Frontiers in Physiology, 2016 It has been suggested that skeletal muscle mitochondria play a key role in high fat diet induced insulin resistance. Two opposite views are debated on mechanisms by which mitochondrial function could be involved in skeletal muscle insulin resistance.
Rosalba ePutti +3 more
doaj +1 more source
Syntaphilin Ubiquitination Regulates Mitochondrial Dynamics and Tumor Cell Movements. [PDF]
, 2018 Syntaphilin (SNPH) inhibits the movement of mitochondria in tumor cells, preventing their accumulation at the cortical cytoskeleton and limiting the bioenergetics of cell motility and invasion. Although this may suppress metastasis, the regulation of the
Agarwal, Ekta +11 more
core +1 more source
Novel Organelle‐Based Intracellular Immunity With Mechanistic and Therapeutic Implications
Barrier Immunity, EarlyView.A conceptual framework illustrating how PAMPs/DAMPs initiate barrier, innate, adaptive, and intracellular immune responses, with organelle‐based intracellular immunity serving as a central integrator linking metabolism, inflammatory signaling, and therapeutic interventions to restore immune homeostasis.
Keman Xu +9 more
wiley +1 more source
Endoplasmic reticulum stress induced by turbulence of mitochondrial fusion and fission was involved in stressed cardiomyocyte injury. [PDF]
J Cell Mol Med, 2023 Zhang S +8 more
europepmc +1 more source
Mitochondrial fission regulates germ cell differentiation by suppressing ROS-mediated activation of Epidermal Growth Factor Signaling in the Drosophila larval testis. [PDF]
, 2019 Mitochondria are essential organelles that have recently emerged as hubs for several metabolic and signaling pathways in the cell. Mitochondrial morphology is regulated by constant fusion and fission events to maintain a functional mitochondrial network ...
Jones, D Leanne, Sênos Demarco, Rafael
core +1 more source
Regulation of mitochondrial permeability transition pore by PINK1 [PDF]
, 2012 Background: Loss-of-function mutations in PTEN-induced kinase 1 (PINK1) have been linked to familial Parkinson’s disease, but the underlying pathogenic mechanism remains unclear.
Caballero, Erica +7 more
core +3 more sources
Food Biomacromolecules, EarlyView.Bidirectional interactions between food‐derived sensory compounds, gut sensing and microbiota, host physiological feedback, and metabolite production within the food matrix collectively shape sensory perception, microbial dynamics, and metabolic health.
Mohammad Nazrul Islam Bhuiyan
wiley +1 more source
Inhibition of KMO Ameliorates Myocardial Ischemia Injury via Maintaining Mitochondrial Fusion and Fission Balance. [PDF]
Int J Biol Sci, 2023 Lai Q +8 more
europepmc +1 more source
Regulation of Mitochondrial Dynamics by Proteolytic Processing and Protein Turnover
Antioxidants, 2018 The mitochondrial network is a dynamic organization within eukaryotic cells that participates in a variety of essential cellular processes, such as adenosine triphosphate (ATP) synthesis, central metabolism, apoptosis and inflammation.
Sumaira Ali, Gavin P. McStay
doaj +1 more source
Mitochondrial fusion- and fission-related protein expression in the regulation of skeletal muscle mass. [PDF]
Physiol Rep, 2022 Nakano D, Machida S.
europepmc +1 more source