Results 121 to 130 of about 15,720 (202)

Roles of the negative regulatory loop MUC4-miR-210-3p in pancreatic carcinogenesis and and chemoresistance

open access: yes, 2022
Contexte : l'adénocarcinome pancréatique (PDAC) est un cancer mortel dontle pronostic est extrêmement sombre. La mucine membranaire MUC4 estnéoexprimée dans les lésions néoplasiques pancréatiques précoces et est associéeà la progression du PDAC et à la chimiorésistance.
openaire   +1 more source

Evaluation of microRNA-10a and microRNA-210 as Biomarkers in Sepsis Patients With Acute Kidney Injury

open access: yesInternational Journal of Nephrology
Conclusion: The study’s findings revealed a significant increase in miR-210-3p expression in sepsis patients with AKI, indicating its potential as a promising biomarker for determining AKI.
Hani Susianti   +6 more
doaj   +1 more source

Targeting EZH2 in Cancer: From Molecular Mechanisms to Clinical Translation

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
The abnormal overexpression or gain‐of‐function mutations of EZH2 play a significant role in cancer occurrence and progression, highlighting the importance and potential of EZH2 as a cancer biomarker. Therefore, screening for effective and safe small‐molecule inhibitors, degraders, and natural compounds targeting EZH2 through preclinical cancer models ...
Xi Zhong   +4 more
wiley   +1 more source

Homo luzonensis and the role of homoplasy in the morphology of hominin insular species

open access: yesCladistics, Volume 42, Issue 3, Page 286-316, June 2026.
Abstract Homo luzonensis lived during the upper Pleistocene in the northern Philippines, east of the Wallace line. The few specimens attributed to this species show a mosaic of plesiomorphies for the genus Homo and apomorphies found in upper Pleistocene Homo species.
Pierre Gousset   +4 more
wiley   +1 more source

Hepatocellular Carcinoma Cell-Secreted Exosomal MicroRNA-210 Promotes Angiogenesis In Vitro and In Vivo

open access: yesMolecular Therapy: Nucleic Acids, 2018
We previously found that 19 microRNAs (miRNAs) significantly increased in the sera of hepatocellular carcinoma (HCC) patients. Here, we evaluated whether these miRNAs were secreted by HCC cells and contributed to tumor angiogenesis. High level of miR-210-
Xue-Jia Lin   +6 more
doaj   +1 more source

Developmental expression of Ap‐Vas proteins in aphids and flies reveals their evolutionary roles in insects

open access: yesInsect Molecular Biology, Volume 35, Issue 3, Page 217-231, June 2026.
Duplication of vas genes is universally observed in aphids, and phylogenetic analysis indicates that this event predates the divergence of Aphididae and Phylloxeridae. Ap‐vas1 is germline‐specific, whereas Ap‐vas2–4 exhibit somatic expression, indicating functional divergence during aphid embryogenesis.
Gee‐Way Lin   +4 more
wiley   +1 more source

Identification of Differently Expressed miRNAs and Genes between Benign Prostatic Hyperplasia and Prostate Cancer [PDF]

open access: yesAdvanced Ultrasound in Diagnosis and Therapy
Objective MicroRNAs (miRNAs) play important roles in various diseases’ development and progression. The aim of this study is to identify the differently expressed miRNAs (DEmiRNAs) and differently expressed genes (DEGs) between BPH and PCa.
Yuqing Huang, MD, Cui Lei, BS, Xinyu Zhao, PhD, Jing Xiao, PhD, Xian-Quan Shi, PhD
doaj   +1 more source

Mechanoluminescence of a Ba4Si6O16:Eu2+, Ho3+‐Containing Glass‐Ceramic: Experiments Under Different Loading Modes and Modeling

open access: yesphysica status solidi (a), Volume 223, Issue 10, 22 May 2026.
A glass‐ceramic from the BaO‐SiO2 chemical system emits light under mechanical loading provided it was submitted to UV irradiation prior to mechanical loading. This phenomenon is known as elasto‐mechanoluminescnence and, in the present case, it occurs thanks to the incorporation of a few percents of europium and holmium and an original synthesis route ...
Alexis Duval   +6 more
wiley   +1 more source

Secreted miR-210-3p, miR-183-5p and miR-96-5p reduce sensitivity to docetaxel in prostate cancer cells. [PDF]

open access: yesCell Death Discov, 2023
Canovai M   +10 more
europepmc   +1 more source

TEAD1 Enhances Exosome Secretion and Promotes Exosome‐Mediated Tissue Regeneration

open access: yesAdvanced Science, Volume 13, Issue 25, 4 May 2026.
TEAD1 functions as a crucial molecular switch regulating exosome secretion in various cell types. TEAD1 enhances exosome secretion by upregulating key proteins associated with exosome secretion, including RAB11, CD9, and SNAP23. This study reveals a novel role for TEAD1 in regulating exosome secretion and tissue regeneration, particularly in diabetic ...
Yan Pu   +9 more
wiley   +1 more source

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