Results 11 to 20 of about 23,950 (217)
Hepatology, EarlyView., 2022 Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince +30 more
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The mevalonate pathway in C. elegans [PDF]
Lipids in Health and Disease, 2011 The mevalonate pathway in human is responsible for the synthesis of cholesterol and other important biomolecules such as coenzyme Q, dolichols and isoprenoids. These molecules are required in the cell for functions ranging from signaling to membrane integrity, protein prenylation and glycosylation, and energy homeostasis. The pathway consists of a main
Rauthan Manish, Pilon Marc
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Mevalonate Biosynthesis in Plants
Critical Reviews in Biochemistry and Molecular Biology, 1999 (1999). Mevalonate Biosynthesis in Plants. Critical Reviews in Biochemistry and Molecular Biology: Vol. 34, No. 2, pp. 107-122.
Bach, Thomas J. +4 more
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A move in response to starvation
eLife, 2021 When a yeast cell runs out of fuel, it can increase the flux through a central metabolic pathway by simply changing the location of an enzyme.
Rebecca Martina Fausten, Maria Bohnert
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Management of Mevalonate Kinase Deficiency: A Pediatric Perspective
Frontiers in Immunology, 2020 Background: Mevalonate kinase deficiency (MKD) is an inborn error of metabolism leading to a syndrome characterized by recurrent inflammation. This clinically manifests itself as fever and can be accompanied by gastrointestinal symptoms, oral ulcers ...
Jerold Jeyaratnam, Joost Frenkel
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Biomolecules, 2021 Mevalonate Kinase Deficiency (MKD) is a rare inborn disease belonging to the family of periodic fever syndromes. The MKD phenotype is characterized by systemic inflammation involving multiple organs, including the nervous system.
Erika Rimondi +5 more
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Effect of ethanol on cholesterol and bile acid metabolism
Journal of Lipid Research, 1972 Ethanol feeding increased significantly levels of hepatic esterified cholesterol and serum free and esterified cholesterol in rats. Incorporation of intraperitoneally administered [14C]acetate into cholesterol was significantly increased.
A.F. Lefèvre, L.M. DeCarli, C.S. Lieber
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Molecules, 2021 Globally, Alzheimer’s disease (AD) is one of the most prevalent age-related neurodegenerative disorders associated with cognitive decline and memory deficits due to beta-amyloid deposition (Aβ) and tau protein hyperphosphorylation. To date, approximately
Rajib Das +7 more
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Journal of Lipid Research, 1982 Yields of (14)CO(2) from [2-(14)C]mevalonate and [5-(14)C]mevalonate have been used by others to estimate the activity of the non-sterol-forming pathway, also called the mevalonate shunt pathway, and yields of (14)C in sterols have been used to estimate ...
P S Brady +4 more
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Determination of mevalonate in blood plasma in man and rat. Mevalonate “tolerance” tests in man.
Journal of Lipid Research, 1979 A method is described for the determination of mevalonate in ultrafiltrates of blood plasma. The method depends on the phosphorylation of mevalonate with [gamma-32P]ATP and mevalonate kinase to 5-[32P]phosphomevalonate, and the subsequent isolation of ...
G Popják +5 more
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