Results 71 to 80 of about 4,115 (133)

Serum and thyroid tissue level of let-7b and their correlation with TRAb in Graves’ disease

Journal of Translational Medicine, 2018
Background Abnormal microRNAs (miRNAs) were reported to be involved in the mechanism of Graves’ disease (GD). Dysregulated miRNAs may be overlapping in different cells and can be secreted to circulation.
Xinxin Chen, Fengjiao Huang, Yicheng Qi, Mengxi Zhou, Qinglei Yin, Ying Peng, Yulin Zhou, Guang Ning, Shu Wang   +8 more
doaj   +1 more source

Epigenetic Programming Through Breast Milk and Its Impact on Milk-Siblings Mating

Frontiers in Genetics, 2020
BackgroundThe epigenetic effects of transmission of certain regulatory molecules, such as miRNAs, through maternal milk on future generations, are still unknown and have not been fully understood yet.
Hasan Ozkan, Funda Tuzun, Serpil Taheri, Serpil Taheri, Peyda Korhan, Pınar Akokay, Osman Yılmaz, Nuray Duman, Erdener Özer, Esra Tufan, Abdullah Kumral, Yusuf Özkul, Yusuf Özkul   +12 more
doaj   +1 more source

Small Extracellular Vesicles From Human Amniotic Membrane Mesenchymal Stem Cells Rejuvenate Senescent β Cells and Cure Age‐Related Diabetes in Mice

Aging Cell, Volume 25, Issue 1, January 2026.
hAMSC‐sEVs rejuvenate β cells and improve glycaemic control via the miR‐21‐5p/IL‐6RA/STAT3/MCU axis, restoring mitochondrial Ca2+ homeostasis and insulin secretion in aged T2DM mice. ABSTRACT Targeting senescent pancreatic β‐cells represents a promising therapeutic avenue for age‐related diabetes; however, current anti‐senescence strategies often ...
Lei Xiao, Zicheng Zhang, Tong Li, Yuyin Jiang, Yuanxin Liu, Tingting Lv, Lianju Qin, Yunxia Zhu, Wei Tang   +8 more
wiley   +1 more source

A fluorescence lifetime separation approach for FLIM live‐cell imaging

Journal of Microscopy, Volume 301, Issue 1, Page 91-106, January 2026.
Abstract Fluorescence lifetime imaging microscopy (FLIM) translates the duration of excited states of fluorophores into lifetime information as an additional source of contrast in images of biological samples. This offers the possibility to separate fluorophores particularly beneficial in case of similar excitation spectra.
Cornelia Wetzker, Marcelo Leomil Zoccoler, Svetlana Iarovenko, Chukwuebuka William Okafornta, Anja Nobst, Hella Hartmann, Thomas Müller‐Reichert, Robert Haase, Gunar Fabig   +8 more
wiley   +1 more source

miR-590-5p regulates gastric cancer cell growth and chemosensitivity through RECK and the AKT/ERK pathway

OncoTargets and Therapy, 2016
The aim of this study was to determine the role of miRNA-590-5p in gastric cancer (GC) progression.Quantitative real-time polymerase chain reaction was performed to measure endogenous miR-590-5p levels in GC cells and tissues. Overexpression or knockdown of miR-590-5p in GC cells was performed by transfection with mimics or an inhibitor, respectively ...
Shen,Bo, Yu,Shaorong, Zhang,Yan, Yuan,Yuan, Li,Xiaoyou, Zhong,Jian, Feng,Jifeng   +6 more
openaire   +4 more sources

0D Cesium Lanthanide Chlorides: Spectroscopic Insights and Optical Properties for Emerging Optoelectronic Applications

Advanced Optical Materials, Volume 13, Issue 36, December 19, 2025.
Trivalent lanthanides or rare earth elements are positioning themselves as “critical and strategic minerals” due to their significance in securing technological supremacy in the modern world. At present, a huge demand of rare earth elements in numerous sectors is witnessed, such as optoelectronics, telecommunications, military systems, renewable energy,
Sheikh Jobe, Lamia Ali Siddig, Adel Najar, Na'il Saleh, Abbas Khaleel, Fathy M Hassan   +5 more
wiley   +1 more source

Upregulation of miR-133b and miR-328 in Patients With Atrial Dilatation: Implications for Stretch-Induced Atrial Fibrillation

Frontiers in Physiology, 2019
Atrial stretch and dilatation are common features of many clinical conditions predisposing to atrial fibrillation (AF). MicroRNAs (miRs) are emerging as potential molecular determinants of AF, but their relationship with atrial dilatation (AD) is poorly ...
Michela Masè, Michela Masè, Margherita Grasso, Laura Avogaro, Manuel Nicolussi Giacomaz, Elvira D’Amato, Francesco Tessarolo, Angelo Graffigna, Michela Alessandra Denti, Flavia Ravelli   +9 more
doaj   +1 more source

Temozolomide resistance in glioblastoma: a non-coding RNA viewpoint

Advances in Cancer Biology - Metastasis
As an imidazotetrazine derived from the alkylating substance dacarbazine, Temozolomide (TMZ) is commonly used as the routine chemotherapy for new cases of glioblastoma multiforme (GBM). It substantially improves the clinical outcome of patients.
Maryam Motallebinezhad, Ali Faravash, Mohammad Ghasemian, Zahra Tajik, Mohsen Ahmadi, Solat Eslami, Soudeh Ghafouri-Fard   +6 more
doaj   +1 more source

miRNA expression profiles of premalignant and malignant arsenic-induced skin lesions.

PLoS ONE, 2018
Arsenic, a naturally occurring element, contaminates the drinking water of over 200 million people globally. Chronic arsenic exposure causes multiple cancers including those originating from skin, lung and bladder, and is associated with liver, kidney ...
Laila Al-Eryani, Samantha F Jenkins, Vanessa A States, Jianmin Pan, Janine C Malone, Shesh N Rai, Susan Galandiuk, Ashok K Giri, J Christopher States   +8 more
doaj   +1 more source

miR-590-5p suppresses hepatocellular carcinoma chemoresistance by targeting YAP1 expressionResearch in context

EBioMedicine, 2018
Background: Resistance to chemotherapeutic treatment is a common phenomenon in cancers, especially in hepatocellular carcinoma (HCC). The Hippo signaling pathway has been demonstrated to play a role in tumor initiation, development, and progression. However, little is known about its roles in the HCC chemoresistance.
Minjiang Chen, Liming Wu, Jianfei Tu, Zhongwei Zhao, Xiaoxi Fan, Jianting Mao, Qiaoyou Weng, Xulu Wu, Li Huang, Min Xu, Jiansong Ji   +10 more
openaire   +1 more source