Mucosal‐associated invariant T cells modulate innate immune cells and inhibit colon cancer growth [PDF]
Scand J ImmunolMucosal-associated invariant T (MAIT) cells are innate-like T cells that can be activated by microbial antigens and cytokines and are abundant in mucosal tissues including the colon.
Beswick, Ellen J. +8 more
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Mucosal-Associated Invariant T Cells: New Insights into Antigen Recognition and Activation
Frontiers in Immunology, 2017 Mucosal-associated invariant T (MAIT) cells, a novel subpopulation of innate-like T cells that express an invariant T cell receptor (TCR)α chain and a diverse TCRβ chain, can recognize a distinct set of small molecules, vitamin B metabolites, derived ...
Xingxing Xiao +3 more
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Role of mucosal-associated invariant T cells in coronavirus disease 2019 vaccine immunogenicity [PDF]
Curr Opin VirolMucosal-associated invariant T (MAIT) cells are an unconventional T cell population that are highly abundant in humans. They possess a semi-invariant T cell receptor (TCR) that recognises microbial metabolites formed during riboflavin biosynthesis ...
Klenerman, Paul +2 more
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Mucosal-associated invariant T cells in infectious diseases of respiratory system: recent advancements and applications [PDF]
J Inflamm (Lond)Mucosal-associated invariant T (MAIT) cells are an atypical subset of T lymphocytes, which have a highly conserved semi-constant αβ chain of T-cell receptor (TCR) and recognize microbe-derived vitamin B metabolites via major histocompatibility complex ...
Xue Lin, Ye Wang, Yanqi He
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Biological functions and therapeutic applications of human mucosal-associated invariant T cells [PDF]
Journal of Biomedical ScienceMucosal-associated invariant T (MAIT) cells are a unique subset of innate-like T lymphocytes that bridge innate and adaptive immunity. Characterized by their semi-invariant T cell receptor (TCR) and abundant localization in mucosal tissues, MAIT cells ...
Ying Fang +7 more
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Mucosal-associated invariant T cells in hematological malignancies: Current knowledge, pending questions [PDF]
Frontiers in Immunology, 2023 Non-classical HLA restricted T cell subsets such as γδ T and NK-T cells are showing promises for immune-based therapy of hematological malignancies. Mucosal-Associated Invariant T cells (MAIT) belong to this family of innate-like T cell subsets and are ...
Emmanuel Treiner +2 more
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Mucosal-Associated Invariant T (MAIT) Cells Are Impaired in Th17 Associated Primary and Secondary Immunodeficiencies. [PDF]
, 2016 The recently described Mucosal Associated Invariant T (MAIT) cells mediate specific recognition of bacterial and fungal vitamin B2 metabolites. As innate T cells, they possess broad effector responses, including IFN- including Iproduction, that are ...
Gabriela Barcenas-Morales +26 more
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Regulation and heterogeneity of human mucosal-associated invariant T (MAIT) cells in blood and liver
, 2021 Mucosal-associated invariant T (MAIT) cells are an abundant population of innate-like, effector memory T cells, that secrete proinflammatory cytokines and exhibit direct cytotoxic activity.
Garner, Lucy catherine
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Mucosal-Associated Invariant T Cells in Regenerative Medicine
Frontiers in Immunology, 2017 Although antibiotics to inhibit bacterial growth and small compounds to interfere with the productive life cycle of human immunodeficiency virus (HIV) have successfully been used to control HIV infection, the recent emergence of the drug-resistant ...
Hiroshi Wakao +3 more
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Mucosal-Associated Invariant T Cells in T-Cell Non-Hodgkin Lymphomas: A Case Series
, 2022 SIMPLE SUMMARY: Mucosal-associated invariant T (MAIT) cells are a subgroup of T lymphocytes whose role has recently been investigated in several types of diseases, including cancer. However, little is known about these cells in lymphomas.
Persico, Marcello +23 more
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