Results 121 to 130 of about 36,753 (273)

Impairing the Mitochondrial Fission and Fusion Balance: A New Mechanism of Neurodegeneration

, 2008
Mitochondrial dysfunction is a common characteristic of all neurodegenerative diseases. However, the cause of this dysfunction remains a mystery. Here, we discuss the potential role of mitochondrial fission and fusion in the onset and progression of ...
Ella Bossy-Wetzel, Knott, Andrew B., Bossy-Wetzel, Ella, Andrew B. Knott   +3 more
core   +2 more sources

Mitochondrial fusion- and fission-related protein expression in the regulation of skeletal muscle mass. [PDF]

Physiol Rep, 2022
Nakano D, Machida S.
europepmc   +1 more source

Mitochondrial network complexity emerges from fission/fusion dynamics [PDF]

, 2018
Mitochondrial networks exhibit a variety of complex behaviors, including coordinated cell-wide oscillations of energy states as well as a phase transition (depolarization) in response to oxidative stress.
Zamponi, Emiliano, Orlando V. Billoni, Dante R. Chialvo, Nahuel Zamponi, Chialvo, Dante Renato, Sergio A. Cannas, Pablo R. Helguera, Billoni, Orlando Vito, Helguera, Pablo Rodolfo, Zamponi, Nahuel, Emiliano Zamponi, Cannas, Sergio Alejandro   +11 more
core   +1 more source

Mitochondrial fusion and fission: The fine-tune balance for cellular homeostasis. [PDF]

FASEB J, 2021
Adebayo M, Singh S, Singh AP, Dasgupta S.   +3 more
europepmc   +1 more source

Mitochondrial fission and fusion factors reciprocally orchestrate mitophagic culling in mouse hearts and cultured fibroblasts. [PDF]

, 2015
SummaryHow mitochondrial dynamism (fission and fusion) affects mitochondrial quality control is unclear. We uncovered distinct effects on mitophagy of inhibiting Drp1-mediated mitochondrial fission versus mitofusin-mediated mitochondrial fusion ...
Song M, Mihara K, Mihara, Katsuyoshi, Song, Moshi, Chen, Yun, Chen Y, Dorn GW 2nd, Dorn, Gerald W., SCORRANO, LUCA   +8 more
core   +1 more source

Quantitative characterization of mitochondrial fission and fusion events.

, 2014
(A) Thresholded images following the schematic described in Figure 2 segregates individual mitochondria to be tracked for identification of fission or fusion events.
William S. Hlavacek (101977), Laura M. Westrate (289571), Katie R. Martin (298384), Jeffrey P. MacKeigan (185626), Jeffrey A. Drocco (551725)   +4 more
core   +1 more source

Krüppel like factor 7 regulates mitochondrial dynamics balance in myocardial infarction

Communications Biology
Targeting the balance of mitochondrial fission and fusion can effectively alleviate the cardiac energy supply efficiency, to restore cardiac systolic dysfunction and reduce mortality.
Cao Wang, Fuxing Zhu, Lan Zhou, Situo Zhang, Ruiqi Wang, Hui Tian, Bosong Zhang, Jiahui Wu, Xiang Xu, Ruixian Jiang, Xiaolu Hou, Jian Liu, Weiming Tian   +12 more
doaj   +1 more source

Antisense Oligonucleotide-Mediated Silencing of Mitochondrial Fusion and Fission Factors Modulates Mitochondrial Dynamics and Rescues Mitochondrial Dysfunction. [PDF]

Nucleic Acid Ther, 2022
Garcia DA, Powers AF, Bell TA, Guo S, Aghajan M.   +4 more
europepmc   +1 more source

ZFP36L2 regulates myocardial ischemia/reperfusion injury and attenuates mitochondrial fusion and fission by LncRNA PVT1. [PDF]

Cell Death Dis, 2021
Wu F, Huang W, Tan Q, Guo Y, Cao Y, Shang J, Ping F, Wang W, Li Y.   +8 more
europepmc   +1 more source

Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis

iNew Medicine, EarlyView.
This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang, Rongyu Guo, Xiaojun Feng, Liqin Tang   +3 more
wiley   +1 more source