Results 61 to 70 of about 1,479 (165)

N-Propionylmannosamine stimulates axonal elongation in a murine model of sciatic nerve injury

open access: yesNeural Regeneration Research, 2015
Increasing evidence indicates that sialic acid plays an important role during nerve regeneration. Sialic acids can be modified in vitro as well as in vivo using metabolic oligosaccharide engineering of the N-acyl side chain.
Christian Witzel   +3 more
doaj   +1 more source

Eg5 and Diseases: From the Well‐Known Role in Cancer to the Less‐Known Activity in Noncancerous Pathological Conditions

open access: yesBiochemistry Research International, Volume 2024, Issue 1, 2024.
Eg5 is a protein encoded by KIF11 gene and is primarily involved in correct mitotic cell division. It is also involved in nonmitotic processes such as polypeptide synthesis, protein transport, and angiogenesis. The scientific literature sheds light on the ubiquitous functions of KIF11 and its involvement in the onset and progression of different ...
Alessia Ricci   +4 more
wiley   +1 more source

Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5

open access: yes, 2000
Monastrol, a cell-permeable small molecule inhibitor of the mitotic kinesin, Eg5, arrests cells in mitosis with monoastral spindles. Here, we use monastrol to probe mitotic mechanisms.
Mitchison, Timothy J.   +7 more
core   +1 more source

Biological conduits combining bone marrow mesenchymal stem cells and extracellular matrix to treat long-segment sciatic nerve defects

open access: yesNeural Regeneration Research, 2015
The transplantation of polylactic glycolic acid conduits combining bone marrow mesenchymal stem cells and extracellular matrix gel for the repair of sciatic nerve injury is effective in some respects, but few data comparing the biomechanical factors ...
Yang Wang   +4 more
doaj   +1 more source

Shrinkage of ipsilateral taste buds and hyperplasia of contralateral taste buds following chorda tympani nerve transection

open access: yesNeural Regeneration Research, 2015
The morphological changes that occur in the taste buds after denervation are not well understood in rats, especially in the contralateral tongue epithelium.
Yi-ke Li   +4 more
doaj   +1 more source

Effect of prolonged treatment with monastrol on cell viability.

open access: yes, 2015
Cells from AGS, HepG2, Lovo39, Du145, and HT29 cell lines, indicated at the lower left corner of each panel, were incubated for up to three days with various concentrations of monastrol, indicated on the right (0, 20, 50, 100, and 150μM).
Michal Hershfinkel (303795)   +3 more
core   +1 more source

Matrilin-2, an extracellular adaptor protein, is needed for the regeneration of muscle, nerve and other tissues

open access: yesNeural Regeneration Research, 2015
The extracellular matrix (ECM) performs essential functions in the differentiation, maintenance and remodeling of tissues during development and regeneration, and it undergoes dynamic changes during remodeling concomitant to alterations in the cell-ECM ...
Éva Korpos, Ferenc Deák, Ibolya Kiss
doaj   +1 more source

Phage display: development of nanocarriers for targeted drug delivery to the brain

open access: yesNeural Regeneration Research, 2015
The blood brain barrier represents a formidable obstacle for the transport of most systematically administered neurodiagnostics and neurotherapeutics to the brain.
Babak Bakhshinejad   +2 more
doaj   +1 more source

Human condensin function is essential for centromeric chromatin assembly and proper sister kinetochore orientation. [PDF]

open access: yesPLoS ONE, 2009
Condensins I and II in vertebrates are essential ATP-dependent complexes necessary for chromosome condensation in mitosis. Condensins depletion is known to perturb structure and function of centromeres, however the mechanism of this functional link ...
Alexander Samoshkin   +9 more
doaj   +1 more source

Strategies to avoid a missed diagnosis of co-occurring concussion in post-acute patients having a spinal cord injury

open access: yesNeural Regeneration Research, 2015
Research scientists and clinicians should be aware that missed diagnoses of mild-moderate traumatic brain injuries in post-acute patients having spinal cord injuries may approach 60-74% with certain risk factors, potentially causing clinical consequences
David S Kushner
doaj   +1 more source

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