Results 31 to 40 of about 4,115 (133)

Knockdown of lncRNA NUTM2A-AS1 inhibits lung adenocarcinoma cell viability by regulating the miR-590-5p/METTL3 axis.

open access: yesOncol Lett, 2021
Lung adenocarcinoma (LUAD) is the leading cause of cancer-related mortality worldwide. Long non-coding RNA (lncRNA) NUT family member 2A antisense RNA 1 (NUTM2A-AS1) is dysregulated in LUAD; however, its role in this disease remains unclear. The present study aimed to identify the underlying molecular mechanism of the effect of lncRNA NUTM2A-AS1 in ...
Wang J, Zha J, Wang X.
europepmc   +4 more sources

Potential Value of Circular RNA circTBC1D4 in Gastrointestinal Stromal Tumors

open access: yesJournal of Immunology Research, 2022
Aims. To explore the expression of circular RNA (circRNA) in gastrointestinal stromal tumors. Background. Gastrointestinal stromal tumors (GIST) are mainly distributed in the stomach and small intestine.
null Chunyan-Zou   +7 more
doaj   +1 more source

Non-coding RNA Activated by DNA Damage: Review of Its Roles in the Carcinogenesis

open access: yesFrontiers in Cell and Developmental Biology, 2021
Long intergenic non-coding RNA 00657 (LINC00657) or “non-coding RNA activated by DNA damage” (NORAD) is an extremely conserved and copious long non-coding RNA (lncRNA). This transcript has pivotal role in the preservation of genome integrity.
Soudeh Ghafouri-Fard   +5 more
doaj   +1 more source

Identification of potential microRNA diagnostic panels and uncovering regulatory mechanisms in breast cancer pathogenesis

open access: yesScientific Reports, 2022
Early diagnosis of breast cancer (BC), as the most common cancer among women, increases the survival rate and effectiveness of treatment. MicroRNAs (miRNAs) control various cell behaviors, and their dysregulation is widely involved in pathophysiological ...
Zahra Sharifi   +2 more
doaj   +1 more source

Signature of circulating microRNAs as potential biomarkers in vulnerable coronary artery disease. [PDF]

open access: yesPLoS ONE, 2013
AIMS: MicroRNAs (miRNAs) play important roles in the pathogenesis of cardiovascular diseases. Circulating miRNAs were recently identified as biomarkers for various physiological and pathological conditions.
Jingyi Ren   +8 more
doaj   +1 more source

Profil Ekspresi MikroRNA Kanker Payudara di Purwokerto

open access: yesJurnal Kesehatan Andalas, 2021
Penemuan metode deteksi dini kanker payudara secara sensitif, spesifik dan minimal invasif merupakan kunci dalam keberhasilan pengobatan. Hal ini dapat dilakukan menggunakan biomarker yang bersirkulasi dalam plasma darah yaitu mikroRNA.
Ari Dwi Nurasih   +2 more
doaj   +1 more source

Altered Expression of Specific MicroRNAs in Plasma of Aneurysmal Subarachnoid Hemorrhage Patients

open access: yesFrontiers in Neurology, 2022
BackgroundAneurysmal subarachnoid hemorrhage (aSAH) is a life-threatening condition with high disability and mortality. MicroRNAs (miRNAs) are reported to play a modulating role in aSAH.
Lina Zheng   +3 more
doaj   +1 more source

miR‑590‑5p suppresses osteosarcoma cell proliferation and invasion via targeting KLF5

open access: yesMolecular Medicine Reports, 2018
Recently, microRNA (miR)‑590‑5p has been shown to inhibit tumorigenesis in colorectal and breast cancer; however, its function in osteosarcoma (OS) requires further investigation. In the present study miR‑590‑5p expression was poorly expressed in OS samples and cell lines when compared with that observed in normal cells.
Wei, Cai   +4 more
openaire   +3 more sources

Discovery of Novel miRNAs in Colorectal Cancer: Potential Biological Roles and Clinical Utility

open access: yesNon-Coding RNA, 2023
Deregulated miRNAs are associated with colorectal cancer (CRC), with alterations depending on the tumor location. Novel tissue-specific miRNAs have been identified in different tumors and are associated with cancer.
Iael Weissberg Minutentag   +10 more
doaj   +1 more source

MicroRNA-590-5p antagonizes the inhibitory effect of high glucose on osteoblast differentiation by suppressing Smad7 in MC3T3-E1 cells

open access: yesJournal of International Medical Research, 2019
Objective MicroRNA-590-5p (miR-590-5p) has been reported to stimulate osteoblast differentiation; however, its effect in diabetic osteoporosis remains unknown.
Yinan Chen   +6 more
doaj   +1 more source

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