Results 1 to 10 of about 4,115 (133)

miR-590-5p Overexpression Alleviates β-Amyloid-Induced Neuron Damage via Targeting Pellino-1. [PDF]

Anal Cell Pathol (Amst), 2022
Alzheimer’s disease (AD) is one common degenerative disorder. However, the effects of miR-590-5p on AD and the mechanism on modulation of AD development were unclear.
Shang L, Peng T, Chen X, Yan Z, Wang J, Gao X, Chang C.   +6 more
europepmc   +4 more sources

Exosomal miR-590-5p in Serum as a Biomarker for the Diagnosis and Prognosis of Gastric Cancer. [PDF]

Front Mol Biosci, 2021
The purpose of this study is to explore the expression of miRNA-590-5p, an exosome of gastric cancer (GC), and to evaluate the suitability of miR-590-5p, an exosome with its own clinical characteristics. Serum samples from 168 gastric cancer patients and
Zheng GD, Xu ZY, Hu C, Lv H, Xie HX, Huang T, Zhang YQ, Chen GP, Fu YF, Cheng XD.   +9 more
europepmc   +5 more sources

miR-590-5p/Tiam1-mediated glucose metabolism promotes malignant evolution of pancreatic cancer by regulating SLC2A3 stability. [PDF]

Cancer Cell Int, 2023
Background T lymphoma invasion and metastasis 1 (Tiam1) is a tumor related gene that specifically activates Rho-like GTPases Rac1 and plays a critical role in the progression of various malignancies.
Liu Y, Jin A, Quan X, Shen X, Zhou H, Zhao X, Lin Z.   +6 more
europepmc   +4 more sources

Prognostic value of circ_0000043/miR-590-5p in cervical cancer and regulation of tumor progression. [PDF]

Discov Oncol
Objective To investigate the prognostic value of circ_0000043 in cervical cancer (CC) and its involvement in the modulation of patients’ prognostic progression.
Zhu Y, Shi X, Zhang S, Cui H, Wu B.
europepmc   +4 more sources

Circular RNA CircEPB41L2 Functions as Tumor Suppressor in Hepatocellular Carcinoma Through Sponging miR-590-5p. [PDF]

Cancer Manag Res, 2021
Feng Chen,1,2 Lei He,2,3 Liman Qiu,2,3 Yang Zhou,2,3 Zhenli Li,2,3 Geng Chen,2,3 Fuli Xin,2,3 Xiuqing Dong,2,3 Haipo Xu,2,3 Gaoxiong Wang,4 Jingfeng Liu,2,3 Zhixiong Cai2,3 1College of Life Science, Fujian Agriculture and Forestry University, Fuzhou ...
Chen F, He L, Qiu L, Zhou Y, Li Z, Chen G, Xin F, Dong X, Xu H, Wang G, Liu J, Cai Z.   +11 more
europepmc   +5 more sources

LncRNA ZEB1-AS1 knockdown alleviates oxidative low-density lipoprotein-induced endothelial cell injury via the miR-590-5p/HDAC9 axis. [PDF]

Cent Eur J Immunol, 2021
Oxidative low-density lipoprotein (ox-LDL) is thought to induce vascular endothelial cell injury, which contributes to the aetiopathogenesis of atherosclerosis (AS).
Zhong J, Cheng B, Yang L, Li G, Yuan Y, Luo G, Shu Z, Jiang H.   +7 more
europepmc   +2 more sources

miR-590-5p mediates mitochondrial respiration, proliferation, and apoptosis in thyroid carcinoma cells via fibroblast growth factor receptor substrate 2. [PDF]

Arch Endocrinol Metab
Objective: Thyroid carcinoma (TC) is the most common cancer of the endocrine system. Dysregulation of microRNA-590-5p (miR-590-5p) has been associated with various malignancies. Targeting mitochondrial respiration is beneficial in treating TC. This study
Wang P, Hou X, Sun W, Chen J, Cao Y, Cheng H.   +5 more
europepmc   +3 more sources

Circular RNA circ_0020123 promotes non-small cell lung cancer progression by sponging miR-590-5p to regulate THBS2. [PDF]

Cancer Cell Int, 2020
Background The incidence and death rate of non-small cell lung cancer (NSCLC) in China ranks the first among the malignant tumors. Circular RNA (circRNA) was reported to be involved in the progression of NSCLC.
Wang L, Zhao L, Wang Y.
europepmc   +2 more sources

Linc02381 Exacerbates Rheumatoid Arthritis Through Adsorbing miR-590-5p and Activating the Mitogen-Activated Protein Kinase Signaling Pathway in Rheumatoid arthritis-fibroblast-like synoviocytes. [PDF]

Cell Transplant, 2020
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease. New evidence suggested that linc02381 suppressed colorectal cancer progression by regulating PI3 K signaling pathway, but the role of linc02381 in other diseases, such as RA, remains ...
Wang J, Zhao Q.
europepmc   +2 more sources

Peroxisome Proliferator-Activated Receptor-γ Antagonizes LOX-1-Mediated Endothelial Injury by Transcriptional Activation of miR-590-5p. [PDF]

PPAR Res, 2019
Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is one of the major receptors expressed on the endothelium of arterial wall with a key role in endothelial dysfunction and the development of atherosclerosis.
Xu L, Zhao G, Zhu H, Wang S, Sun A, Zou Y, Ge J.   +6 more
europepmc   +2 more sources