Results 101 to 110 of about 151,448 (273)

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai   +2 more
wiley   +1 more source

Potential of isothiocyanate sulforaphane from broccoli to combat obesity and type 2 diabetes: involvement of NRF2 regulatory pathway [PDF]

open access: yesThe Ukrainian Biochemical Journal
Biologically active food components are now considered to be remedies for the prevention and treatment of metabolic disorders of different etiology. The aim of this review was to analyze the current data on the application of isothiocyanate sulforaphane,
M. V. Ivanochko   +2 more
doaj   +1 more source

Tissue oxygenation dynamics during transition from seizure to spreading depolarization in rat brain

open access: yesEpilepsia, EarlyView.
Abstract Objective Spreading depolarization (SD) is a phenomenon underlying various neurological conditions, including epilepsy. Researchers have suspected that local tissue oxygenation breakdown induces spontaneous SD. In this study, we investigated the relationship between spontaneous epileptic seizures and SD, with a focus on the role of local ...
Jiayang Liu, Bruce J. Gluckman
wiley   +1 more source

Spectroscopy of the soliton lattice formation in quasi-one-dimensional fermionic superfluids with population imbalance

open access: yes, 2011
Motivated by recent experiments in low-dimensional trapped fermionic superfluids, we study a quasi-one-dimensional (quasi-1D) superfluid with a population imbalance between two hyperfine states using an exact mean-field solution for the order parameter ...
Dzero, Maxim   +2 more
core   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

open access: yesIbrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Instantons and Non-Perturbative Dynamics of N=2 Supersymmetric Abelian Gauge Theories in Two Dimensions

open access: yes, 1998
We study N=2 supersymmetric Abelian gauge model with the Fayet-Iliopoulos term and an arbitrary number of chiral matter multiplets in two dimensions. By analyzing the instanton contribution we compute the non-perturbative corrections to the mass spectrum
't Hooft   +44 more
core   +1 more source

Intestinal NF-E2-related factor-2 expression and antioxidant activity changes in rats undergoing orthotopic liver autotransplantation

open access: yesOncology Letters, 2013
Liver transplantation is known to trigger intestinal injuries. Oxidative damage that is induced by reactive oxygen species (ROS) plays a crucial role in ischemia-reperfusion injuries. NF-E2-related factor-2 (Nrf2) and its modulated antioxidant enzymes form the critical endogenous antioxidant system to scavenge ROS.
GE, MIAN   +6 more
openaire   +3 more sources

Substrate Characterization of Mycobacterial Kinase PknG Revealing PknG‐KARS‐MAPK Phosphorylation Signaling Axis in Host

open access: yesiMetaMed, EarlyView.
This study employed multi‐omics approaches to investigate the regulatory mechanism of Mycobacterium PknG on host cell processes. We found that host lysine‐tRNA ligase (KARS) is a potential substrate of PknG; and PknG can regulate the immune response by catalyzing the phosphorylation of KARS at T592 and T595 sites, affecting the phosphorylation level in
Nana Tian   +13 more
wiley   +1 more source

Phases of N=1 USp(2N_c) Gauge Theories with Flavors

open access: yes, 2003
We studied the phase structures of N=1 supersymmetric USp(2N_c) gauge theory with N_f flavors in the fundamental representation as we deformed the N=2 supersymmetric QCD by adding the superpotential for adjoint chiral scalar field. We determined the most
A. Giveon   +28 more
core   +1 more source

Isoacteoside induces heme oxygenase-I via activation of ERK and NF-E2 related factor 2 transcription factor

open access: yesJournal of Medicine and Life Science, 2009
Isoacteoside was isolated from Clerdendron trichotomum Thunb that belongs to Verbenaceae family. We found that isoacteoside the heme oxygenase-1 (HO-1) expression in a time dependent manner, Furthermore, isoacteoside increased the expression of NF-E2 regulated factor 2 (Nrf2), which is a transcription factor of HO-1, in a time dependent manner ...
Dong Ok Ko, Kyoung Ah Kang, Jin Won Hyun
openaire   +1 more source

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