Results 81 to 90 of about 4,115 (133)

miRNA expression profile of vulvar squamous cell carcinoma and identification of the oncogenic role of miR-590-5p

Oncology Reports, 2015
MicroRNAs (miRNAs), a class of small non-coding RNA molecules, are associated with a variety of human cancers. Currently, little data are available regarding miRNA expression in vulvar squamous cell carcinoma (VSCC); the mechanism of action of miRNAs in VSCC still requires investigation.
Xiuhua, Yang, Xin, Wu
openaire   +3 more sources

Integrative bioinformatics analysis of miRNA and mRNA expression profiles and identification of associated miRNA-mRNA network in intracranial aneurysms

Non-coding RNA Research
Background: Intracranial aneurysms (IAs) represent protrusions in the vascular wall, with their growth and wall thinning influenced by various factors. These processes can culminate in the rupture of the aneurysm, leading to subarachnoid hemorrhage (SAH).
Dongxiao Xu, Ilgiz Gareev, Ozal Beylerli, Valentin Pavlov, Huang Le, Huaizhang Shi   +5 more
doaj   +1 more source

Long Non-Coding RNA Linc-USP16 Functions As a Tumour Suppressor in Hepatocellular Carcinoma by Regulating PTEN Expression

Cellular Physiology and Biochemistry, 2017
Background/Aims: Recent evidence has indicated the crucial regulatory roles of long non-coding RNAs (lncRNAs) in tumour biology. In hepatocellular carcinoma (HCC), aberrant expression of lncRNAs plays an essential role in HCC tumourigenesis. However, the
Jidong Sui, Xuejun Yang, Wenjing Qi, Kun Guo, Zhenming Gao, Liming Wang, Deguang Sun   +6 more
doaj   +1 more source

Prognostic and predictive microRNA panels for heart failure patients with reduced or preserved ejection fraction: a meta-analysis of Kaplan–Meier-based individual patient data

BMC Medicine
Background Cardiac troponins and natriuretic peptides are benchmark biomarkers for heart failure (HF) with reduced ejection fraction (HFrEF) but have limited prognostic performance for HF patients with preserved ejection fraction (HFpEF).
Reza Parvan, Victoria Becker, Milad Hosseinpour, Yousef Moradi, William E. Louch, Alessandro Cataliotti, Yvan Devaux, Michael Frisk, Gustavo Jose Justo Silva, AtheroNET COST Action CA21153   +9 more
doaj   +1 more source

Retracted: Circ-GTF2I/miR-590-5p Axis Aggravates Myocardial Ischemia-Reperfusion Injury by Regulating Kelch Repeat and BTB Domain-Containing Protein 7. [PDF]

Evid Based Complement Alternat Med, 2023
And Alternative Medicine EC.
europepmc   +1 more source

MicroRNA miR-590-5p inhibits breast cancer cell stemness and metastasis by targeting SOX2.

European review for medical and pharmacological sciences, 2017
SOX2 (Sry-related high-mobility box SOX-2) is a transcription factor, which is essential for maintaining the cancer cell stemness. However, the role of microRNAs targeting  SOX2 in cancer cell stemness remains unclear. We examined the effect of miR-590-5p, which targeted  SOX2, on the breast cancer cell stemness and metastasis.We predicted and screened
L, Zhou, L-C, Zhao, N, Jiang, X-L, Wang, X-N, Zhou, X-L, Luo, J, Ren   +6 more
openaire   +1 more source

Poster Session 3

Pregnancy, Volume 2, Issue S1, January 2026.
wiley   +1 more source

Differential Expression of Maternal Plasma microRNAs and Their Respective Gene Targets Can Predict Early Fetal Growth Restriction

Life
Fetal growth restriction (FGR) is a condition where the fetus does not reach its genetically predetermined size, affecting 1 in 10 pregnancies and contributing to up to 50% of all stillbirths before 34 weeks of gestation.
Emmanuel Kolawole, Aparna Duggirala, Oscar Gronow, Agnieszka Wisniewska, Jiamiao Hu, Bee Kang Tan   +5 more
doaj   +1 more source

lncRNA FTX promotes asthma progression by sponging miR-590-5p and upregulating JAK2.

American journal of translational research
The increased proliferation and migration of airway smooth muscle cells (ASMCs) are essential factors in the development of asthma. Long noncoding RNAs (lncRNAs) play key roles in the pathogenesis of various diseases, including asthma. A growing body of evidence indicates that lncRNA FTX regulates proliferation and migration in multiple cell types and ...
Yan, Shen, Gui, Yang, Songming, Zhuo, Hong, Zhuang, Sida, Chen   +4 more
openaire   +1 more source

NUTM2A-AS1 as a potential key regulator in cancer: unraveling its ceRNA networks and impact on tumor biology

European Journal of Medical Research
NUTM2A-AS1 is an emerging long noncoding RNA (lncRNA) that has garnered significant attention due to its multifaceted roles in cancer biology. As a member of the ceRNA network, NUTM2A-AS1 modulates gene expression by sequestering microRNAs, thereby ...
Negar Taghavi Pourianazar, Safa Radmehr, Zahra Ourang, Kaveh Jaseb, Alireza Asadi   +4 more
doaj   +1 more source