Results 21 to 30 of about 628,729 (310)
Memory NK cell features exploitable in anticancer immunotherapy [PDF]
, 2019 Besides their innate ability to rapidly produce effector cytokines and kill virus-infected or transformed cells, natural killer (NK) cells display a strong capability to adapt to environmental modifications and to differentiate into long-lived ...
Battella, Simone +5 more
core +2 more sources
Nanomaterial‐Boosted Tumor Immunotherapy Through Natural Killer Cells
Advanced NanoBiomed Research, 2022 Natural killer (NK)‐cell immunotherapy as an alternative to T‐cell immunotherapy has been widely used in clinical cell immunotherapy of various tumors.
Mengsi Zhan +3 more
doaj +1 more source
Expression of CD226 is associated to but not required for NK cell education [PDF]
, 2017 DNAX accessory molecule-1 (DNAM-1, also known as CD226) is an activating receptor expressed on subsets of natural killer (NK) and T cells, interacts with its ligands CD155 or CD112, and has co-varied expression with inhibitory receptors. Since inhibitory
Bernhardt, Günter +9 more
core +2 more sources
Leukemia, 2021 AbstractNatural killer/T-cell lymphoma (NKTL) is a sub-type of Epstein–Barr virus (EBV)-related non-Hodgkin lymphomas common in Asia and Latin America but rare elsewhere. Its pathogenesis is complex and incompletely understood. Lymphoma cells are transformed from NK- or T-cells, sometimes both.
Hua Wang +3 more
openaire +2 more sources
Nature Reviews Immunology, 2017 My interest in uterine natural killer (NK) cells began in the early 1990s, when I and others described the striking accumulation of NK cells in the uterine mucosa during the establishment of the placenta. Whilst working as a reproductive pathologist, I had become intrigued by pre-eclampsia, a mysterious syndrome that only occurs in pregnant women.
openaire +2 more sources
Uterine NK cells are critical in shaping DC immunogenic functions compatible with pregnancy progression. [PDF]
, 2012 Dendritic cell (DC) and natural killer (NK) cell interactions are important for the regulation of innate and adaptive immunity, but their relevance during early pregnancy remains elusive.
Burghard F. Klapp +11 more
core +11 more sources
A novel membrane-bound interleukin-2 promotes NK-92 cell persistence and anti-tumor activity
OncoImmunology, 2022 A major challenge in natural killer (NK) cell immunotherapy is the limited persistence of NK cells in vivo. However, the proliferation of NK cells is dependent on cytokines such as interleukin-2 (IL-2).
Qi Xiong +14 more
doaj +1 more source
Transgenic expression of the Ly49A natural killer cell receptor confers class I major histocompatibility complex (MHC)-specific inhibition and prevents bone marrow allograft rejection. [PDF]
, 1996 Natural killer (NK) cells and some T cells are endowed with receptors specific for class I major histocompatibility complex (MHC) molecules that can inhibit cellular effector functions.
Cado, D, Held, W, RAULET, David H.
core +1 more source
Frontiers in Immunology, 2015 There is compelling clinical and experimental evidence to suggest natural killer (NK) cells play a critical role in the recognition and eradication of tumors.
Cariad eChester +3 more
doaj +1 more source
Human innate immune cell crosstalk induces melanoma cell senescence
OncoImmunology, 2020 Mononuclear phagocytes and NK cells constitute the first line of innate immune defense. How these cells interact and join forces against cancer is incompletely understood.
Felix Funck +10 more
doaj +1 more source