeel Muhamed, Farhan Chowdhury, Venkat Maruthamuthu   +2 more
doaj   +1 more source