Results 31 to 40 of about 113,465,300 (217)

Monocarboxylate transporter 1 and monocarboxylate transporter 4 in cancer-endothelial co-culturing microenvironments promote proliferation, migration, and invasion of renal cancer cells

open access: yesCancer Cell International, 2019
Background The Warburg effect demonstrates the importance of glycolysis in the development of primary and metastatic cancers. We aimed to explore the role of monocarboxylate transporter 1 (MCT1) and MCT4, two essential transporters of lactate, in renal ...
Chen Guo   +9 more
doaj   +1 more source

A TRAP transporter for pyruvate and other monocarboxylate 2-oxoacids in the cyanobacterium Anabaena sp. strain PCC 7120

open access: yes
In the cyanobacterium Anabaena sp. strain PCC 7120, open reading frames (ORFs) alr3026, alr3027, and all3028 encode a tripartite ATP-independent periplasmic transporter (TRAP-T).
Pernil R, Herrero A, Flores E
core   +5 more sources

Intestinal OCTN2- and MCT1-targeted drug delivery to improve oral bioavailability

open access: yesAsian Journal of Pharmaceutical Sciences, 2020
Various drug transporters are widely expressed throughout the intestine and play important roles in absorbing nutrients and drugs, thus providing high quality targets for the design of prodrugs or nanoparticles to facilitate oral drug delivery.
Gang Wang   +8 more
doaj   +1 more source

IMMUNOHISTOCHEMICAL EXPRESSION OF MONOCARBOXYLATE TRANSPORTER 1&4 IN TANYCYTE–LIKE CELLS OF THE SULCUS MEDIANUS ORGANUM

open access: yesThe Iraqi Journal of Medical Sciences, 2019
Background: Circumventricular organs (CVOs) are specialized structures border the brain ventricles and lack the blood-brain barrier. These CVOs are lined by specialized ependymal cells (ECs) called tanycyte.
Haider F. Jawad   +2 more
doaj   +6 more sources

Monocarboxylate transporter 8 deficiency:update on clinical characteristics and treatment [PDF]

open access: yes, 2021
Defective thyroid hormone transport due to deficiency in thyroid hormone transporter monocarboxylate transporter 8 (MCT8) results in severe neurodevelopmental delay due to cerebral hypothyroidism and in clinical negative sequelae following a chronic ...
Visser, W. Edward   +5 more
core   +1 more source

Protocol to evaluate the impact of murine MCT1-deficient CD8+ T cells on adipogenesis

open access: yesSTAR Protocols, 2023
Summary: The infiltration of activated T cells, such as CD8+ effector, in metabolic tissues plays a crucial role for the initiation and propagation of obesity-induced inflammation. Given the pivotal role of lactate transporter monocarboxylate transporter
Chiara Macchi   +3 more
doaj   +1 more source

The Effects of Physical Exertion According to the Monocarboxylate Transporter 1 (MCT1) on the Speed of Lactic Acid Elimination in Futsal Players

open access: yesSoshum: Jurnal Sosial dan Humaniora, 2021
To identify the genetic diversity of futsal players in Al Hilla Sports Club for the season (2020-2021) after they were exposed to physical exertion by testing lactic mlss in the speed of recovery and elimination of lactic acid.
Mustafa Jassim Abd Zaed   +2 more
doaj   +1 more source

Monocarboxylate Transporter 4 and Caveolin-1 Expression in Squamous Cell Carcinoma of the Oral Cavity [PDF]

open access: yes, 2012
Poster presented at: 8th International Conference on Head and Neck Cancer in Toronto Canada, July 21-25, 2012. Objective: To determine the significance of caveolin-1 (cav-1) and monocarboxylate transporter 4 (MCT4) in squamous cell carcinoma of the oral
Whitaker-Menezes, PhD, Diana   +7 more
core   +1 more source

Short-chain fatty acids in diseases

open access: yesCell Communication and Signaling, 2023
Short-chain fatty acids (SCFAs) are the main metabolites produced by bacterial fermentation of dietary fibre in the gastrointestinal tract. The absorption of SCFAs is mediated by substrate transporters, such as monocarboxylate transporter 1 and sodium ...
Dan Zhang   +9 more
doaj   +1 more source

IMMUNOHISTOCHEMICAL EXPRESSION OF MONOCARBOXYLATE TRANSPORTER 1&4 IN TANYCYTE–LIKE CELLS OF THE SULCUS MEDIANUS ORGANUM

open access: yesThe Iraqi Journal of Medical Sciences, 2019
Background: Circumventricular organs (CVOs) are specialized structures border the brain ventricles and lack the blood-brain barrier. These CVOs are lined by specialized ependymal cells (ECs) called tanycyte.
Haider Jawad   +2 more
doaj   +1 more source

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