Database of all currently known mobile colistin resistance genes. [PDF]
Microbiol Resour AnnouncWe created a database of all currently known mobile colistin resistance genes and variants (n = 115). It contains accession numbers of the gene and protein sequences, mutations between the protein variants and the main proteins, and additional metadata ...
Rebelo AR, Hendriksen RS.
europepmc +4 more sources
Evolutionary drivers of mobile colistin resistance [PDF]
, 2023 Antibiotics are our strongest defence against disease causing bacteria. This makes the threat of widespread antibiotic resistance all the more concerning.
core +2 more sources
A Review of Resistance to Polymyxins and Evolving Mobile Colistin Resistance Gene (mcr) among Pathogens of Clinical Significance. [PDF]
Antibiotics (Basel), 2023 The global rise in antibiotic resistance in bacteria poses a major challenge in treating infectious diseases. Polymyxins (e.g., polymyxin B and colistin) are last-resort antibiotics against resistant Gram-negative bacteria, but the effectiveness of ...
Shahzad S, Willcox MDP, Rayamajhee B.
europepmc +5 more sources
First report of plasmid-mediated colistin resistance mcr-8.1 gene from a clinical Klebsiella pneumoniae isolate from Lebanon [PDF]
Antimicrobial Resistance and Infection Control, 2020 Colistin is considered as a last resort treatment for infections caused by multidrug-resistant Enterobacteriaceae. Plasmid-mediated mobile colistin resistance (mcr) genes contributed to the global spread of colistin resistance.
Tamara Salloum +5 more
doaj +2 more sources
Antibiotics, 2022 Background: A collection of human-epidemiologically unrelated S. enterica strains collected over a 3-year period (2016 to 2018) in Italy by the national surveillance Enter-Net Italia was analysed.
Daniela Fortini +8 more
doaj +2 more sources
Proposal for assignment of allele numbers for mobile colistin resistance (mcr) genes. [PDF]
J Antimicrob Chemother, 2018 The initial report of the mcr-1 (mobile colistin resistance) gene has led to many reports of mcr-1 variants and other mcr genes from different bacterial species originating from human, animal and environmental samples in different geographical locations.
Partridge SR +15 more
europepmc +8 more sources
The first human report of mobile colistin resistance gene, mcr-1, in Finland [PDF]
APMIS, 2022 Colistin resistance mediated by mobile mcr-1 gene has raised concern during the last years. After steep increase in mcr-1 reports, other mcr-gene variants (mcr-2 to mcr-5) have been revealed as well.
Lindholm L +6 more
core +9 more sources
Mobile colistin resistance gene mcr-5 in porcine Aeromonas hydrophila. [PDF]
J Antimicrob Chemother, 2018 Objectives: To characterize the mobile colistin resistance gene mcr-5 in Aeromonas hydrophila from backyard pigs in rural areas of China. Methods: Pig faecal samples from 194 households were directly tested for the presence of mcr-5 by PCR assay and the ...
Ma S +10 more
europepmc +5 more sources
Environmental mediation of colistin resistance in the African context. A systematic scoping review [PDF]
Journal of Global Antimicrobial ResistanceObjectives: The prevalence of antimicrobial resistance (AMR) among Gram-negative bacteria is a major global health concern. Resistance to last-resort antibiotics like colistin is particularly alarming.
Emmanuel Udochukwu Osisiogu +5 more
doaj +2 more sources
Emergence of Colistin-Resistant Acinetobacter junii in China
Antibiotics, 2022 The increasing number of multidrug-resistant Gram-negative bacteria presents a serious threat to global health. However, colistin-resistant Acinetobacter junii has rarely been reported. We identified a colistin-resistant A. junii clinical isolate, AJ6079,
Zhiren Wang +6 more
doaj +2 more sources