Results 71 to 80 of about 3,252 (154)
Interaction Between Peripheral Cytokines and Central Neuroinflammation in Temporal Lobe Epilepsy
[18F]DPA‐714 PET/MRI revealed significantly increased uptake in ipsilateral temporal lobe structures of TLE patients. Ipsilateral hippocampal SUVR positively correlated with disease duration and seizure frequency. Serum cytokine profiling showed elevated IL‐17 and IFN‐γ and decreased IL‐2, IL‐4, and IL‐10 levels in TLE patients, but no significant ...
Heyu Zhang +13 more
wiley +1 more source
The dysfunction of microglia in the development of diabetes is associated with various diabetic complications, while traditional insulin therapy is insufficient to rapidly restore the function of microglia.
Shaojun Liu +5 more
doaj +1 more source
Reply to: The Physical Foundation of CSF‐IVIM
Magnetic Resonance in Medicine, EarlyView.
Yoshitaka Bito +4 more
wiley +1 more source
In a 100‐patient memory‐clinic cohort, DTI‐ALPS was evaluated along with diffusion and microstructural metrics. DTI‐ALPS correlated strongly with mode of anisotropy and orientation dispersion index, and moderately with T1/FLAIR ratio and diamagnetic susceptibility, indicating that DTI‐ALPS mainly reflects white‐matter diffusion complexity rather than ...
Luca Sacchi +14 more
wiley +1 more source
Bundle structures inside the deep cervical lymphatic vessels of mice
The lymphatic system plays a crucial role in immune function and the removal of cellular waste. Recent studies have highlighted the presence of primo vessels (PVs) inside lymphatic vessels, distinct from conventional lymphatic tissues, yet their ...
Joonyoung Shin, Sungchul Kim
doaj +1 more source
Intraventricular hemorrhage is one of the most fatal forms of brain injury that is a common complication of premature infants. However, the therapy of this type of hemorrhage is limited, and new strategies are needed to reduce hematoma expansion. Here we
Dongyu Li +18 more
doaj +1 more source
This review delineates the multifaceted roles of natural killer (NK) cells in the central nervous system, spanning direct cytolysis, immunoregulation, and crosstalk with the brain microenvironment. We evaluate the translational potential and challenges of NK cell immunotherapies for a spectrum of neurological conditions.
Kaihang Deng, Wai Po Chong
wiley +1 more source
We integrated DCE‐MRI‐based dural drainage function indicators (DDFIs) that reflect meningeal lymphatic vessels (mLVs) function into XGBoost models to predict the prognosis of intracranial malignant tumors. In a 2.5‐year follow‐up cohort of 100 patients, DDFIs remarkably improved the model's predictive performance, with a more significant enhancement ...
Lusen Ran +14 more
wiley +1 more source
Network Biology: Current Status, Applications, Challenges, and Future Prospects
Network biology integrates molecular interaction, intracellular regulatory, single‐cell and multicellular, microbial and host–microbiome, disease, and interorgan networks across biological scales. Perturbation models, multiomics, spatial profiling, computational inference, mechanistic modeling, and AI enable dynamic network reconstruction and causal ...
Xinmeng Li +7 more
wiley +1 more source

