Results 171 to 180 of about 71,509 (231)

Effect of anticholinergic eye drops on intraorbital, periorbital and brain pulsation power

open access: yesActa Ophthalmologica, Volume 103, Issue 7, Page e511-e523, November 2025.
Abstract Purpose The study aims to investigate the effect of pharmacologically reducing parasympathetic activity on ocular and cerebral pulsations, inspired by recent discoveries of a glymphatic‐like system in the eye driven by physiological pulsations.
Seyed Mohsen Ebrahimi   +8 more
wiley   +1 more source

Anticholinergic Action of Disopyramide in Intestinal Smooth Muscle of the Guinea Pig: Inhibition of Muscarinic Receptors (M1 and M2)

open access: diamond, 1990
Yukisato Ishida   +5 more
openalex   +1 more source

Fentanyl Disrupts Vagal Control of Airway Tone to Induce Transient Obstruction

open access: yesActa Physiologica, Volume 241, Issue 11, November 2025.
ABSTRACT Aim Opioid‐induced respiratory depression (OIRD) is the primary cause of death in opioid overdose, resulting from both suppressed respiratory rhythm and increased airway and thoracic rigidity that compromise ventilation and resuscitation. While the effect(s) of opioids on central rhythm‐generating circuits are well documented, the mechanisms ...
Riley R. Parks   +3 more
wiley   +1 more source

Structure–activity relationship of the allosteric effects of ivermectin at human P2X4 and GABAA receptors

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 21, Page 5286-5302, November 2025.
Abstract Background and purpose Positive allosteric modulation of the P2X4 receptor is a potential route to providing cardiovascular benefit through enhancing flow‐dependent arterial vasodilation and providing cardioprotection. However, ligands that selectively enhance P2X4 activity are absent.
Jessica L. Meades   +4 more
wiley   +1 more source

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