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Antibody-Antibiotic Conjugates: Mechanisms, Clinical Progress, and Next-Generation Strategies Against Multidrug-Resistant Bacterial Infections. [PDF]
MicrobiologyopenAskari P +3 more
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Analytical similarity as the primary determinant of monoclonal antibody development: toward evidence-efficient regulatory frameworks. [PDF]
Front Drug DelivNiazi SK.
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Potential of alarmin-targeted bispecific and combination therapies in airway disease. [PDF]
Front AllergyKomori HK, Ortega H.
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Exploring the frontiers: a panoramic analysis of global multi-specific antibody clinical trials. [PDF]
Int J SurgGao S, Zhang Y, Han J, Zhao J.
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Bispecific and multispecific T-cell engagers: advancing the future of immunotherapy. [PDF]
Antib TherKang X, Zhao Y, Ling H, Huang X.
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Multispecific monoclonal antibodies
Trends in Immunology, 1986Monoclonal antibodies are frequently shown to participate in unexpected cross reactions involving two apparently dissimilar antigens. This can be attributed either to partial epitope identity or to irrelevant interactions involving additional binding capacity of the antibody.
David Isenberg
exaly +5 more sources
Expression of Multispecific Antibodies
Methods in Molecular BiologyBi- and multispecific antibody formats allow the development of new therapeutic strategies to address previously unmet medical needs. However, due to the increased complexity (e.g., the interface design and the presence of multiple binders), such molecules are generally more challenging to express and purify compared to standard monoclonal antibodies ...
Megane, Peltret +5 more
exaly +3 more sources