Results 61 to 70 of about 11,376 (201)

Cloning, chromosomal mapping and characterization of the human metal-regulatory transcription factor MTF-1

open access: yesNucleic Acids Research, 1994
Metallothioneins (MTs) are small cysteine-rich proteins that bind heavy metal ions such as zinc, cadmium and copper with high affinity, and have been functionally implicated in heavy metal detoxification and radical scavenging. Transcription of metallothioneins genes is induced by exposure of cells to heavy metals.
E, Brugnera   +6 more
openaire   +3 more sources

The mediating role of shame in the relationship between adolescent hairpulling and co‐occurring anxiety and depressive symptomology

open access: yesJCPP Advances, EarlyView.
This study found that shame is a significant mediator in positive associations between hairpulling severity and depression and anxiety severity within a community sample of adolescents with clinical levels of hair‐pulling severity. It also found high levels of trance‐pulling and post‐pulling rituals.
Talia F. Mayerson   +2 more
wiley   +1 more source

Evaluation of copper nanocatalyst performance in S-methyl thioformate synthesis from carbon monoxide: Structural and mechanistic insights

open access: yesResults in Chemistry
S-methyl thioformate (MTF) holds promise in pharmaceutical applications due to its antimicrobial properties and role in synthesizing therapeutic agents for diseases such as cancer and diabetes.
Fatemeh Fallah Eri Sofla   +2 more
doaj   +1 more source

Transcriptional regulation of the beta-synuclein 5'-promoter metal response element by metal transcription factor-1.

open access: yesPLoS ONE, 2011
The progression of many human neurodegenerative disorders is associated with an accumulation of alpha-synuclein. Alpha-synuclein belongs to the homologous synuclein family, which includes beta-synuclein.
Patrick C McHugh   +2 more
doaj   +1 more source

Interface healing and its correlation with visual recovery and quality of vision following small incision lenticule extraction

open access: yesIndian Journal of Ophthalmology, 2018
Purpose: To study the time course of interface healing and its correlation with visual acuity, modulation transfer function (MTF), and aberrations after myopic small-incision lenticule extraction (SMILE) correction.
Sri Ganesh   +3 more
doaj   +1 more source

Characterization of the mouse gene for the heavy metal-responsive transcription factor MTF-1

open access: yesCell Stress & Chaperones, 2000
MTF-1 is a zinc finger transcription factor that mediates the cellular response to heavy metal stress; its targeted disruption in the mouse leads to liver decay and embryonic lethality at day E14. Recently, we have sequenced the entire MTF-1 gene in the compact genome of the pufferfish Fugu rubripes. Here we have defined the promoter sequences of human
A, Auf der Maur   +6 more
openaire   +3 more sources

Listening in: Orthopaedic Oncology Physicians' Perspectives on Implementation of Audio Recording/Artificial Intelligence Assist in Office Visits

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Introduction With rapid expansion of artificial intelligence (AI) in clinical documentation, responsible implementation of this tool is imperative in preserving the patient‐physician relationship. Orthopaedic oncologists were surveyed to assess their utilization of, and attitudes towards, ambient listening software.
Megan Hsu   +3 more
wiley   +1 more source

MTF-1-Mediated Repression of the Zinc Transporter Zip10 Is Alleviated by Zinc Restriction

open access: yesPLoS ONE, 2011
The regulation of cellular zinc uptake is a key process in the overall mechanism governing mammalian zinc homeostasis and how zinc participates in cellular functions. We analyzed the zinc transporters of the Zip family in both the brain and liver of zinc-deficient animals and found a large, significant increase in Zip10 expression.
Louis A Lichten   +4 more
openaire   +4 more sources

Metal responsive transcription factor 1 (MTF-1) regulates zinc dependent cellular processes at the molecular level [PDF]

open access: yesActa Biochimica Polonica, 2015
Metal responsive transcription factor 1 (MTF-1) is a zinc dependent transcription factor which is involved in the regulation of intracellular signaling pathways. MTF-1 regulates the expression of two streams of genes functioning in metal homeostasis and anti-oxidative response.
Agata, Grzywacz   +5 more
openaire   +2 more sources

Pupil Plane Multiplexing for Vectorial Fourier Ptychography

open access: yesLaser &Photonics Reviews, EarlyView.
This study proposes a cost‐effective, modality‐adaptive multichannel microscopy framework using pupil‐plane multiplexing. A custom pupil aperture at the Fourier plane encodes channel‐specific transfer functions with spectral or polarization filters, and model‐based reconstruction with channel‐dependent priors decodes them.
Hyesuk Chae   +5 more
wiley   +1 more source

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