Results 91 to 100 of about 3,551 (133)

ALKBH3‐Mediated M1A Demethylation of METTL3 Endows Pathological Fibrosis:Interplay Between M1A and M6A RNA Methylation

Advanced Science
Epigenetic modifications serve as crucial molecular switches for pathological fibrosis; howbeit the role of m1A in this condition remains enigmatic. Herein, it is found that ALKBH3 exerts a pro‐fibrotic effect in pathological skin fibrosis by reshaping ...
Liying Tu, Shuchen Gu, Ruoqing Xu, En Yang, Xin Huang, Hsin Liang, Shenying Luo, Haizhou Li, Yixuan Zhao, Tao Zan   +9 more
doaj   +1 more source

The regulatory role of N1-methyladenosine in tRNA in the development of urothelial carcinoma of the bladder

, 2023
Urothelial carcinoma of the bladder (BLCA) is a disease of high occurrence globally. A high recurrence frequency often necessitates lifelong control schemes of invasive examinations and harsh treatment, reducing the life quality of patients. Several RNA-modifying proteins have been associated with BLCA, and a link between transfer RNA (tRNA ...
openaire   +2 more sources

Writers, readers, and erasers RNA modifications and drug resistance in cancer

Molecular Cancer
Drug resistance in cancer cells significantly diminishes treatment efficacy, leading to recurrence and metastasis. A critical factor contributing to this resistance is the epigenetic alteration of gene expression via RNA modifications, such as N6 ...
Di Chen, Xinyu Gu, Yeltai Nurzat, Lixia Xu, Xueyuan Li, Lixin Wu, Henan Jiao, Peng Gao, Xuqiang Zhu, Dongming Yan, Shaohua Li, Chen Xue   +11 more
doaj   +1 more source

A Fluorescent Aptasensor for Sensitive and Selective Determination of Epigenetic Cancer Biomarker N¹-Methyladenosine in Urine Samples. [PDF]

Chemistry
Bağda E, Bağda E, Liu J.
europepmc   +1 more source

YTHDF2 Recognition of N¹-Methyladenosine (m¹A)-Modified RNA Is Associated with Transcript Destabilization. [PDF]

ACS Chem Biol, 2020
Seo KW, Kleiner RE.
europepmc   +1 more source

The landscape of N¹-methyladenosine (m¹A) modification in mRNA of the decidua in severe preeclampsia. [PDF]

Biomol Biomed
Tong J, Li H, Zhang L, Zhang C.
europepmc   +1 more source

Identification of YTH Domain-Containing Proteins as the Readers for N1-Methyladenosine in RNA. [PDF]

Anal Chem, 2018
Dai X, Wang T, Gonzalez G, Wang Y.
europepmc   +1 more source

The Molecular Basis of Human ALKBH3 Mediated RNA N¹ -methyladenosine (m¹ A) Demethylation. [PDF]

Angew Chem Int Ed Engl
Zhang L, Duan HC, Paduch M, Hu J, Zhang C, Mu Y, Lin H, He C, Kossiakoff AA, Jia G, Zhang L.   +10 more
europepmc   +1 more source

RAMPred: identifying the N(1)-methyladenosine sites in eukaryotic transcriptomes. [PDF]

Sci Rep, 2016
Chen W, Feng P, Tang H, Ding H, Lin H.
europepmc   +1 more source