Results 31 to 40 of about 1,479 (165)
ANÁLISE CONFORMACIONAL DE COMPOSTOS DE BIGINELLI COM ATIVIDADE ANTINEOPLÁSICA
Eclética Química, 2018 Dihydropyrimidinones, such as monastrol and analogues, are heterocycles with known antineoplastic activity. Conformational analysis represents an important preliminary step in structure-activity correlation studies. Herein we describe the conformational
Marcelo Volpatto Marques +2 more
doaj +1 more source
Acrylamide neurotoxicity on the cerebrum of weaning rats
Neural Regeneration Research, 2015 The mechanism underlying acrylamide-induced neurotoxicity remains controversial. Previous studies have focused on acrylamide-induced toxicity in adult rodents, but neurotoxicity in weaning rats has not been investigated.
Su-min Tian +5 more
doaj +1 more source
Neural Regeneration Research, 2015 Ferumoxytol, an iron replacement product, is a new type of superparamagnetic iron oxide approved by the US Food and Drug Administration. Herein, we assessed the feasibility of tracking transplanted human adipose-derived stem cells labeled with ...
Yan Yin +5 more
doaj +1 more source
Dual pathway spindle assembly increases both the speed and the fidelity of mitosis [PDF]
, 2011 Roughly half of all animal somatic cell spindles assemble by the classical prophase pathway, in which the centrosomes separate ahead of nuclear envelope breakdown (NEBD).
Robert A. Cross +5 more
core +1 more source
Neural Regeneration Research, 2015 The Wnt/β-catenin signaling pathway plays a crucial role in neural development, axonal guidance, neuropathic pain remission and neuronal survival. In this study, we initially examined the effect of rapamycin on the Wnt/β-catenin signaling pathway after ...
Kai Gao +7 more
doaj +1 more source
Curcumin improves synaptic plasticity impairment induced by HIV-1gp120 V3 loop
Neural Regeneration Research, 2015 Curcumin has been shown to significantly improve spatial memory impairment induced by HIV-1 gp120 V3 in rats, but the electrophysiological mechanism remains unknown.
Ling-ling Shen +11 more
doaj +1 more source
Neural Regeneration Research, 2015 Microtubules have been identified as a powerful target for augmenting regeneration of injured adult axons in the central nervous system. Drugs that stabilize microtubules have shown some promise, but there are concerns that abnormally stabilizing ...
Peter W Baas, Andrew J Matamoros
doaj +1 more source
Neural Regeneration Research, 2015 In this report, we present the results of a single patient with optic neuropathy treated within the Stem Cell Ophthalmology Treatment Study (SCOTS). SCOTS is an Institutional Review Board approved clinical trial and is the largest ophthalmology stem cell
Jeffrey N Weiss +2 more
doaj +1 more source
Neural Regeneration Research, 2015 Cell therapy using stem cell transplantation against cerebral ischemia has been reported. However, it remains controversial regarding the optimal time for cell transplantation and the transplantation route.
Seyed Mojtaba Hosseini +4 more
doaj +1 more source
Comparison of the Effects of Monastrol and Oxomonastrol on Human Hepatoma Cell Line HepG2/C3A [PDF]
, 2017 Monastrol and its analog oxomonastrol differ by replacement of the sulfur atom present in monastrol to an oxygen atom in oxomonastrol. Monastrol inhibits the mitotic kinesin family member 11 (EG5), which has been studied for its potential use in cancer ...
Mantovani, Mario Sergio +11 more
core +1 more source