Results 11 to 20 of about 24,078 (213)

Mevalonate Biosynthesis in Plants

open access: yesCritical Reviews in Biochemistry and Molecular Biology, 1999
(1999). Mevalonate Biosynthesis in Plants. Critical Reviews in Biochemistry and Molecular Biology: Vol. 34, No. 2, pp. 107-122.
Bach, Thomas J.   +4 more
openaire   +4 more sources

Influx of cholesterol into plasma in rabbits with fasting hyperbetalipoproteinemia

open access: yesJournal of Lipid Research, 1974
New Zealand white rabbits exhibited as much as a threefold increase in plasma cholesterol but no change in hepatic cholesterol when fasted for 7–9 days.
H.C. Klauda, D.B. Zilversmit
doaj   +1 more source

Mevalonate Metabolism in Immuno-Oncology

open access: yesFrontiers in Immunology, 2017
Immuno-oncology not only refers to the multifaceted relationship between our immune system and a developing cancer but also includes therapeutic approaches that harness the body’s immune system to fight cancer.
Georg Gruenbacher, Martin Thurnher
doaj   +1 more source

A move in response to starvation

open access: yeseLife, 2021
When a yeast cell runs out of fuel, it can increase the flux through a central metabolic pathway by simply changing the location of an enzyme.
Rebecca Martina Fausten, Maria Bohnert
doaj   +1 more source

Management of Mevalonate Kinase Deficiency: A Pediatric Perspective

open access: yesFrontiers in Immunology, 2020
Background: Mevalonate kinase deficiency (MKD) is an inborn error of metabolism leading to a syndrome characterized by recurrent inflammation. This clinically manifests itself as fever and can be accompanied by gastrointestinal symptoms, oral ulcers ...
Jerold Jeyaratnam, Joost Frenkel
doaj   +1 more source

Mevalonate Kinase Deficiency and Squalene Synthase Inhibitor (TAK-475): The Balance to Extinguish the Inflammation

open access: yesBiomolecules, 2021
Mevalonate Kinase Deficiency (MKD) is a rare inborn disease belonging to the family of periodic fever syndromes. The MKD phenotype is characterized by systemic inflammation involving multiple organs, including the nervous system.
Erika Rimondi   +5 more
doaj   +1 more source

Effect of ethanol on cholesterol and bile acid metabolism

open access: yesJournal of Lipid Research, 1972
Ethanol feeding increased significantly levels of hepatic esterified cholesterol and serum free and esterified cholesterol in rats. Incorporation of intraperitoneally administered [14C]acetate into cholesterol was significantly increased.
A.F. Lefèvre, L.M. DeCarli, C.S. Lieber
doaj   +1 more source

Role of Withaferin A and Its Derivatives in the Management of Alzheimer’s Disease: Recent Trends and Future Perspectives

open access: yesMolecules, 2021
Globally, Alzheimer’s disease (AD) is one of the most prevalent age-related neurodegenerative disorders associated with cognitive decline and memory deficits due to beta-amyloid deposition (Aβ) and tau protein hyperphosphorylation. To date, approximately
Rajib Das   +7 more
doaj   +1 more source

Evidence for an underestimation of the shunt pathway of mevalonate metabolism in slices of livers and kidneys from fasted rats and rats in diabetic ketosis

open access: yesJournal of Lipid Research, 1982
Yields of (14)CO(2) from [2-(14)C]mevalonate and [5-(14)C]mevalonate have been used by others to estimate the activity of the non-sterol-forming pathway, also called the mevalonate shunt pathway, and yields of (14)C in sterols have been used to estimate ...
P S Brady   +4 more
doaj   +1 more source

Urinary clearance and metabolism of mevalonate by the isolataed perfused rat kidney.

open access: yesJournal of Lipid Research, 1981
The urinary excretion and the incorporation into lipids of R[3-14C]mevalonate was investigated in isolated rat kidneys perfused with physiological concentration sof the substrate (80-500 pmol/ml).
H Brunengraber   +3 more
doaj   +1 more source

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