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Myeloid Cells in Infantile Hemangioma [PDF]
The American Journal of Pathology, 2006 Little is known about the pathogenesis of infantile hemangiomas despite the fact that they are relatively common tumors. These benign neoplasms occur in as many as 1 in 10 births, and although rarely life threatening, hemangiomas can pose serious concerns to the cosmetic and psychosocial development of the afflicted child.
Matthew R, Ritter +3 more
openaire +2 more sources
Turn Back the TIMe: Targeting Tumor Infiltrating Myeloid Cells to Revert Cancer Progression
Frontiers in Immunology, 2018 Tumor cells frequently produce soluble factors that favor myelopoiesis and recruitment of myeloid cells to the tumor microenvironment (TME). Consequently, the TME of many cancer types is characterized by high infiltration of monocytes, macrophages ...
Robin Maximilian Awad +4 more
doaj +1 more source
Induction of Suppressor Cells and Increased Tumor Growth following Chronic Psychosocial Stress in Male Mice. [PDF]
PLoS ONE, 2016 To study the impact of psychosocial stress on the immune system, male mice were subjected to chronic subordinate colony housing (CSC), a preclinically validated mouse model for chronic psychosocial stress.
Dominic Schmidt +4 more
doaj +1 more source
Eradication of chronic myeloid leukemia stem cells: a novel mathematical model predicts no therapeutic benefit of adding G-CSF to imatinib [PDF]
, 2009 Imatinib mesylate induces complete cytogenetic responses in patients with chronic myeloid leukemia (CML), yet many patients have detectable BCR-ABL transcripts in peripheral blood even after prolonged therapy.
Holyoake, T. +14 more
core +2 more sources
Immunorecognition of leukemic stem cells by NK cells : the role of HDAC inhibitors in NKG2D ligand-mediated anti-tumor responses in acute myeloid leukemia [PDF]
, 2008 The diagnosis of acute myeloid leukemia (AML) is associated to a poor long-term outcome due to frequent relapse despite intensive chemotherapy, radiation and hematopoietic stem cell transplantation (HSCT) as well as continuous advances in treatment ...
Langenkamp, Ulrich
core +1 more source
Breast Cancer Research, 2023 Background Breast cancer presents as one of the top health threats to women around the world. Myeloid cells are the most abundant cells and the major immune coordinator in breast cancer tumor microenvironment (TME), target therapies that harness the anti-
Chenxuan Yang +9 more
doaj +1 more source
Shp1 function in myeloid cells [PDF]
Journal of Leukocyte Biology, 2017 Abstract The motheaten mouse was first described in 1975 as a model of systemic inflammation and autoimmunity, as a result of immune system dysregulation. The phenotype was later ascribed to mutations in the cytoplasmic tyrosine phosphatase Shp1.
Clare L, Abram, Clifford A, Lowell
openaire +2 more sources
OncoImmunology, 2017 The colorectal tumor microenvironment contains a diverse population of myeloid cells that are recruited and converted to immunosuppressive cells, thus facilitating tumor escape from immunoediting.
Xiaowei Chen +11 more
doaj +1 more source
Myeloid-Derived Suppressor Cells in Some Oncohematological Diseases
Клиническая онкогематология, 2017 Myeloid-derived suppressor cells are immature myeloid cells with immunosuppressive properties. The review presents characteristics of myeloid-derived suppressor cells.
Aleksandr Vasil’evich Ponomarev
doaj +1 more source
Targeting Metabolic Pathways of Myeloid Cells Improves Cancer Immunotherapy
Frontiers in Cell and Developmental Biology, 2021 Tumor-infiltrating myeloid cells are a prominent pro-tumorigenic immune cell population that limit host anti-tumor immunity and present a significant obstacle for many cancer immunotherapies.
Jianying Li +5 more
doaj +1 more source