Results 71 to 80 of about 4,454 (194)
B4GALNT2 and xenotransplantation: A newly appreciated xenogeneic antigen [PDF]
, 2018 Analysis of non-Gal antibody induced after pig-to-baboon cardiac xenotransplantation identified the glycan produced by porcine beta-1,4-N-acetyl-galactosaminyltransferase 2 (B4GALNT2) as an immunogenic xenotransplantation antigen.
Ahmad-Villiers, S +3 more
core +1 more source
Organ Transplantation: Current Status, Challenges, and Future Prospects
MedComm, Volume 7, Issue 1, January 2026.Organ transplantation success relies on precise modulation of the alloimmune response across distinct temporal phases of rejection. Hyperacute rejection results from preformed antibodies activating complement and causing thrombosis, while acute rejection involves T cell‐ and antibody‐mediated mechanisms that drive endothelial activation and ...
Xinqiang Li, Ruidong Ding, Jinzhen Cai
wiley +1 more source
Replication of H9 influenza viruses in the human ex vivo respiratory tract, and the influence of neuraminidase on virus release [PDF]
, 2017 H9N2 viruses are the most widespread influenza viruses in poultry in Asia. We evaluated the infection and tropism of human and avian H9 influenza virus in the human respiratory tract using ex vivo respiratory organ culture.
Chan, LY +9 more
core +1 more source
Molecular Nutrition &Food Research, Volume 70, Issue 2, 29 January 2026.Good nutrition in pregnancy and early life plays a key role in shaping the offspring gut microbiota, which supports healthy growth, immune maturation, and neurodevelopment. Poor maternal and early‐life diets can disrupt this process, increasing the risk of obesity, undernutrition, and disease later in life.
Fanette Fontaine +5 more
wiley +1 more source
Chemo-enzymatic synthesis of Neu5Gc-containing sialylated lactulose
Tropical Journal of Pharmaceutical Research, 2017 Purpose: To synthesize novel sialylated lactuloses, namely, Neu5Gc-α2,3-lactulose and Neu5Gc-α2,6-lactulose.Methods: ManNGc was chemically synthesized from commercially available N-acetylmannosaime (ManNAc), which was used as the donor substrate to synthesize α-(2→3) linkage and α-(2→6) linkage sialyllactulose from lactulose via sialyltransferases ...
Zeng, Jie +6 more
openaire +3 more sources
Reply to Mackenzie: A comparison of Neu5Gc and α-gal xenoantigens [PDF]
Proceedings of the National Academy of Sciences, 2015 We appreciate the thoughtful comments of K. J. Mackenzie (1) regarding our findings, concerning how a red meat-derived glycan can promote inflammation and cancer progression (2). At first glance, there do indeed appear to be very close similarities between the nonhuman sialic acid N-glycolylneuraminic acid (Neu5Gc) antigen we are describing and the ...
Oliver M T, Pearce +4 more
openaire +2 more sources
Research, 2022 Evaluating tumor development is of great importance for clinic treatment and therapy. It has been known that the amounts of sialic acids on tumor cell membrane surface are closely associated with the degree of cancerization of the cell. So, in this work,
Liangfen Cheng +7 more
doaj +1 more source
Identification of TPRA1 as a Novel Receptor and Predictive Biomarker for Oncolytic Virus M1
Advanced Science, Volume 12, Issue 48, December 29, 2025.This study identifies transmembrane protein adipocyte‐associated 1 (TPRA1) as a novel receptor for oncolytic virus M1 (OVM). TPRA1's ectodomain binds OVM particles, while its intracellular domain facilitates virus internalization, promoting efficient viral entry.
Linyi Hu +20 more
wiley +1 more source
Frontiers in Immunology, 2019 The description of “serum sickness” more than a century ago in humans transfused with animal sera eventually led to identification of a class of human antibodies directed against glycans terminating in the common mammalian sialic acid N ...
Chirag Dhar +5 more
doaj +1 more source
Biosynthesis and expression of zona pellucida glycoproteins in mammals [PDF]
, 2001 The zona pellucida (ZP) is an extracellular matrix surrounding the oocyte and the early embryo that exerts several important functions during fertilization and early embryonic development.
Kölle, S. +2 more
core +1 more source