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Studies on the Specificity of Narcotic Antagonists [PDF]

open access: bronzeAnesthesiology, 1965
Experiments with five narcotics, (morphine 0.3 mg./kg., oxymorphone 20 μg./kg., levorphan 50 μg./kg., meperidine 1.5 μg./kg. and fentanyl 1.5 μ./kg.) and three narcotic antagonists (nalorphine 150 μg./kg., naloxone 5 μg./kg., and levallorphan 20 μg./kg ...
Francis F. Foldes   +4 more
semanticscholar   +5 more sources

Human pharmacology of narcotic antagonists. [PDF]

open access: greenBritish Journal of Clinical Pharmacology, 1979
1 Human studies at the Addiction Research Center enable narcotic antagonists to be classified into three subgroups: (1) nalorphine-like agents; (2) pure antagonists; and (3) morphine-like agents.
DR Jasinski
semanticscholar   +5 more sources

Cannabinoid Hyperemesis Syndrome - A Case Report of an uncommon condition [PDF]

open access: yesEuropean Psychiatry, 2023
Introduction The increasing prevalence of cannabis use in the world requires awareness of cannabis-related disorders such as cannabinoid hyperemesis syndrome (CHS).
B. Peixoto   +4 more
doaj   +2 more sources

The narcotic antagonist naltrexone has a biphasic effect on the nicotinic acetylcholine receptor [PDF]

open access: bronze, 1985
It is known that narcotic antagonists interact with many cholinergic pathways but less in known about specific mechanisms. Using neonatal rat myoballs to study single channel behaviour of the acetylcholinegated nicotinic receptor, it was found that ...
Albuquerque, E.X., Madsen, B.W.
core   +2 more sources

Studies on the assesment of analgesic actions of narcotic antagonists with special reference to nociception induced by retrograde injection of bradykinin into the carotid artery of rat.

open access: bronzeNihon yakurigaku zasshi. Folia pharmacologica Japonica, 1971
The assesment of analgesic action of narcotic antagonists by their ability to block the response of rat to retrograde intra-arterial injection of bradykinin was first reported by Blane.
Takeshi Abe   +2 more
openalex   +3 more sources

Theoretic Significance of pH Dependence of Narcotics and Narcotic Antagonists in Clinical Anesthesia

open access: bronzeAnesthesia and Analgesia, 1976
Determination of the effect of pH and temperature on pKa partition, and drug distribution coefficients in a series of common narcotics and their antagonists has shown that within the range of blood pH (7.1 to 7.7) encountered in the practice of ...
Donald W. Benson   +2 more
openalex   +2 more sources

Use of narcotic antagonists in anaesthesia. [PDF]

open access: greenBritish Journal of Clinical Pharmacology, 1979
1 The introduction of morphine antagonists into anaesthesiology has aroused great scientific interest, increased our knowledge of analgesia, and opened new frontiers for therapeutics. 2 The advantages and disadvantages of these compounds are described and assessed.
Castro João Jácome de
openalex   +4 more sources

THE EFFECT OF NARCOTIC AND NARCOTIC-ANTAGONIST DRUGS IN THE NEWBORN RABBIT

open access: bronzeBritish Journal of Anaesthesia, 1976
The newborn rabbit responds to acute anoxia, as a result of breathing nitrogen, with successive periods of dyspnoea, primary apnoea, gasping and terminal apnoea. Pethidine caused an increase in the period of primary apnoea and a decrease in the duration and rate of gasping.
G.W. STEPHEN   +2 more
openalex   +4 more sources

Book Review: Narcotics and Narcotic Antagonists [PDF]

open access: bronzeProceedings of the Royal Society of Medicine, 1965
Laurence Després
openalex   +3 more sources

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