Results 51 to 60 of about 39,988 (211)

MPTP lesioning does not affect serum 25(OH)D levels.

, 2013
After MPTP lesion, serum 25(OH)D levels were measured to determine if MPTP lesion had any effect (Control/Saline Group- 40.40±1.1 ng/ml; Control/MPTP Group- 40.60±1.1 ng/ml; Vitamin D Depletion/Saline Group- 6.60±0.7 ng/ml; Vitamin D Depletion/MPTP Group-
Gary W. Miller (50264), Jeanne E. McKeon (317246), Vin Tangpricha (317252), Kurt D. Pennell (72020), Marian L. Evatt (317255), Jonathan A. Doorn (317250), E. Danielle Dean (317238), Lydia M. Mexas (317241), Natalie L. Cápiro (317243), Mahlon R. DeLong (317248)   +9 more
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Mfn2 Overexpression Attenuates MPTP Neurotoxicity In Vivo

, 2021
Mitochondrial dysfunction represents a critical event in the pathogenesis of Parkinson’s disease (PD). Increasing evidence demonstrates that disturbed mitochondrial dynamics and quality control play an important role in mitochondrial dysfunction in
Fanpeng Zhao, Xiongwei Zhu, Wenzhang Wang, Quillan Austria   +3 more
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Avaliação farmacológica de uma fração rica em proantocianidinas obtida da Croton celtidifolius sobre o sistema nervoso central e em um modelo animal da doença de Parkinson [PDF]

, 2010
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2010No presente estudo investigamos as possíveis propriedades psicofarmacológicas e neuroprotetoras ...
Moreira, Eduardo Luiz Gasnhar
core  

MPTP and MPTP analogs induced cell death in cultured rat hepatocytes involving the formation of pyridinium metabolites

, 1988
MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) which has been shown to produce a Parkinson-like syndrome in humans and monkeys also causes cell death in cultures of rat hepatocytes.
Swanson, Eric, Krishna, Gopal, Krishnan Kutty, R., Sokoloski, Edward, Singh, Yogendra   +4 more
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Dose-dependent response of metformin in enhancing motor performance and dopamine release in C57BL/6 mice afflicted by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

Advances in Medical, Pharmaceutical and Dental Research
Introduction: Clinically, metformin has been used as a cornerstone medicine in blood sugar homeostasis for further than 40 times It was obviously the first line treatment among type 2 diabetes mellitus (T2DM) cases. Recently, fresh places of metformin in
Daha Umar Ishaq, Binta Garba Kurfi, Solomon Ojodemi Oguche   +2 more
doaj   +1 more source

MPTP-induced parkinsonism

Progress in Neurobiology, 1990
This paper will review some of the developments in the investigation of MPTP-induced parkinsonism. It will then focus on how the MPTP syndrome has allowed us to better delineate the nature and causes of the cognitive changes of ...
openaire   +2 more sources

MPTP effect on the nigrostriatal system.

, 2013
Midbrain sections at the level of the 3rd nerve from a control (A), a MPTP short-term (B) and a MPTP long-term treated monkey (C) immunostained for TH. Note the severe reduction of TH immunoreactivity in the SNpc of the lesioned monkeys. Scale bar = 1 cm.
Iñaki Carril-Mundiñano (422922), Rosario Sanchez-Pernaute (312333), Paz Moreno-Murciano (422920), Maria-Rosario Luquin (296415), Nerea Vazquez (422923), Cristina Ordoñez (296412), Maria Hernandez (5655232), Carla Di Caudo (422921), Jose Manuel Garcia-Verdugo (5650549)   +8 more
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Effects of adenosine receptor antagonists in MPTP mouse model of Parkinson’s disease: mitochondrial DNA integrity

, 2017
Introduction: In Parkinson’s disease (PD), compelling data indicate a functional link between adenosine/dopamine receptors and the progression of the neurodegenerative process.
Soha S. Essawy, Horya Erfan Korayem, Mona Kamal Tawfik   +2 more
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Motor Neurons Pathology After Chronic Exposure to MPTP in Mice

, 2020
The neurotoxin 1-methyl,4-phenyl-1,2,3,6-tetrahydropiridine (MPTP) is widely used to produce experimental parkinsonism in rodents and primates. Among different administration protocols, continuous or chronic exposure to small amounts of MPTP is reported ...
Ryskalin, Larisa, Fornai, Francesco, Biagioni, Francesca, Busceti, Carla L, Ferrucci, Michela, D'Este, Loredana, Madonna, Michele, Vivacqua, Giorgio, Yu, Shun   +8 more
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Assessment of Voacanga Africana effect on cognition and motor ability in a mouse model of Parkinson’s disease

National Journal of Physiology, Pharmacy and Pharmacology, 2020
Background: Parkinson disease (PD) is a neurodegenerative affection. At the pre-symptomatic stage, the clinical manifestations are mainly cognitive. Aim and Objective: Our study explores the effects of Voacanga Africana (VOC) on cognitive disorders ...
Houndjo DS, Loubano-Voumbi G, Gnahore Eric, Camara Abdou Aziz, Diop Doudou, Sarr Abdou, Diaw Mor, Sow Abdou K, Seck Aissatou, Toure Maimouna, Coly Mame Saloum, BA Awa, Gaye Magaye, Mbengue Arame, BA Abdoulaye, Sar Fatou Bintou, Samb Abdoulaye   +16 more
doaj   +1 more source