Results 11 to 20 of about 40,537 (209)
Putative Structural and Functional Coupling of the Mitochondrial BKCa Channel to the Respiratory Chain. [PDF]
PLoS ONE, 2013 Potassium channels have been found in the inner mitochondrial membranes of various cells. These channels regulate the mitochondrial membrane potential, the matrix volume and respiration. The activation of these channels is cytoprotective.
Piotr Bednarczyk +5 more
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Scientific Reports, 2021 The activation of mitochondrial large conductance calcium-activated potassium (mitoBKCa) channels increases cell survival during ischemia/reperfusion injury of cardiac cells.
Shur Gałecka +4 more
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Postconditioning with D-limonene exerts neuroprotection in rats via enhancing mitochondrial activity
Türk Biyokimya Dergisi, 2023 The key component of neuroprotection after cerebral ischemia–reperfusion (I–R) injury is mitochondrial improvement. By focusing on the function of mitochondrial biogenesis and ATP-sensitive potassium (mK–ATP) channels and inflammatory responses, the ...
Zhang Leguo +5 more
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Membranes, 2023 In the inner mitochondrial membrane, several potassium channels that play a role in cell life and death have been identified. One of these channels is the ATP-regulated potassium channel (mitoKATP).
Milena Krajewska +3 more
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The Mitochondrial Routing of the Kv1.3 Channel
Frontiers in Oncology, 2022 Voltage-gated potassium channels control neuronal excitability and cardiac action potentials. In addition, these proteins are involved in a myriad of cellular processes.
Jesusa Capera +5 more
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Biomedicines, 2023 Modulation of mitochondrial K channels represents a pharmacological strategy to promote cardioprotective effects. Isothiocyanates emerge as molecules capable of releasing hydrogen sulfide (H2S), an endogenous pleiotropic gasotransmitter responsible for ...
Lorenzo Flori +10 more
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Identification of different subtypes of K(+) channels in the mitochondria of rat myometrium using K(+) channels modulators [PDF]
The Ukrainian Biochemical JournalPotassium ions affect Ca2+ transport in mitochondria, the magnitude of the electric potential on the inner mitochondrial membrane, metabolic processes in the matrix, and osmoregulation.
M. V. Rudnytska +3 more
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Cell & Bioscience, 2020 Background Openers of mitochondrial adenosine triphosphate-dependent potassium (mKATP) channels like diazoxide increase reactive oxygen species (ROS) production in cardiac cells and reduce Ca2+ elevations produced by ischemia–reperfusion, protecting the ...
Joice T. Gavali +3 more
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BK in Double-Membrane Organelles: A Biophysical, Pharmacological, and Functional Survey
Frontiers in Physiology, 2021 In the 1970s, calcium-activated potassium currents were recorded for the first time. In 10years, this Ca2+-activated potassium channel was identified in rat skeletal muscle, chromaffin cells and characterized in skeletal muscle membranes reconstituted in
Naileth González-Sanabria +4 more
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KCNMA1 encoded cardiac BK channels afford protection against ischemia-reperfusion injury. [PDF]
PLoS ONE, 2014 Mitochondrial potassium channels have been implicated in myocardial protection mediated through pre-/postconditioning. Compounds that open the Ca2+- and voltage-activated potassium channel of big-conductance (BK) have a pre-conditioning-like effect on ...
Ewa Soltysinska +20 more
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