Results 31 to 40 of about 396,076 (261)
Induction of Suppressor Cells and Increased Tumor Growth following Chronic Psychosocial Stress in Male Mice. [PDF]
PLoS ONE, 2016 To study the impact of psychosocial stress on the immune system, male mice were subjected to chronic subordinate colony housing (CSC), a preclinically validated mouse model for chronic psychosocial stress.
Dominic Schmidt +4 more
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Myeloid-derived suppressor cells in gliomas
Contemporary Oncology, 2016 Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of early myeloid progenitors and precursors at different stages of differentiation into granulocytes, macrophages, and dendritic cells.
Anna Gieryng, Bozena Kaminska
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Myeloid Cell Turnover and Clearance [PDF]
Microbiology Spectrum, 2016 ABSTRACTGiven the dual and intrinsically contradictory roles of myeloid cells in both protective and yet also damaging effects of inflammatory and immunological processes, we suggest that it is important to consider the mechanisms and circumstances by which these cells are removed, either in the normal unchallenged state or during inflammation or ...
William J, Janssen +3 more
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Characteristics of Tip-DCs and MDSCs and their potential role in leishmaniasis
Frontiers in Microbiology, 2012 Since the first description of dendritic cells (DCs) by Ralph Marvin Steinman and Zanvil Alexander Cohn in 1973, the myeloid lineage of leukocytes was investigated intensively.
Maximilian eSchmid +2 more
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Shp1 function in myeloid cells [PDF]
Journal of Leukocyte Biology, 2017 Abstract The motheaten mouse was first described in 1975 as a model of systemic inflammation and autoimmunity, as a result of immune system dysregulation. The phenotype was later ascribed to mutations in the cytoplasmic tyrosine phosphatase Shp1.
Clare L, Abram, Clifford A, Lowell
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Breast Cancer Research, 2023 Background Breast cancer presents as one of the top health threats to women around the world. Myeloid cells are the most abundant cells and the major immune coordinator in breast cancer tumor microenvironment (TME), target therapies that harness the anti-
Chenxuan Yang +9 more
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Targeting Metabolic Pathways of Myeloid Cells Improves Cancer Immunotherapy
Frontiers in Cell and Developmental Biology, 2021 Tumor-infiltrating myeloid cells are a prominent pro-tumorigenic immune cell population that limit host anti-tumor immunity and present a significant obstacle for many cancer immunotherapies.
Jianying Li +5 more
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OncoImmunology, 2017 The colorectal tumor microenvironment contains a diverse population of myeloid cells that are recruited and converted to immunosuppressive cells, thus facilitating tumor escape from immunoediting.
Xiaowei Chen +11 more
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Myeloid-Derived Suppressor Cells in Some Oncohematological Diseases
Клиническая онкогематология, 2017 Myeloid-derived suppressor cells are immature myeloid cells with immunosuppressive properties. The review presents characteristics of myeloid-derived suppressor cells.
Aleksandr Vasil’evich Ponomarev
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Transposable elements in hematopoietic stem cells upon aging and myeloid malignancies
Mobile DNATransposable elements (TEs) constitute nearly half of the human genome and profoundly influence hematopoietic stem cell (HSC) biology. In this review, we synthesize current evidence demonstrating that TEs exert dual and context-dependent roles in HSCs ...
Emilie Elvira-Matelot, Françoise Porteu
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