Results 111 to 120 of about 2,301 (144)
Potential of alarmin-targeted bispecific and combination therapies in airway disease. [PDF]
Front AllergyKomori HK, Ortega H.
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Analytical similarity as the primary determinant of monoclonal antibody development: toward evidence-efficient regulatory frameworks. [PDF]
Front Drug DelivNiazi SK.
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Exploring the frontiers: a panoramic analysis of global multi-specific antibody clinical trials. [PDF]
Int J SurgGao S, Zhang Y, Han J, Zhao J.
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Advantages of MabSelect VH3, a novel VH3-specific Protein A resin, over its two conventional counterparts in purifying a VHH-based trispecific antibody. [PDF]
J Biol MethodsFang D, Qi W, Li Y.
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Multispecific monoclonal antibodies
Trends in Immunology, 1986Monoclonal antibodies are frequently shown to participate in unexpected cross reactions involving two apparently dissimilar antigens. This can be attributed either to partial epitope identity or to irrelevant interactions involving additional binding capacity of the antibody.
David A Isenberg
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Antibody multispecificity: A necessary evil?
Molecular Immunology, 2022Antibodies represent key effectors of the adaptive immune system. The specificity of antibodies is an established hallmark of the immune response. However, a certain proportion of antibodies exhibit limited promiscuity or multireactivity. Germline antibodies display plasticity which imparts multispecificity to enhance the antibody repertoire ...
Deepika, Jaiswal +3 more
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