Results 101 to 110 of about 487,050 (179)

[Multispecific monoclonal antibodies].

Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1992
Immunization of BALB/c mice with Rickettsia prowazekii antigens, Bordetella pertussis toxin and Legionella pneumophila cytolysin induces the synthesis of IgM autoantibodies of different specificity. Among monoclonal antibodies, multispecific antibodies with a wide reactivity spectrum have been found to make up high percentage (30-80%).
E I, Drobyshevskaia, S V, Spitsyn, Iu A, Nedialkov, V G, Nesterenko   +3 more
openaire   +1 more source

Intramolecular trimerization, a novel strategy for making multispecific antibodies with controlled orientation of the antigen binding domains

Here, we describe a new strategy that allows the rapid and efficient engineering of mono and multispecific trivalent antibodies. By fusing single-domain antibodies from camelid heavy-chain-only immunoglobulins (VHHs) to the N-terminus of a human collagen
Cuesta, Angel M., Blanco-Toribio, Ana, Merino, Nekane, Oliva Miguel, Baldomero, Harwood, Seandean Lykke, Mølgaard, Kasper, Blanco, Francisco, Navarro, Rocio, Villate, Maider, Compte, Marta, Bonet Martínez, Jaume, 1982-, Muñoz-Briones, Clara, Sørensen, Karen Marie Juul, Sanz, Laura, Alvarez-Cienfuegos, Ana, Nuñez-Prado, Natalia, Alvarez-Vallina, Luis   +16 more
core  

Anti-neurofascin antibodies [PDF]

, 2012
Neurofascin (NF) is a cell-adhesion molecule that is found at the nodes of Ranvier. The 186 kDa isoform of neurofascin (NF186) is expressed on the axon in the exposed node, and the 155 kDa isoform (NF155) is expressed on myelinating glia at the ...
Ng, King Man
core  

Patient-Specific Vascularized Tumor Model: Blocking TAM Recruitment with Multispecific Antibodies Targeting CCR2 and CSF-1R

, 2023
Nguyen HT, Gurvich N, Gillrie MR, Offeddu G, Humayun M, Kan EL, Wan Z, Coughlin MF, Zhang C, Vu V, Ling Lee SW, Tan S, Barbie D, Hsu J, Kamm RD.   +14 more
europepmc   +1 more source

Rethinking Monospecific Antibody Therapy in Chronic Rhinosinusitis with Nasal Polyps: Dual- and Multispecific Antibodies. [PDF]

Clin Rev Allergy Immunol
Dai Y, Guo T, Shi M, Wang D, Wang M.
europepmc   +1 more source

Evolution of bispecific and multispecific antibodies in cancer therapy. [PDF]

Lancet Reg Health Eur
Fontana E, Grochot R, Kotecki N, Doger B, Nannini S, de Miguel M.   +5 more
europepmc   +1 more source

The use of CrossMAb technology for the generation of bi- and multispecific antibodies. [PDF]

MAbs, 2016
Klein C, Schaefer W, Regula JT.
europepmc   +1 more source

End-To-End Automated Intact Protein Mass Spectrometry for High-Throughput Screening and Characterization of Bispecific and Multispecific Antibodies. [PDF]

Anal Chem
Niu B, Lee B, Chen W, Alberto C, Betancourt Moreira K, Compton P, Homan K, Pinckney J, Zhu Y, Vendel M, Wetterhorn K, Walrond S, Santha E, Horowitz A, Zaubi N, Johnson J.   +15 more
europepmc   +1 more source

Nomenclature of therapies in inflammatory bowel disease: A journey through time and terminology. [PDF]

Inflamm Bowel Dis
Colwill M, Patel K, Sebastian S, Din S, Honap S.   +4 more
europepmc   +1 more source