Results 101 to 110 of about 34,113 (275)
On the Regulation of Mitochondrial Fusion, Fission and Mitochondrial DNA
, 2020 Mitochondria are functionally and structurally fascinating organelles, well known for their role as the cellular powerhouse. Unlike other membrane bound organelles, mitochondria maintain their own genome (mtDNA), which is present in hundreds of copies per cell, packaged into nucleo-protein structures known as nucleoids.
openaire +2 more sources
Mitochondrial network complexity emerges from fission/fusion dynamics [PDF]
, 2018 Mitochondrial networks exhibit a variety of complex behaviors, including coordinated cell-wide oscillations of energy states as well as a phase transition (depolarization) in response to oxidative stress.
Zamponi, Emiliano +11 more
core +1 more source
Food Biomacromolecules, EarlyView.Bidirectional interactions between food‐derived sensory compounds, gut sensing and microbiota, host physiological feedback, and metabolite production within the food matrix collectively shape sensory perception, microbial dynamics, and metabolic health.
Mohammad Nazrul Islam Bhuiyan
wiley +1 more source
Impairing the Mitochondrial Fission and Fusion Balance: A New Mechanism of Neurodegeneration
, 2008 Mitochondrial dysfunction is a common characteristic of all neurodegenerative diseases. However, the cause of this dysfunction remains a mystery. Here, we discuss the potential role of mitochondrial fission and fusion in the onset and progression of ...
Ella Bossy-Wetzel +3 more
core +2 more sources
Mitochondrial dynamism and heart disease: changing shape and shaping change
EMBO Molecular Medicine, 2015 Mitochondria of adult cardiomyocytes appear hypo‐dynamic, lacking interconnected reticular networks and the continual fission and fusion observed in many other cell types.
Gerald W Dorn
doaj +1 more source
PLoS ONE, 2020 Mitochondrial fission and fusion play an important role not only in maintaining mitochondrial homeostasis but also in preserving overall cellular viability.
Rensu P Theart +4 more
doaj +1 more source
Restriction of trophic factors and nutrients induces PARKIN expression [PDF]
, 2011 Parkinson's disease (PD) is the most frequent neurodegenerative movement disorder and manifests at old age. While many details of its pathogenesis remain to be elucidated, in particular the protein and mitochondrial quality control during stress ...
Klinkenberg, Michael +11 more
core +1 more source
Mitochondrial dynamics in type 2 diabetes: Pathophysiological implications
Redox Biology, 2017 Mitochondria play a key role in maintaining cellular metabolic homeostasis. These organelles have a high plasticity and are involved in dynamic processes such as mitochondrial fusion and fission, mitophagy and mitochondrial biogenesis. Type 2 diabetes is
Susana Rovira-Llopis +5 more
doaj +1 more source
Quantitative characterization of mitochondrial fission and fusion events.
, 2014 (A) Thresholded images following the schematic described in Figure 2 segregates individual mitochondria to be tracked for identification of fission or fusion events.
William S. Hlavacek (101977) +4 more
core +1 more source
Endoplasmic reticulum stress induced by turbulence of mitochondrial fusion and fission was involved in stressed cardiomyocyte injury. [PDF]
J Cell Mol Med, 2023 Zhang S +8 more
europepmc +1 more source