VERITAS: Harnessing the power of nomenclature in biologic discovery
mAbs, 2023 We are entering an era in which therapeutic proteins are assembled using building block-like strategies, with no standardized schema to discuss these formats. Existing nomenclatures, like AbML, sacrifice human readability for precision.
Riti Biswas +6 more
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Development of antibodies for life-detection experiment in extreme environments; implications for astrobiology [PDF]
, 2010 The Life Marker Chip (LMC) instrument is an antibody assay-based system which will attempt to detect molecular signatures of Life in the Martian subsurface as part of the payload on board the European Space Agency (ESA) ExoMars mission rover, currently
Derveni, Maria Elisavet
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Engineering multi-specific antibodies against HIV-1
Retrovirology, 2018 As increasing numbers of broadly neutralizing monoclonal antibodies (mAbs) against HIV-1 enter clinical trials, it is becoming evident that combinations of mAbs are necessary to block infection by the diverse array of globally circulating HIV-1 strains ...
Neal N. Padte +3 more
doaj +1 more source
Generation of a symmetrical trispecific NK cell engager based on a two-in-one antibody
Frontiers in Immunology, 2023 To construct a trispecific IgG-like antibody at least three different binding moieties need to be combined, which results in a complex architecture and challenging production of these molecules.
Julia Harwardt +9 more
doaj +1 more source
Human monoclonal antibodies and monoclonal antibody multispecificity [PDF]
British Journal of Cancer, 1987 The majority of human anti-tumour monoclonal antibodies (Mabs) isolated to date have been disappointing. Firstly, they react or cross react with intracellular cytoskeletal proteins or nuclear antigens and therefore are of limited value as blood borne agents.
A M, Campbell, P, Whitford, R E, Leake
openaire +2 more sources
Acknowledgment to Reviewers of Antibodies in 2020
, 2021 Peer review is the driving force of journal development, and reviewers are gatekeepers who ensure that Antibodies maintains its standards for the high quality of its published papers [...
Antibodies Editorial Office
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Acknowledgement to Reviewers of Antibodies in 2018
, 2019 Peer review is an essential part of the publication process, ensuring that Antibodies maintains high quality standards for its published papers.
Antibodies Editorial Office Antibodies Editorial Office
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Generation of Multispecific Antibodies with Immune Cell Modulating Functions [PDF]
, 2023 Within the field of biologics, monoclonal antibodies have ruled the market with blockbuster and top selling drugs over the last decades. With the advancements in technological discoveries, lightspeed progress has been achieved to discover novel ...
Carrara, Stefania C.
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Efficient and inexpensive transient expression of multispecific multivalent antibodies in Expi293 cells [PDF]
, 2017 Background: Immunotherapy is a very fast expanding field within drug discovery and, hence, rapid and inexpensive expression of antibodies would be extremely valuable. Antibodies are, however, difficult to express.
Hultqvist, Greta +14 more
core +1 more source
CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems
The FEBS Journal, EarlyView.Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén +11 more
wiley +1 more source