Neurosurgical diseases—including brain tumors, hemorrhage/trauma, ischemia, infection, epilepsy, and spinal cord injury—share convergent neuro-immune mechanisms.
Zheng Hu +10 more
doaj +1 more source
Morphology of the glymphatic and meningeal lymphatic structures of the bottlenose dolphin
In humans and mice, the glymphatic system, critical for central nervous system (CNS) health, relies on cardiorespiratory coupling, but has not yet been investigated in a diving mammal that routinely experiences apnea, bradycardia, and peripheral vasoconstriction.
Pabst, D. Ann +11 more
openaire +3 more sources
Impaired meningeal lymphatic drainage in Listeria monocytogenes infection
Previous studies have demonstrated an association between lymphatic vessels and diseases caused by bacterial infections. Listeria monocytogenes (LM) bacterial infection can affect multiple organs, including the intestine, brain, liver and spleen, which can be fatal.
Jian Feng +16 more
openaire +3 more sources
The glymphatic system (GS) functions as a critical pathway for waste clearance from the brain, facilitating soluble protein and metabolite drainage. Recently, GS dysfunction has emerged as a potential contributor to migraine pathophysiology.
Meng-fan Yang +6 more
doaj +1 more source
Meningeal lymphatics in aging and Alzheimer’s disease [PDF]
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A Review on The Glymphatic System and Meningeal Lymphatics
The maintenance of neuronal homeostasis within the central nervous system (CNS) requires the efficient removal of metabolic waste products and neurotoxic proteins. Historically, the CNS was considered devoid of a conventional lymphatic system, relying solely on passive diffusion for solute clearance. This paradigm shifted with the identification of the
openaire +1 more source
Visualising and semi-quantitatively measuring brain fluid pathways, including meningeal lymphatics, in humans using widely available MRI techniques. [PDF]
Sennfält S +9 more
europepmc +1 more source
Assessment of Meningeal Lymphatics in the Parasagittal Dural Space: A Prospective Feasibility Study Using Dynamic Contrast-Enhanced Magnetic Resonance Imaging. [PDF]
Joo B, Park M, Ahn SJ, Suh SH.
europepmc +1 more source
Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy. [PDF]
Da Mesquita S +30 more
europepmc +1 more source
THE RE-DISCOVERY OF DURAL (MENINGEAL) LYMPHATICS: AMNESIA OR AMBITION?
In 2015 the discovery of meningeal (dural) lymphatics was announced to much fanfare. The journal Science named this the second most important discovery of the year! Yet, they had actually been well described two and a quarter centuries earlier, in Italy, England and Holland.
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