Results 21 to 30 of about 38,197 (138)

New Mitochondrial Potassium Channels [PDF]

open access: yesBiophysical Journal, 2014
Mitochondrial potassium channels play an important role in cytoprotection. The following potassium channels have been described in the inner mitochondrial membrane: the ATP-regulated potassium channel, the large conductance calcium activated potassium channel, the voltage-gated potassium channel and the twin-pore domain TASK-3 potassium channel ...
Szewczyk, Adam   +4 more
openaire   +1 more source

Postconditioning with D-limonene exerts neuroprotection in rats via enhancing mitochondrial activity

open access: yesTürk Biyokimya Dergisi, 2023
The key component of neuroprotection after cerebral ischemia–reperfusion (I–R) injury is mitochondrial improvement. By focusing on the function of mitochondrial biogenesis and ATP-sensitive potassium (mK–ATP) channels and inflammatory responses, the ...
Zhang Leguo   +5 more
doaj   +1 more source

Pharmacological Characterization of a Recombinant Mitochondrial ROMK2 Potassium Channel Expressed in Bacteria and Reconstituted in Planar Lipid Bilayers

open access: yesMembranes, 2023
In the inner mitochondrial membrane, several potassium channels that play a role in cell life and death have been identified. One of these channels is the ATP-regulated potassium channel (mitoKATP).
Milena Krajewska   +3 more
doaj   +1 more source

The Mitochondrial Routing of the Kv1.3 Channel

open access: yesFrontiers in Oncology, 2022
Voltage-gated potassium channels control neuronal excitability and cardiac action potentials. In addition, these proteins are involved in a myriad of cellular processes.
Jesusa Capera   +5 more
doaj   +1 more source

Erucin Exerts Cardioprotective Effects on Ischemia/Reperfusion Injury through the Modulation of mitoKATP Channels

open access: yesBiomedicines, 2023
Modulation of mitochondrial K channels represents a pharmacological strategy to promote cardioprotective effects. Isothiocyanates emerge as molecules capable of releasing hydrogen sulfide (H2S), an endogenous pleiotropic gasotransmitter responsible for ...
Lorenzo Flori   +10 more
doaj   +1 more source

Mechanosensitivity of Mitochondrial Potassium Channels [PDF]

open access: yesBiophysical Journal, 2017
Mitochondria are known for their unique membrane architecture with the inner membrane folded into cristae. It is also known for long that mitochondria undergo drastic changes in volume. These volume changes depend on potassium fluxes. Influx via mitochondrial potassium channels (e.g.
Piotr Koprowski   +3 more
openaire   +1 more source

Mitochondrial potassium channels - an overview.

open access: yesPostepy biochemii, 2019
Mitochondria play a fundamental role in ATP synthesis within the majority of mammalian cells. Potassium channels present in the inner mitochondrial membrane are fine regulators of mitochondrial function, based on inner membrane K+ permeability. These channels are regulated by a plethora of factors and conditions in a way similar to plasma membrane ...
Adam, Szewczyk   +13 more
openaire   +3 more sources

The uniqueness of the plant mitochondrial potassium channel

open access: yesBMB Reports, 2013
The ATP-inhibited Plant Mitochondrial K(+) Channel (PmitoKATP) was discovered about fifteen years ago in Durum Wheat Mitochondria (DWM). PmitoKATP catalyses the electrophoretic K(+) uniport through the inner mitochondrial membrane; moreover, the co-operation between PmitoKATP and K(+)/H(+) antiporter allows such a great operation of a K(+) cycle to ...
PASTORE, DONATO   +3 more
openaire   +3 more sources

Mitochondrial potassium channels and reactive oxygen species [PDF]

open access: yesFEBS Letters, 2010
Pretreatment of tissues with potassium channel openers (KCO's) has been observed to be cytoprotective in a broad variety of insults. This phenomenon has been proposed to be intimately linked to activation of mitochondrial potassium channels which apparently modulate the mitochondrial production of reactive oxygen species (ROS).
Malinska, Dominika   +2 more
openaire   +2 more sources

Identification of different subtypes of K(+) channels in the mitochondria of rat myometrium using K(+) channels modulators [PDF]

open access: yesThe Ukrainian Biochemical Journal
Potassium ions affect Ca2+ transport in mitochondria, the magnitude of the electric potential on the inner mitochondrial membrane, metabolic processes in the matrix, and osmoregulation.
M. V. Rudnytska   +3 more
doaj   +1 more source

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